Patents by Inventor Andrea Azcarate-Peril

Andrea Azcarate-Peril has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR PRODUCING HUMAN MILK OLIGOSACCHARIDES
    Publication number: 20230279368
    Abstract: The present disclosure provides compositions and methods related to the production of human milk oligosaccharides (HMOs). In particular, the present disclosure provides compositions and methods for converting lactose and N-acetylglucosamine (GlcNAc) into N-acetyllactosamine (LacNAc)-enriched galactooligosaccharide (GOS) compositions using novel ?-hexosyl-transferase (BHT) enzymes.
    Type: Application
    Filed: May 18, 2021
    Publication date: September 7, 2023
    Inventors: Jose M. Bruno-Barcena, Suzanne Dagher, Maria Andrea Azcarate-Peril
  • nucleic acids and uses thereof
    Patent number: 7981651
    Abstract: Lactobacillus acidophilus NCFM nucleic acid molecules, polypeptides, fragments and variants thereof are provided in the current invention. In addition, fusion proteins, antigenic peptides, and antibodies are encompassed. The invention also provides recombinant expression vectors containing a nucleic acid molecule of the invention and cells comprising the expression vectors. Methods for producing the polypeptides of the invention and methods for their use are further provided.
    Type: Grant
    Filed: October 17, 2008
    Date of Patent: July 19, 2011
    Assignee: North Carolina State University
    Inventors: Todd R. Klaenhammer, Eric Altermann, Andrea Azcarate-Peril
  • NUCLEIC ACIDS ENCODING TWO-COMPONENT SENSING AND REGULATORY PROTEINS, ANTIMICROBIAL PROTEINS AND USES THEREFOR
    Publication number: 20100279349
    Abstract: Stress-related nucleic acid molecules and polypeptides and fragments and variants thereof are disclosed in the current invention. In addition, stress-related fusion proteins, antigenic peptides, and anti-stress-related antibodies are encompassed. The invention also provides recombinant expression vectors containing a nucleic acid molecule of the invention and cells into which the expression vectors have been introduced. Methods for producing the polypeptides and methods of use for the polypeptides of the invention are further disclosed.
    Type: Application
    Filed: April 30, 2010
    Publication date: November 4, 2010
    Applicant: NORTH CAROLINA STATE UNIVERSITY
    Inventors: TODD R. KLAENHAMMER, WILLIAM M. RUSSELL, ERIC ALTERMANN, ANDREA AZCARATE-PERIL
  • Nucleic acid encoding two-component sensing and regulatory proteins, antimicrobial proteins and uses therefor
    Patent number: 7754868
    Abstract: Stress-related nucleic acid molecules and polypeptides and fragments and variants thereof are disclosed in the current invention. In addition, stress-related fusion proteins, antigenic peptides, and anti-stress-related antibodies are encompassed. The invention also provides recombinant expression vectors containing a nucleic acid molecule of the invention and cells into which the expression vectors have been introduced. Methods for producing the polypeptides and methods of use for the polypeptides of the invention are further disclosed.
    Type: Grant
    Filed: March 11, 2008
    Date of Patent: July 13, 2010
    Assignee: North Carolina State University
    Inventors: Todd R. Klaenhammer, William M. Russell, Eric Altermann, Andrea Azcarate-Peril
  • LACTOBACILLUS ACIDOPHILUS NUCLEIC ACID SEQUENCES ENCODING STRESS-RELATED PROTEINS AND USES THEREFOR
    Publication number: 20100028945
    Abstract: Stress-related nucleic acid molecules and polypeptides and fragments and variants thereof are disclosed in the current invention. In addition, stress-related fusion proteins, antigenic peptides, and anti-stress-related antibodies are encompassed. The invention also provides recombinant expression vectors containing a nucleic acid molecule of the invention and host cells into which the expression vectors have been introduced. Methods for producing the polypeptides and methods of use for the polypeptides of the invention are further disclosed.
    Type: Application
    Filed: August 19, 2009
    Publication date: February 4, 2010
    Applicant: North Carolina State University
    Inventors: Todd R. Klaenhammer, Eric Altermann, M. Andrea Azcarate-Peril, Olivia McAuliffe, W. Michael Russell
  • nucleic acid sequences encoding stress-related proteins and uses therefor
    Patent number: 7608700
    Abstract: Stress-related nucleic acid molecules and polypeptides and fragments and variants thereof are disclosed in the current invention. In addition, stress-related fusion proteins, antigenic peptides, and anti-stress-related antibodies are encompassed. The invention also provides recombinant expression vectors containing a nucleic acid molecule of the invention and host cells into which the expression vectors have been introduced. Methods for producing the polypeptides and methods of use for the polypeptides of the invention are further disclosed.
