Patents by Inventor Andre Malanda

Andre Malanda has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • N-(Heteroaryl)-1-heteroarylalky1-1H-indole-2-carboxamide derivatives, preparation and therapeutic use thereof
    Patent number: 8735432
    Abstract: The invention concerns compounds of general formula (I), wherein n, X1, X2, X3, X4, Y and W are as defined herein. The invention also concerns a method for preparing said compounds and their therapeutic use.
    Type: Grant
    Filed: October 23, 2012
    Date of Patent: May 27, 2014
    Assignee: Sanofi
    Inventors: Laurent Dubois, Yannick Evanno, Andre Malanda
  • -(amino-heteroaryl)-1-pyrrolopyridine-2-carboxamides derivatives preparation thereof and their use in therapy
    Patent number: 8716273
    Abstract: The invention relates to compounds of the general formula (I): Wherein X, Y, Z, Z1, Z2, Z3, Z4 and n are as defined herein. The invention also relates to a method for making the same and to the use thereof in therapy.
    Type: Grant
    Filed: February 10, 2012
    Date of Patent: May 6, 2014
    Assignee: SANOFI
    Inventors: Laurent Dubois, Yannick Evanno, Catherine Gille, David Machnik, Andre Malanda
  • -(amino-heteroaryI)-1-pyrrolopyridine-2-carboxamides derivatives preparation thereof and their use in therapy
    Patent number: 8716272
    Abstract: The invention relates to compounds of the general formula (I): Wherein X, Y, Z, Z1, Z2, Z3, Z4 and n are as defined herein. The invention also relates to a method for making the same and to the use thereof in therapy.
    Type: Grant
    Filed: February 10, 2012
    Date of Patent: May 6, 2014
    Assignee: Sanofi
    Inventors: Laurent Dubois, Yannick Evanno, Catherine Gille, David Machnik, Andre Malanda
  • Bicyclic derivatives of azabicyclic carboxamides, preparation thereof and therapeutic use thereof
    Patent number: 8604050
    Abstract: The disclosure relates to compounds of formula (I): wherein X1, X2, X3, X4, Y, n, A, and W are as defined in the disclosure, or a salt thereof, or a hydrate or solvate thereof, and to processes for the preparation of these compounds and the therapeutic use thereof.
    Type: Grant
    Filed: May 8, 2012
    Date of Patent: December 10, 2013
    Assignee: Sanofi
    Inventors: Laurent Dubois, Yannick Evanno, Catherine Gille, Andre Malanda
  • N-(Aminoheteroaryl)-1H-indole-2-carboxamide derivatives, and preparation and therapeutic application thereof
    Patent number: 8586573
    Abstract: The invention concerns compounds of general formula (I): Wherein n, X1, X2, X3, X4, Y, Z, Z1, Z2, Z3 and Z4 are as defined herein. The invention also concerns a process for the preparation of compounds of formula (I) and their therapeutic use.
    Type: Grant
    Filed: July 19, 2010
    Date of Patent: November 19, 2013
    Assignee: Sanofi
    Inventors: Laurent Dubois, Yannick Evanno, Andre Malanda, David Machnik, Catherine Gille
  • N-(aminoheteroaryl)-1H-indole-2-carboxamide derivatives, preparation thereof and therapeutic use therof
    Patent number: 8481745
    Abstract: The invention relates to compounds of general formula (I): Wherein n, X1, X2, X3, X4, Y, Z1, Z2, Z3, Z4, Ra and Rb are as defined herein. The invention also relates to process for the preparation of compounds of formula (I) and their therapeutic use.
    Type: Grant
    Filed: June 22, 2012
    Date of Patent: July 9, 2013
    Assignee: Sanofi
    Inventors: Laurent Dubois, Yannick Evanno, Andre Malanda
  • Tricyclic N-heteroaryl-carboxamide derivatives, preparation and therapeutic use thereof
    Patent number: 8420817
    Abstract: The invention relates to tricyclic N-heteroaryl-carboxamide derivatives having the formula (I): Wherein A, P, W, Z1, Z2, Z3, Z4, Z5, Z6, Z7, Z8, R3 and R3? are as described herein. The invention also relates to a method for preparing the same and to the therapeutic use thereof.
