Patents by Inventor Andre Leger

Andre Leger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4327095
    Abstract: Compounds of the formula: ##STR1## wherein A represents pyrid-2-yl, quinol-2-yl or 1,8-naphthyridin-2-yl, each such radical being optionally substituted by a halogen atom, or an alkyl or alkoxy radical of 1 through 4 carbon atoms, and R represents hydrogen, an alkyl radical of 1 through 4 carbon atoms, an alkenyl radical of 2 through 4 carbon atoms or an alkanoyl radical of 1 through 4 carbon atoms, are new compounds possessing pharmacological properties. They are particularly active as tranquillizers, anti-convulsants, decontracturants and hypnogenic agents.
    Type: Grant
    Filed: March 13, 1980
    Date of Patent: April 27, 1982
    Assignee: Rhone-Poulenc Industries
    Inventors: Daniel Farge, Andre Leger, Gerard Ponsinet
  • Patent number: 4271167
    Abstract: New dithiocarbamates of the formula: ##STR1## in which R.sub.1 is hydrogen or halogen in the 4-, 5- or 6-position, n is equal to 0 or 1, R.sub.2 represents hydrogen or various aliphatic or aromatic radicals which may be substituted, R.sub.3 represents hydrogen or various aliphatic radicals, and R.sub.4 represents a hydrogen atom or an alkyl radical, their optically active forms, and their salts, when such salts exist, are valuable anthelmintic agents. They may be made inter alia by reduction of the corresponding ketones.
    Type: Grant
    Filed: November 14, 1979
    Date of Patent: June 2, 1981
    Assignee: Rhone-Poulenc Industries
    Inventors: Jean-Dominique Bourzat, Daniel Farge, Andre Leger, Gerard Ponsinet
  • Patent number: 4271156
    Abstract: Compounds of the general formula: ##STR1## wherein R.sub.1 represents hydrogen or halogen in the 4-, 5- or 6-position of the pyridyl radical and R.sub.2 represents hydrogen, straight- or branched-chain alkyl of 1 to 4 carbon atoms or phenyl, possess anthelmintic activity, having a broad spectrum of activity against nematodes.
    Type: Grant
    Filed: November 14, 1979
    Date of Patent: June 2, 1981
    Assignee: Rhone-Poulenc Industries
    Inventors: Jean-Dominique Bourzat, Daniel Farge, Andre Leger, Gerard Ponsinet
  • Patent number: 4185107
    Abstract: 4-Methyl-3-(pyrid-2-yl)-.DELTA..sup.4 -thiazoline-2-thione, a known compound, has been found to be useful as an anti-ulcer medicament.
    Type: Grant
    Filed: October 17, 1978
    Date of Patent: January 22, 1980
    Assignee: Rhone-Poulenc Industries
    Inventors: Jean-Dominique Bourzat, Daniel Farge, Andre Leger, Gerard Ponsinet
  • Patent number: 4167571
    Abstract: New thiazoline derivaties of the formula: ##STR1## wherein R.sub.1 represents hydrogen, an alkyl radical of 1 or 2 carbon atoms or methoxymethyl, R.sub.2 represents an alkyl radical of 1 or 2 carbon atoms in the 4-, 5- or 6-position, and R.sub.3 represents methyl, or alternatively R.sub.3 represents hydrogen and either R.sub.1 represents hydrogen, an alkyl radical of 1 through 4 carbon atoms, or an alkoxymethyl radical in which the alkyl moiety contains 1 through 4 carbon atoms, and R.sub.2 represents an alkyl radical of 1 through 4 carbon atoms in the 4-, 5- or 6-position, or R.sub.1 represents cyclopropyl and R.sub.2 represents hydrogen are useful as medicaments and, more particularly, as anti-ulcer agents.
    Type: Grant
    Filed: October 17, 1978
    Date of Patent: September 11, 1979
    Assignee: Rhone-Poulenc Industries
    Inventors: Jean D. Bourzat, Daniel Farge, Andre Leger, Gerard Ponsinet
  • Patent number: 4164579
    Abstract: Compounds of the formula: ##STR1## wherein R.sub.1 represents alkyl of 1 through 4 carbon atoms in the 4-, 5- or 6-position of the pyridyl radical, and R.sub.2 represents hydrogen or alkyl of 1 through 4 carbon atoms, are useful as anti-ulcer agents.