    Type: Grant
    Filed: March 7, 2005
    Date of Patent: October 27, 2009
    Assignee: North Carolina State University
    Inventors: Todd R. Klaenhammer, Eric Altermann, M. Andrea Azcarate-Peril, Olivia McAuliffe, W. Michael Russell
  • Nucleic acid sequences encoding two-component sensing and regulatory proteins, antimicrobial proteins and uses therefor
    Patent number: 7550576
    Abstract: Stress-related nucleic acid molecules and polypeptides and fragments and variants thereof are disclosed in the current invention. In addition, stress-related fusion proteins, antigenic peptides, and anti-stress-related antibodies are encompassed. The invention also provides recombinant expression vectors containing a nucleic acid molecule of the invention and cells into which the expression vectors have been introduced. Methods for producing the polypeptides and methods of use for the polypeptides of the invention are further disclosed.
    Type: Grant
    Filed: August 8, 2005
    Date of Patent: June 23, 2009
    Assignee: North Carolina State University
    Inventors: Todd R. Klaenhammer, William M. Russell, Eric Altermann, Andrea Azcarate-Peril
  • COMPOSITIONS COMPRISING PROMOTER SEQUENCES AND METHODS OF USE
    Publication number: 20090155913
    Abstract: Nucleic acid molecules, fragments and variants thereof having promoter activity are provided in the current invention. The invention also provides vectors containing a nucleic acid molecule of the invention and cells comprising the vectors. Methods for making and using the nucleic acid molecules of the invention are further provided.
    Type: Application
    Filed: October 29, 2008
    Publication date: June 18, 2009
    Applicant: North Carolina State University
    Inventors: Rodolphe Barrangou, Andrea Azcarate-Peril, Eric Altermann, Tri Duong, Todd R. Klaenhammer
  • LACTOBACILLUS ACIDOPHILUS NUCLEIC ACIDS AND USES THEREOF
    Publication number: 20090155213
    Abstract: Lactobacillus acidophilus NCFM nucleic acid molecules, polypeptides, fragments and variants thereof are provided in the current invention. In addition, fusion proteins, antigenic peptides, and antibodies are encompassed. The invention also provides recombinant expression vectors containing a nucleic acid molecule of the invention and cells comprising the expression vectors. Methods for producing the polypeptides of the invention and methods for their use are further provided.
    Type: Application
    Filed: October 17, 2008
    Publication date: June 18, 2009
    Applicant: North Carolina State University
    Inventors: Andrea Azcarate-Peril, Eric Altermann, Todd Klaenhammer
  • Compositions comprising promoter sequences and methods of use
    Patent number: 7495092
    Abstract: Nucleic acid molecules, fragments and variants thereof having promoter activity are provided in the current invention. The invention also provides vectors containing a nucleic acid molecule of the invention and cells comprising the vectors. Methods for making and using the nucleic acid molecules of the invention are further provided.
    Type: Grant
    Filed: January 12, 2006
    Date of Patent: February 24, 2009
    Assignee: North Carolina State University
    Inventors: Rodolphe Barrangou, Andrea Azcarate-Peril, Eric Altermann, Tri Duong, Todd R. Klaenhammer
  • nucleic acids and uses thereof
    Patent number: 7468182
    Abstract: Lactobacillus acidophilus NCFM nucleic acid molecules, polypeptides, fragments and variants thereof are provided in the current invention. In addition, fusion proteins, antigenic peptides, and antibodies are encompassed. The invention also provides recombinant expression vectors containing a nucleic acid molecule of the invention and cells comprising the expression vectors. Methods for producing the polypeptides of the invention and methods for their use are further provided.
    Type: Grant
    Filed: October 27, 2005
    Date of Patent: December 23, 2008
    Assignee: North Carolina State University
    Inventors: Todd Klaenhammer, Andrea Azcarate-Peril, Eric Altermann
  • Methods and compositions to modulate adhesion and stress tolerance in bacteria
    Publication number: 20060269998
    Abstract: Methods and compositions are provided which improve the adhesion of a bacteria to target substrates and/or improve the stress tolerance of a bacteria. Methods comprise exposing bacteria to adhesion adaptive conditions and thereby increasing the adhesion activity and/or stress tolerance of the bacteria. Further provided are bacteria having a modulated production of autoinducer-2. Compositions include recombinant bacteria expressing nucleic acid molecules involved in the pathway of autoinducer-2 production. Further provided are autoinducer-2-related fusion proteins, antigenic peptides, antibodies, and vectors. Methods of screening compounds or environmental conditions which will stimulate the production of autoinducer-2 and/or produce an adhesion adaptive response are further provided, as are various methods of use for the bacteria having increased adhesion and/or stress tolerance.
    Type: Application
    Filed: April 14, 2006
    Publication date: November 30, 2006
    Applicant: North Carolina State University
    Inventors: B. Logan Buck, M. Andrea Azcarate-Peril, Eric Altermann, Todd Klaenhammer
  • Compositions comprising promoter sequences and methods of use
    Publication number: 20060166323
    Abstract: Nucleic acid molecules, fragments and variants thereof having promoter activity are provided in the current invention. The invention also provides vectors containing a nucleic acid molecule of the invention and cells comprising the vectors. Methods for making and using the nucleic acid molecules of the invention are further provided.
    Type: Application
    Filed: January 12, 2006
    Publication date: July 27, 2006
    Applicant: North Carolina State University
    Inventors: Rodolphe Barrangou, Andrea Azcarate-Peril, Eric Altermann, Tri Duong, Todd Klaenhammer