    Type: Grant
    Filed: March 6, 2012
    Date of Patent: April 16, 2013
    Assignee: Sanofi
    Inventors: Laurent Dubois, Yannick Evanno, Andre Malanda
  • N-(Heteroaryl)-1-heteroarylalkyl-1H-indole-2-carboxamide derivatives, preparation and therapeutic use thereof
    Publication number: 20130046095
    Abstract: The invention concerns compounds of general formula (I), wherein n, X1, X2, X3, X4, Y and W are as defined herein. The invention also concerns a method for preparing said compounds and their therapeutic use.
    Type: Application
    Filed: October 23, 2012
    Publication date: February 21, 2013
    Inventors: Laurent DUBOIS, Yannick EVANNO, Andre MALANDA
  • -(heteroaryl)-1-heteroarylalkyl-1-indole-2-carboxamide derivatives, preparation and therapeutic use thereof
    Patent number: 8318775
    Abstract: The invention concerns compounds of general formula (I), wherein n, X1, X2, X3, X4, Y and W are as defined herein. The invention also concerns a method for preparing said compounds and their therapeutic use.
    Type: Grant
    Filed: May 11, 2010
    Date of Patent: November 27, 2012
    Assignee: Sanofi
    Inventors: Laurent Dubois, Yannick Evanno, Andre Malanda
  • N-(AMINOHETEROARYL)-1H-INDOLE-2-CARBOXAMIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEROF
    Publication number: 20120264944
    Abstract: The invention relates to compounds of general formula (I): Wherein n, X1, X2, X3, X4, Y, Z1, Z2, Z3, Z4, Ra and Rb are as defined herein. The invention also relates to process for the preparation of compounds of formula (I) and their therapeutic use.
    Type: Application
    Filed: June 22, 2012
    Publication date: October 18, 2012
    Applicant: SANOFI
    Inventors: Laurent Dubois, Yannick Evanno, Andre Malanda
  • Tricyclic -heteroaryl-carboxamide derivatives containing a benzimidazole unit, method for preparing same and their therapeutic use
    Patent number: 8288376
    Abstract: The invention concerns tricyclic N-heteroaryl-carboxamide derivatives containing a benzimidazole unit of general formula (I): Wherein A, P, Y, R1, R2 and R3 are as defined herein. The invention also concerns a method of preparing the compounds and their therapeutic use.
    Type: Grant
    Filed: January 24, 2012
    Date of Patent: October 16, 2012
    Assignee: Sanofi
    Inventors: Laurent Dubois, Yannick Evanno, Luc Even, Catherine Gille, Andre Malanda, David Machnik, Nathalie Rakotoarisoa
  • N-(aminoheteroaryl)-1H-indole-2-carboxamide derivatives, preparation thereof and therapeutic use thereof
    Patent number: 8227489
    Abstract: The invention relates to compounds of general formula (I): Wherein n, X1, X2, X3, X4, Y, Z1, Z2, Z3, Z4, Ra and Rb are as defined herein. The invention also relates to process for the preparation of compounds of formula (I) and their therapeutic use.
    Type: Grant
    Filed: January 23, 2009
    Date of Patent: July 24, 2012
    Assignee: Sanofi-Aventis
    Inventors: Laurent Dubois, Yannick Evanno, Andre Malanda
  • Tricyclic N-heteroaryl-carboxamide derivatives, preparation and therapeutic use thereof
    Publication number: 20120165531
    Abstract: The invention relates to tricyclic N-heteroaryl-carboxamide derivatives having the formula (I): Wherein A, P, W, Z1, Z2, Z3, Z4, Z5, Z6, Z7, Z8, R3 and R3? are as described herein. The invention also relates to a method for preparing the same and to the therapeutic use thereof.
    Type: Application
    Filed: March 6, 2012
    Publication date: June 28, 2012
    Applicant: SANOFI-AVENTIS
    Inventors: Laurent DUBOIS, Yannick EVANNO, Andre MALANDA
  • TRICYCLIC N-HETEROARYL-CARBOXAMIDE DERIVATIVES CONTAINING A BENZIMIDAZOLE UNIT, METHOD FOR PREPARING SAME AND THEIR THERAPEUTIC USE
    Publication number: 20120122852
    Abstract: The invention concerns tricyclic N-heteroaryl-carboxamide derivatives containing a benzimidazole unit of general formula (I): Wherein A, P, Y, R1, R2 and R3 are as defined herein. The invention also concerns a method of preparing the compounds and their therapeutic use.