    Type: Grant
    Filed: May 16, 1978
    Date of Patent: August 14, 1979
    Assignee: Rhone-Poulenc Industries
    Inventors: Jean D. Bourzat, Daniel Farge, Andre Leger, Gerard Ponsinet
  • Patent number: 4131674
    Abstract: Heterocyclic compounds of the formula: ##STR1## wherein the pyrroline ring and the symbols X.sub.1 and X.sub.2 together form an unsubstituted or substituted isoindoline nucleus, or a 6,7-dihydro-5H-pyrrolo[3,4-b]pyrazine, 6,7-dihydro-5H-pyrrolo[3,4-b]pyridine or 2,3,6,7-tetrahydro-5H-1,4-oxathiino[2,3-c]pyrrole nucleus, the 1,8-naphthyridin-2-yl nucleus is unsubstituted or substituted, and the grouping --NR.sub.1 R.sub.2 is an amino or substituted amino group, are new compounds which are active as tranquillizers, hypnotics, anti-convulsant agents and anti-spasmodics.
    Type: Grant
    Filed: October 19, 1977
    Date of Patent: December 26, 1978
    Assignee: Rhone-Poulenc Industries
    Inventors: Claude Cotrel, Cornel Crisan, Claude Jeanmart, Andre Leger
  • Patent number: 4124711
    Abstract: Compounds of the formula: ##STR1## wherein A represents a phenyl, pyrid-2-yl, quinol-2-yl or 1,8-naphthyridin-2-yl radical, each such radical being optionally substituted by a halogen atom, an alkyl radical of 1 through 4 carbon atoms, an alkoxy radical of 1 through 4 carbon atoms, the cyano or nitro radical, and R represents hydrogen or an alkyl radical of 1 through 4 carbon atoms, an alkenyl radical of 2 through 4 carbon atoms or an alkanoyl radical of 1 through 4 carbon atoms, possess pharmacological properties and are particularly active as tranquillizers, anti-convulsant agents, decontracturants and agents to produce hypnosis.
    Type: Grant
    Filed: February 17, 1977
    Date of Patent: November 7, 1978
    Assignee: Rhone-Poulenc Industries
    Inventors: Claude Jeanmart, Andre Leger
  • Patent number: 4086348
    Abstract: Heterocyclic compounds of the formula: ##STR1## wherein the pyrroline ring and the symbols X.sub.1 and X.sub.2 together form an unsubstituted or substituted isoindoline nucleus, or a 6,7-dihydro-5H-pyrrolo[3,4-b]pyrazine, 6,7-dihydro-5H-pyrrolo[3,4-b]pyridine or 2,3,6,7-tetrahydro-5H-1,4-oxathiino[2,3-c]pyrrole nucleus, the 1,8-naphthyridin-2-yl nucleus is unsubstituted or substituted, and the grouping --NR.sub.1 R.sub.2 is an amino or substituted amino group, are new compounds which are active as tranquillizers, hypnotics, anti-convulsant agents and anti-spasmodics.
    Type: Grant
    Filed: April 5, 1976
    Date of Patent: April 25, 1978
    Assignee: Rhone-Poulenc Industries
    Inventors: Claude Cotrel, Cornel Crisan, Claude Jeanmart, Andre Leger
  • Patent number: 3966931
    Abstract: New compounds of the formula: ##SPC1##Wherein A is a phenyl, pyridyl, pyridazinyl, 2-, 3- or 4-quinolyl or naphthyridinyl radical, or a said radical substituted by one or two atoms or radicals selected from halogen, alkyl, alkoxy cyano and nitro, R is alkyl, alkenyl or hydroxyalkyl, and n is zero or 1, possess pharmacological properties and are, in particular, active as tranquilizers, anti-convulsant agents, decontracturants and agents to produce hypnosis.
    Type: Grant
    Filed: June 24, 1975
    Date of Patent: June 29, 1976
    Assignee: Rhone-Poulenc S.A.
    Inventors: Claude Jeanmart, Andre Leger, Mayer Naoum Messer
  • Patent number: 3948917
    Abstract: New compounds of the formula: ##SPC1##Wherein A is a phenyl, pyridyl, pyridazinyl, 2-, 3- or 4-quinolyl or naphthyridinyl radical, or a said radical substituted by one or two atoms or radicals selected from halogen, alkyl, alkoxy cyano and nitro, R is alkyl, alkenyl or hydroxyalkyl, and n is zero or 1, possess pharmacological properties and are, in particular, active as tranquilisers, anti-convulsant agents, decontracturants and agents to produce hypnosis.
    Type: Grant
    Filed: December 3, 1973
    Date of Patent: April 6, 1976
    Assignee: Rhone-Poulenc S.A.
    Inventors: Claude Jeanmart, Andre Leger, Mayer Naoum Messer