Patents by Inventor Andre Poittevin

Andre Poittevin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4108994
    Abstract: A 5-thiazole-methane-amine selected from the group consisting of (1) compounds having the formula ##STR1## wherein R.sub.1 represents an alkyl having from 1 to 6 carbon atoms and R.sub.2 and R.sub.3 represent members selected from the group consisting of hydrogen, alkyl having from 1 to 6 carbon atoms, hydroxyalkyl having 1 to 6 carbon atoms, and, taken together, alkylene having up to 5 carbon atoms, azaalkylene having up to 4 carbon atoms, alkylalkylene having up to 5 carbon atoms in the alkylene and 1 to 4 carbon atoms in the alkyl, and alkylazaalkylene having up to 4 carbon atoms in the azaalkylene and 1 to 4 carbon atoms in the alkyl which may be in any position, and (2) its acid addition salts with non-toxic, pharmaceutically-acceptible acids; as well as processes for the preparation of the compounds and a process for use of the compounds as an antilipolytic agent.
    Type: Grant
    Filed: September 8, 1976
    Date of Patent: August 22, 1978
    Assignee: Roussel Uclaf
    Inventors: Andre Poittevin, Pierre Henri Derible, Robert Fournex
  • Patent number: 4073919
    Abstract: Novel 5-thiazole alkanols of the formula ##STR1## wherein R is alkyl of 1 to 5 carbon atoms, n is an integer from 2 to 7 and R.sub.1 is selected from the group consisting of hydrogen and acyl of an alkanoic acid of 2 to 6 carbon atoms and their non-toxic, pharmaceutically acceptable acid addition salts having a marked antilipolytic activity and useful as intermediates and their preparation.
    Type: Grant
    Filed: February 2, 1976
    Date of Patent: February 14, 1978
    Assignee: Roussel Uclaf
    Inventors: Andre Poittevin, Vesperto Torelli
  • Patent number: 4053618
    Abstract: Novel thiazole derivatives of the formula ##STR1## wherein R is alkyl of 1 to 5 carbon atoms, Z is selected from the group consisting of --CH.dbd.CH--, --CH.dbd.CH--CH.dbd.CH-- and (CH.sub.2).sub.n --, n is an integer from 1 to 6 and R.sub.1 is selected from the group consisting of hydrogen, alkyl of 1 to 5 carbon atoms, --NH.sub.4 and alkali metal, alkaline earth metal and aluminum cations and the non-toxic, pharmaceutically acceptable acid addition salts thereof which have antilipolytic activity and are useful intermediates and their preparation and intermediates produced therein.
    Type: Grant
    Filed: February 2, 1976
    Date of Patent: October 11, 1977
    Assignee: Roussel-UCLAF
    Inventors: Andre Poittevin, Vesperto Torelli
  • Patent number: 4032643
    Abstract: Novel substituted thiazoles of the formula ##STR1## wherein R is alkyl of 1 to 5 carbon atoms and R.sub.1 is selected from the group consisting of --NH.sub.2, -- NH-AlK, ##STR2## PHENYLAMINO AND DIPHENYLAMINO, AlK is alkyl of 1 to 4 carbon atoms and n is an integer from 1 to 6 and their non-toxic, pharmaceutically acceptable acid addition salts having a marked antilipolytic activity and for some of them, a prolonged vasodilatatory activity and an antibradykinetic activity and their preparation.
    Type: Grant
    Filed: February 2, 1976
    Date of Patent: June 28, 1977
    Assignee: Roussel-UCLAF
    Inventors: Andre Poittevin, Vesperto Torelli
  • Patent number: 4001447
    Abstract: Novel 2-hydroxymethyl-thiazole-5-carboxylic acid derivatives of the formula ##STR1## wherein R is selected from the group consisting of hydrogen, alkyl of 1 to 4 carbon atoms, alkylcarbonyl of 2 to 5 carbon atoms, benzoyl, phenyl optionally substituted with at least one halogen and ##STR2## R.sub.1 and R.sub.2 are individually selected from the group consisting of hydrogen and alkyl of 1 to 3 carbon atoms, Z is selected from the group of phenyl and phenoxy optionally substituted with at least one halogen and R' is selected from the group consisting of hydrogen and alkyl of 1 to 4 carbon atoms and alkali metals, alkaline earth metals and aluminum salts, having a marked hypolipemiant activity as well as a clear vasodilatatory activity and which may possess hypocholesterolemiant activity and their preparation.
    Type: Grant
    Filed: October 15, 1975
    Date of Patent: January 4, 1977
    Assignee: Roussel-UCLAF
    Inventors: Andre Poittevin, Michel Hardy
  • Patent number: 3983129
    Abstract: Novel 3-phosphoryloxy-isothiazoles of the formula ##SPC1##Wherein R is selected from the group consisting of alkyl of 1 to 3 carbon atoms, alkoxy of 1 to 3 carbon atoms and ##EQU1## R' and R" being individually SELECTED FROM THE GROUP CONSISTING OF HYDROGEN AND ALKYL OF 1 TO 3 CARBON ATOMS, R.sub.1 is alkyl of 1 to 3 carbon atoms, R.sub.2 is selected from the group consisting of hydrogen, alkyl of 1 to 5 carbon atoms, aryl of 6 to 10 carbon atoms, aralkyl of 7 to 12 carbon atoms, cyano, carbalkoxy of 2 to 4 carbon atoms and NHR'", and R'" is selected from the group consisting of hydrogen and aryl of 6 to 10 carbon atoms, R.sub.
    Type: Grant
    Filed: January 13, 1975
    Date of Patent: September 28, 1976
    Assignee: Roussel-UCLAF
    Inventors: Jacques Perronnet, Laurent Taliani, Pierre Girault, Andre Poittevin
  • Patent number: 3979515
    Abstract: Novel 5-methyl-10-(.beta.-alkylaminoethyl)dibenzo(b,f) azepines of the formula ##SPC1##Wherein R is lower alkyl, R.sub.1 is selected from the group consisting of hydrogen and lower alkyl and X and X' are selected from the group consisting of hydrogen and halogen and their non-toxic, pharmaceutically acceptable acid addition salts having a superior thymoanaleptic activity and their preparation and use.
    Type: Grant
    Filed: December 18, 1974
    Date of Patent: September 7, 1976
    Assignee: Roussel-UCLAF
    Inventors: Andre Allais, Andre Poittevin
  • Patent number: 3957757
    Abstract: Novel 5-methyl-10-(.beta.-alkylaminoethyl)dibenzo(b,f) azepines of the formula ##SPC1##Wherein R is lower alkyl, R.sub.1 is selected from the group consisting of hydrogen and lower alkyl and X and X' are selected from the group consisting of hydrogen and halogen and their non-toxic, pharmaceutically acceptable acid addition salts having a superior thymoanaleptic activity and their preparation and use.
    Type: Grant
    Filed: November 15, 1974
    Date of Patent: May 18, 1976
    Assignee: Roussel-UCLAF
    Inventors: Andre Allais, Andre Poittevin