Abstract: The present disclosure relates to a system and method for use in performing clinical endpoint adjudication to provide: efficient, automated clinical event classification and medical review triage; reduce the time to identify clinical events; a unified, consistent process for classification of clinical events; and proactive identification of events in near real-time.

Abstract: A cartridge retainer comprises a sleeve having a distal end a proximal end and a longitudinal axis extending between the distal end and the proximal end. One or more tabs extend radially from the sleeve toward the longitudinal axis and are configured to radially deflect away from the longitudinal axis. One or more deformable members extend axially from the distal end of the sleeve toward the one or more tabs and are configured to deform in a longitudinal direction toward the distal end.

Abstract: A cartridge retainer comprises a sleeve having a distal end a proximal end and a longitudinal axis extending between the distal end and the proximal end. One or more tabs extend radially from the sleeve toward the longitudinal axis and are configured to radially deflect away from the longitudinal axis. One or more deformable members extend axially from the distal end of the sleeve toward the one or more tabs and are configured to deform in a longitudinal direction toward the distal end.

Abstract: A cartridge retainer comprises a sleeve having a distal end a proximal end and a longitudinal axis extending between the distal end and the proximal end. One or more tabs extend radially from the sleeve toward the longitudinal axis and are configured to radially deflect away from the longitudinal axis. One or more deformable members extend axially from the distal end of the sleeve toward the one or more tabs and are configured to deform in a longitudinal direction toward the distal end.

Abstract: A solid product dispenser can be used to form a dilute liquid solution from a block of solid concentrate. In cases where only a small amount of liquid solution is needed, the solid product dispenser may dissolve the block of solid concentrate quickly and substantially uniformly to provide a solution of controlled concentration. This can be contrast with larger dispensing applications where a dispenser may dissolve a block of concentrate slowly at the start and more rapidly as the dispensing progresses, producing a solution with an average concentration higher than if only a small amount of solution were produced using the dispenser. In one example, the solid product dispenser includes a fluid distribution reservoir and a solid product reservoir positioned inside of the fluid distribution reservoir and over a platform on which the solid product sits. High pressure fluid flows between the two reservoirs, turbulently contacting the solid product.

Abstract: A cartridge retainer comprises a sleeve having a distal end a proximal end and a longitudinal axis extending between the distal end and the proximal end. One or more tabs extend radially from the sleeve toward the longitudinal axis and are configured to radially deflect away from the longitudinal axis. One or more deformable members extend axially from the distal end of the sleeve toward the one or more tabs and are configured to deform in a longitudinal direction toward the distal end.

Abstract: A solid product dispenser can be used to form a dilute liquid solution from a block of solid concentrate. In cases where only a small amount of liquid solution is needed, the solid product dispenser may dissolve the block of solid concentrate quickly and substantially uniformly to provide a solution of controlled concentration. This can be contrast with larger dispensing applications where a dispenser may dissolve a block of concentrate slowly at the start and more rapidly as the dispensing progresses, producing a solution with an average concentration higher than if only a small amount of solution were produced using the dispenser. In one example, the solid product dispenser includes a fluid distribution reservoir and a solid product reservoir positioned inside of the fluid distribution reservoir and over a platform on which the solid product sits. High pressure fluid flows between the two reservoirs, turbulently contacting the solid product.

Abstract: An embodiment of a handle assembly for an elongate medical device that may reduce the weight and/or expense of traditional handle may include an exterior adjusting knob extending along a longitudinal axis and configured to rotate about the axis, an insert, and a dowel pin. The insert may be configured to engage the adjusting knob and to rotate about the axis responsive to rotation of the adjusting knob. The insert may comprise an annular groove configured to engage a dowel pin, the annular groove comprising a sidewall comprising a chamfer. The dowel pin may be configured to engage the annular groove to resist rotation of the insert. In an embodiment, the insert may comprise plastic or polymer.

Abstract: Database information may be accessed through a user interface comprising one or more interactive treemaps. Each interactive treemap reflects a hierarchical structure of the stored information, for example parent and child nodes. By providing one type of input (e.g., a reverse finger pinch) to a sub-area of the treemap, the user may cause a different treemap to be displayed reflecting the hierarchical structure (grandchild nodes) of the sub-area. A treemap may also be manipulated by a user to provide additional detail. For example, by providing another type of input (e.g., a finger tap) to a treemap sub-area, a user may cause further information relevant to a child node to be displayed as a pop-up or as a separate detail screen. The treemap views of the interface provide a user with fluid and intuitive navigation upward/downward through the hierarchy, with detail screens allowing access to additional stored database information as desired.

Abstract: An embodiment of a handle assembly for an elongate medical device that may reduce the weight and/or expense of traditional handle may include an exterior adjusting knob extending along a longitudinal axis and configured to rotate about the axis, an insert, and a dowel pin. The insert may be configured to engage the adjusting knob and to rotate about the axis responsive to rotation of the adjusting knob. The insert may comprise an annular groove configured to engage a dowel pin, the annular groove comprising a sidewall comprising a chamfer. The dowel pin may be configured to engage the annular groove to resist rotation of the insert. In an embodiment, the insert may comprise plastic or polymer.

Abstract: Target substrates are electrostatically coated by flowing an electrically isolated wet coating composition containing waterborne coalescable polymeric binder into an electrostatic coating apparatus (100), depositing the coating composition onto a rotating electrostatically-charged atomizer (104) and thence onto the target substrate, flowing an electrically isolated aqueous cleaning liquid into the apparatus before deposition of the coating composition onto the rotating atomizer is halted or interrupted, and depositing the aqueous cleaning liquid onto the atomizer before or within a sufficiently short time after a halt or interruption in coating composition deposition onto the atomizer so that a coalesced polymeric binder film does not accumulate on the atomizer.

Abstract: Articles containing thermoplastic, thermoplastic composite or thermoplastic-clad materials are made less susceptible to heat distortion by coating the article with a two-part aqueous coating composition whose first part contains a waterborne active hydrogen-functional latex binder and whose second part contains a water-dispersible polyisocyanate. One or both of the first and second parts contain non-infrared-absorptive colored pigment. A mixture of the first and second parts coated atop a vinyl substrate cures to form a vinyl-adherent, infrared-reflective colored protective film.