Abstract: In an apparatus and a packaging process of capsules with an opening closed by a laminar lid obtained by cutting a strip, the ability of transporting the laminar lids in several lines is introduced, reducing the overall dimensions. The apparatus includes: a cutting device with a mechanism defining a portion of the strip where the strip is tensioned in a respective cutting plane, and one or more punches obtaining the laminar lids from the strip; a carousel-like transfer device, having transfer members movable along a closed path, with gripping heads configured to receive respective laminar lids from the cutting device. The cutting plane is in a vertical position, and the mutual position of the cutting device and the transfer device defines a gripping spot of the closed path, the laminar lids being retained in the transfer members on a respective plane in a vertical position.

Abstract: A coupling unit for coupling a component for a container includes a coupling equipment. The coupling equipment includes: a frame, a housing constrained to the frame, a gripping device rotatably constrained with respect to the frame and including a retaining element to selectively retain the component, and a coupling device constrained to the gripping device with respect to the frame, the coupling device including a coupling element to constrain a portion of the component to a coupling surface of the container at a coupling position. The gripping device and the coupling device can move along an arc with a curved trajectory to a removal position where the retaining element is oriented to receive at least one component to be retained, and to a coupling position where the retaining element and the coupling element bring an abutment surface of the container and a couplable portion of the component into contact.

Abstract: A cap assembly is disclosed that creates a gas-tight seal with a cell can housing. The cap assembly has an outer surface, an inner surface and a perimeter edge. The cap assembly further includes an electrolyte injection port forming a port opening between the outer surface and the inner surface, a vent constructed to form a vent opening from the inner surface to the outer surface when a vent pressure differential is achieved between an outer surface pressure and an inner surface pressure. The vent is positioned (a) concentric to the electrolyte injection port, and (b) closer to the perimeter edge than the position of the electrolyte injection port.

Abstract: In a transfer device and a process for discrete elements, fed in a line with a predetermined spacing, variations in the dimensions of the discrete elements resulting in a variation in a release spot included in a release segment, are absorbed by an alignment of the receiving elements. A transport device of the transfer device has receiving elements, each configured to receive a respective discrete element and moving along a transport path at a predetermined speed. The discrete elements are transported on a release device of the transfer device along a release path with a linear development. The release path has a release segment intersecting the transport path at a receiving segment of the transport path. The transport device includes a moving mechanism for the receiving elements to align the receiving elements at the receiving segment, where the release segment is superimposed on the transport path at the receiving segment.

Abstract: A movement and filling unit of a container includes a movement and filling equipment. The equipment includes in turn: a frame, a metering member configured to release a filling product through a release opening, a movement device moveably secured to the frame, a housing with at least one seat, secured to the movement device. The movement device is configured to move the at least one seat along a movement trajectory where the following positions are defined: a removal position in which the container is housed in the at least one seat, a filling position in which the at least one seat is vertically aligned at a position under the release opening, and a release position in which the container with the product is removed from the at least one seat.

Abstract: A feed unit for articles includes: a first feeding device; a second feeding device for individually picking up the articles from the first feeding device at a removal location at a predetermined time interval; and a synchronization device for receiving the articles from the first feeding device and to moving the articles into the removal location. A control system is also provided, to adjust the speed of the synchronization device in such a manner that each article reaches the removal location at the predetermined time interval in order to be picked up by the second feeding device.

Abstract: A singling unit for articles stacked in a nested configuration includes at least two stacks of articles stacked in a nested configuration, an extractor group to extract single articles from each stack, and a conveyor to receive the articles singled by the extractor group and to transport them along an advance direction arranged in at least one row substantially parallel to the advance direction. The extractor group is configured to deposit on the conveyor the articles extracted from the stacks in a number of rows smaller than the number of the stacks.

Abstract: A movement unit for articles includes a first carousel device having a first transporter member and first gripping heads mounted thereon and provided to move the articles into a single-row configuration. The movement unit further includes a second carousel device to receive the articles from the first carousel device, having a second transporter member and second gripping heads mounted thereon. Each second gripping head is configured to receive the articles from a respective first gripping head and to move the articles into a multi-row configuration.

Abstract: A support for transporting containers in a microwave inspection device, including a supporting body which can be moved along a feed path and at least two receiving seats connected to the top of the supporting body to be moved along said feed path, wherein said supporting body has two or more supporting portions (S1, S2) which are at least partly separated from each other by one or more openings and each carrying at least one respective receiving seat, said supporting portions (S1, S2) being connected or integral with each other in a lower region of the supporting body.

Abstract: A retention and movement unit of at least one component and at least one container is described. The unit has a moving retention member including, in turn, a frame and a first gripping device with a first retention element, the gripping device having a first configuration for selectively retaining the at least one component by the first retention element. In a first alternative, the first gripping device has a second configuration, different from the first configuration, for selectively retaining the at least one container. In the second alternative, the moving retention member further includes a second gripping device, including a second retention element, the second gripping device having a second configuration, different from the first configuration, for selectively retaining said at least one container.

