Abstract: Systems and associated methods for controlling roll steering during rolling of a metal substrate may include a steering control actuator adapted to control an inclination of a work roll of a work stand of the rolling mill, a sensor configured to measure a parameter of a metal substrate upstream from the work stand, and a controller operably connected with the steering control actuator and the sensor. The controller may generate a model for the work stand and determine an adjustment value for the work stand, receive the measured parameter from the sensor, and determine an expected output parameter by adjusting the measured parameter by the adjustment value. The controller may also compare the expected output parameter with a target output parameter and actuate the steering control actuator such that the expected output parameter is within a predefined tolerance of the target parameter.

Abstract: A centrifuge tube fermenter for culturing cells in a nutrient medium wherein the centrifuge tube fermenter is comprised of a top end, a bottom end, a vertical cylindrical outer wall positioned between the top end and the bottom end, and an inner wall positioned inside the outer wall, the bottom end further comprised of a plurality of baffles which protrude from inner wall toward a theoretical center of the vertical cylindrical outer wall terminating in a conical tip.