Patents by Inventor Andre PALMER

Andre PALMER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240168005
    Abstract: The present disclosure provides methods to diagnose and/or treat hemoglobinopathies via comparative analysis of cell magnetic properties.
    Type: Application
    Filed: March 7, 2022
    Publication date: May 23, 2024
    Inventors: Jeffrey CHALMERS, Andre PALMER, Payal DESAI
  • Patent number: 11938327
    Abstract: A stimulation system for a patient is provided. The system comprises: at least one implantable device comprising at least one implantable antenna; and an external device comprising at least one external antenna, wherein the at least one external antenna transfers power to the at least one implantable antenna. The at least one implantable device delivers therapy to the patient. A patient attachment device or body covering positions the at least one external antenna relative to the patient.
    Type: Grant
    Filed: September 29, 2021
    Date of Patent: March 26, 2024
    Assignee: Nalu Medical, Inc.
    Inventors: Lee Fason Hartley, Christopher Linden, Daniel M. Pivonka, Ji-Jon Sit, Lakshmi Narayan Mishra, Logan Palmer, Brett Daniel Schleicher, Mark David Londborg, James Goodman, James C. Makous, Andre Castillo
  • Publication number: 20230330192
    Abstract: Disclosed are method of using compositions comprising PolyHSA to preventing, protecting and/or treating conditions such as endothelial dysfunction, and hypercytokinemia.
    Type: Application
    Filed: September 6, 2021
    Publication date: October 19, 2023
    Inventors: Andre PALMER, Pedro J. CABRALES AREVALO
  • Publication number: 20230303622
    Abstract: Tangential flow filtration (TFF) is a size-based separation method conventionally used for buffer exchange, concentration, pathogen removal, and for coarse purification. Disclosed herein, TFF was used for selective purification of proteins in their complexed form. In some examples, this process was demonstrated to recover human serum albumin (HSA) in its complexed form from an artificially produced mixture of hemoglobin (Hb) and HSA and from plasma using an anti-HSA polyclonal immunoglobulin G (IgG) as the target-protein binding molecule (TPBM). Moreover, another embodiment of the method recovered haptoglobin (Hp) in its complexed form from human Cohn Fraction IV using Hb as the TPBM. In addition, a mathematical model used to describe the TFF purification process provided that product recovery could be increased without loss of purity by introducing TFF filters with the same MWCO in series.
    Type: Application
    Filed: August 30, 2021
    Publication date: September 28, 2023
    Inventors: Ivan SUSIN PIRES, Andre PALMER
  • Publication number: 20230181688
    Abstract: The present disclosure provides methods of treating plasma protein imbalances or depletion (e.g., plasma protein imbalances or depletion caused by hemorrhagic shock or other clinical conditions), in particular by administering protein compositions derived from plasma or plasma isolates.
    Type: Application
    Filed: March 22, 2021
    Publication date: June 15, 2023
    Inventors: Ivan SUSIN PIRES, Andre PALMER, Pedro J. CABRALES AREVALO
  • Publication number: 20230003734
    Abstract: Methods for purifying and isolating extracellular vesicles (EVs) from a biofluid using a sequential processing. Tangential flow filtration is applied to the biofluid to increase the concentration of EVs in the biofluid. After this is achieved, enrichment mode is halted and the biofluid is processed in diafiltration mode to remove contaminants (up to 99.9%). After performing the tangential flow filtration step, the concentration of EVs in the biofluid is further increased by ultracentrifugal filtration. After performing the ultracentrifugal filtration step, EVs of a particular target type are separated from other EVs by immunomagnetic affinity separation. In some implementations, the methods are used to isolate and quantify tumor EVs for cancer evaluation. Additionally, these methods can be used with a scaling factor to quantify EVs from a less concentrated biofluid such as, for example, urine.
    Type: Application
    Filed: December 8, 2020
    Publication date: January 5, 2023
    Inventors: Eduardo Reategui, Andre Palmer, Jingjing Zhang, Richard Hickey, Thi Hien Luong Nguyen
  • Publication number: 20220313792
    Abstract: Disclosed herein are oxygen transporting formulations, in particular those composed of hemoglobin-based nanoparticles, and their use and process of manufacture. These formulations are more uniform and monodisperse than prior hemoglobin-based oxygen carriers, such as polymeric hemoglobin. In addition, these formulations provide higher hemoglobin encapsulation efficiencies and higher hemoglobin content that hemoglobin-containing vesicles.
    Type: Application
    Filed: August 28, 2020
    Publication date: October 6, 2022
    Inventors: Richard HICKEY, Andre PALMER
  • Publication number: 20220218834
    Abstract: Provided herein are apohemoglobin-haptoglobin complexes as well as apohemoglobin-haptoglobin complexes comprising an active agent coordinated thereto. Methods of using these compositions are also described.
    Type: Application
    Filed: May 20, 2020
    Publication date: July 14, 2022
    Inventors: Ivan SUSIN PIRES, Andre PALMER, Pedro J. CABRALES AREVALO
  • Publication number: 20220098234
    Abstract: Provided herein are methods for purifying proteins from mixtures of proteins using ultrafiltration, such as tangential-flow filtration (TFF). Provided herein are methods for isolating an apoprotein from a protein solution comprising a conjugated protein, wherein the conjugated protein comprises the apoprotein and a hydrophobic ligand associated with the apoprotein.
    Type: Application
    Filed: January 31, 2020
    Publication date: March 31, 2022
    Inventors: Ivan SUSIN PIRES, Andre PALMER, Donald BELCHER