    Type: Application
    Filed: January 24, 2012
    Publication date: May 17, 2012
    Applicant: SANOFI-AVENTIS
    Inventors: Laurent DUBOIS, Yannick EVANNO, Luc EVEN, Catherine GILLE, Andre MALANDA, David MACHNIK, Nathalie RAKOTOARISOA
  • Tricyclic -heteroaryl-carboxamide derivatives, preparation and therapeutic use thereof
    Patent number: 8153796
    Abstract: The invention relates to tricyclic N-heteroaryl-carboxamide derivatives having the formula (I): Wherein A, P, W, Z1, Z2, Z3, Z4, Z5, Z6, Z7, Z8, R3 and R3? are as described herein. The invention also relates to a method for preparing the same and to the therapeutic use thereof.
    Type: Grant
    Filed: January 29, 2010
    Date of Patent: April 10, 2012
    Assignee: Sanofi-Aventis
    Inventors: Laurent Dubois, Yannick Evanno, Andre Malanda
  • Tricyclic N-heteroaryl-carboxamide derivatives containing a benzimidazole unit, method for preparing same and their therapeutic use
    Patent number: 8143248
    Abstract: The invention concerns tricyclic N-heteroarylcarboxamide derivatives containing a benzimidazole unit of general formula (I): Wherein A, P, Y, R1, R2 and R3 are as defined herein. The invention also concerns a method of preparing the compounds and their therapeutic use.
    Type: Grant
    Filed: August 1, 2008
    Date of Patent: March 27, 2012
    Assignee: Sanofi-Aventis
    Inventors: Laurent Dubois, Yannick Evanno, Luc Even, Catherine Gille, Andre Malanda, David Machnik, Nathalie Rakotoarisoa
  • POLYSUBSTITUTED 2-ARYL-6-PHENYLIMIDAZO[1,2-A]PYRIDINE DERIVATIVES, AND PREPARATION AND THERAPEUTIC USE THEREOF
    Publication number: 20110065745
    Abstract: Compounds of formula (I): wherein R, R1, R2, R3, R4, and X are as defined in the disclosure, or an acid addition salt thereof, and the therapeutic use and process of synthesis thereof.
    Type: Application
    Filed: September 14, 2010
    Publication date: March 17, 2011
    Applicant: SANOFI-AVENTIS
    Inventors: Danielle DE PERETTI, Yannick EVANNO, Patrick LARDENOIS, Nathalie RAKOTOARISOA, Antonio ALMARIO GARCIA, Andre MALANDA
  • N-(Aminoheteroaryl)-1H-indole-2-carboxamide derivatives, and preparation and therapeutic application thereof
    Publication number: 20100286119
    Abstract: The invention concerns compounds of general formula (I): Wherein n, X1, X2, X3, X4, Y, Z, Z1, Z2, Z3 and Z4 are as defined herein. The invention also concerns a process for the preparation of compounds of formula (I) and their therapeutic use.
    Type: Application
    Filed: July 19, 2010
    Publication date: November 11, 2010
    Applicant: SANOFI-AVENTIS
    Inventors: Laurent DUBOIS, Yannick EVANNO, Andre MALANDA, David MACHNIK, Catherine GILLE
  • THERAPEUTIC USE OF N-(ARYLALKYL)-1H-PYRROLOPYRIDINE-2-CARBOXAMIDE DERIVATIVES
    Publication number: 20100249183
    Abstract: The invention concerns therapeutic use of compounds of general formula (I), wherein n, the pyrrolopyridine ring, X1, Z1, Z2, Z3, Z4, Z5 and W are as defined herein.
    Type: Application
    Filed: June 15, 2010
    Publication date: September 30, 2010
    Applicant: SANOFI-AVENTIS
    Inventors: Laurent DUBOIS, Yannick EVANNO, Andre MALANDA
  • N-(Heteroaryl)-1-heteroarylalkyl-1H-indole-2-carboxamide derivatives, preparation and therapeutic use thereof
    Publication number: 20100222368
    Abstract: The invention concerns compounds of general formula (I), wherein n, X1, X2, X3, X4, Y and W are as defined herein. The invention also concerns a method for preparing said compounds and their therapeutic use.
    Type: Application
    Filed: May 11, 2010
    Publication date: September 2, 2010
    Applicant: SANOFI-AVENTIS
    Inventors: Laurent DUBOIS, Yannick EVANNO, Andre MALANDA