Abstract: A depalletizing machine for picking up and moving groups of articles, specifically bundles of blanks, includes a containing structure internally provided with at least one receiving area for a movable magazine containing one or more groups of articles. The machine also includes at least one access opening for allowing the magazine to be inserted into, or removed from, the receiving area. The machine also includes a collection zone configured for receiving a succession of groups of articles from the movable magazine and for moving the groups of articles towards the outside of the machine. The machine also includes at least one sensor configured for detecting a position of the movable magazine within the at least one receiving area and a pickup head configured to pick up groups of articles from the movable magazine and transferring them into the collection zone.

Abstract: A method for performing operations on items (A) transported along a manufacturing line including feeding a sequence of items (A) with respective resting portions along a first feed path onto a first transport surface, arranging a gripping assembly having a first gripping head and a second gripping head, picking up a first item (A) from the first feed path using the first gripping head, rotating the first item (A) around a first rotation axis (R1), performing at least one operation on the item (A) during the rotation thereof around the first rotation axis (R1), swapping the positions of the first gripping head and the second gripping head, resting the first item (A) on a second transport surface and releasing the first item (A), and picking up a further item (A) from the first feed path using the second gripping head.

Abstract: The invention provides a method for the improved generation of genetically modified cells in vitro, in order to obtain a population of effector cells with immunotherapeutic activity and methods of using such cells in protocols for adoptive cell therapy. The invention further provides non-viral genetically modified cells, cell populations and cell cultures and the use thereof in the treatment or prevention of diseases and disorders.

Abstract: A magazine for packs of blanks includes a vertical channel configured for inserting and extracting packs of blanks, a succession of groups of supporting parts movable between a retracted position to allow the packs of blanks to move along the channel towards a portion under the supporting part, and an at least partly extracted position, in which the supporting part intercepts a pack of blanks moving down the channel and provides a steady support for the pack of blanks, and transmission means configured to automatically move each supporting part from the retracted position to the at least partly extracted position when the supporting part immediately below it intercepts a respective pack of blanks, thereby defining the steady support.

Abstract: A method for performing operations on items (A) transported along a manufacturing line including feeding a sequence of items (A) with respective resting portions along a first feed path onto a first transport surface, arranging a gripping assembly having a first gripping head and a second gripping head, picking up a first item (A) from the first feed path using the first gripping head, rotating the first item (A) around a first rotation axis (R1), performing at least one operation on the item (A) during the rotation thereof around the first rotation axis (R1), swapping the positions of the first gripping head and the second gripping head, resting the first item (A) on a second transport surface and releasing the first item (A), and picking up a further item (A) from the first feed path using the second gripping head.

Abstract: The present disclosure relates to the drilling of oil wells and more particularly to a testing tool, a testing assembly and method for use in measuring selected rock mechanics characteristics downhole.

Abstract: An inspection device for inspecting containers (100) comprises a rotary conveyor (2), provided with a plurality of receiving cavities (5), and a measuring station (400) configured to inspect each container (100) while the container (100) is being supported and moved by the conveyor (2), wherein the conveyor (2) has continuous motion and the measuring station (400) comprises a microwave detector provided with a measuring zone (410) through which each container (100) passes in order to generate an information item relating to at least one of the following: weight of the container (100) as a whole or of the dose of product contained therein, type of product inside the container (100), presence of foreign bodies in the container (100).

Abstract: A rotary device for welding a continuous web includes a rotary element, support elements for supporting the web, supported by the rotary element, and a plurality of welding units for welding the web. Each welding unit passes from a non-operating position to an operating position and vice versa, and includes a first movement device for commanding a relative rotation of an anvil element relative to a welding tip and a second movement device for moving the anvil element relative to the welding tip such that a contact surface of the anvil element and a contact surface of the welding tip make contact with a portion of the web in a zone between them, and vice versa. First and second drive mechanisms drive the first and second movement devices. The first and second drive mechanisms are configured to vary a positioning of the welding tip relative to the axis.

Abstract: Methods of increasing or enhancing the efficacy of CAR B cell malignancy treatment regimens using immune effector cells (e.g., T cells, NK cells, CIK cells, macrophages) engineered to express chimeric antigen receptors (CAR(s)) that target malignant B cells in combination with antibodies (e.g., monoclonal antibodies, antibody-drug conjugates) that target malignant B cells are provided. Also provided are methods of treating a B cell malignancy in a subject comprising administering to the subject a CAR B cell malignancy treatment regimen and an antibody that targets malignant B cells.

Abstract: A device for processing a continuous web includes a feed station for feeding the web in a feed direction towards a cutting station for cutting the web to a cutting length into individual segments of web that are disc-shaped. A further feed station feeds each segment. A first cutting unit cuts the web into the segments and a second cutting unit includes a cutting element configured to sever the web across a full width in a direction transverse to the feed direction. A drive unit is configured to issue a command to move the cutting element from a non-operating position, where the web is fed by the feed station to the first cutting unit through the second cutting unit, to an operating position, where the web is severed by the cutting element to interrupt feeding of the web to the first cutting unit.