Patents by Inventor Andrea Branch

Andrea Branch has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DETECTION METHODS EMPLOYING HCV CORE LIPID AND DNA BINDING DOMAIN MONOCLONAL ANTIBODIES
    Publication number: 20200033344
    Abstract: The present disclosure provides detection methods employing HCV core lipid binding domain and DNA binding domain monoclonal antibodies or antibody fragments. In certain embodiments, the lipid binding domain monoclonal antibody or antibody fragment recognizes an epitope in amino acids 141 to 161 of HCV core protein and the DNA binding domain antibody or antibody fragment recognizes an epitope in amino acids 95-123 (e.g., in amino acids 99-117) of HCV core protein.
    Type: Application
    Filed: August 13, 2019
    Publication date: January 30, 2020
    Inventors: Robert Ziemann, April Ahlberg, David Hawksworth, Bryan Tieman, A. Scott Muerhoff, Christopher Marohnic, Kathy Otis, Andrea Branch, Francis Eng
  • Detection methods employing HCV core lipid and DNA binding domain monoclonal antibodies
    Patent number: 10444242
    Abstract: The present disclosure provides detection methods employing HCV core lipid binding domain and DNA binding domain monoclonal antibodies or antibody fragments. In certain embodiments, the lipid binding domain monoclonal antibody or antibody fragment recognizes an epitope in amino acids 141 to 161 of HCV core protein and the DNA binding domain antibody or antibody fragment recognizes an epitope in amino acids 95-123 (e.g., in amino acids 99-117) of HCV core protein.
    Type: Grant
    Filed: June 22, 2016
    Date of Patent: October 15, 2019
    Assignees: ABBOTT LABORATORIES, ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
    Inventors: Robert Ziemann, April Ahlberg, David Hawksworth, Bryan Tieman, A. Scott Muerhoff, Christopher Marohnic, Kathy Otis, Andrea Branch, Francis Eng
  • HCV core and minicore binding molecules
    Patent number: 10436789
    Abstract: The present disclosure relates to hepatitis C virus (HCV) core and minicore-binding molecules and nucleic acid sequences encoding such molecules. In particular embodiments, the present invention provides HCV core and minicore-binding molecules (e.g., monoclonal antibodies or antibody fragments) with particular light chain and/or heavy chain CDRs (e.g., selected from SEQ ID NOS: 2-4 and 6-8) and methods for using such molecules to detect the presence of HCV core proteins (e.g., mature p21 core protein or minicore proteins) in a sample.
    Type: Grant
    Filed: December 20, 2018
    Date of Patent: October 8, 2019
    Assignee: Icahn School of Medicine at Mount Sinai
    Inventors: Andrea Branch, Francis Eng
  • HCV CORE AND MINICORE BINDING MOLECULES
    Publication number: 20190170753
    Abstract: The present disclosure relates to hepatitis C virus (HCV) core and minicore-binding molecules and nucleic acid sequences encoding such molecules. In particular embodiments, the present invention provides HCV core and minicore-binding molecules (e.g., monoclonal antibodies or antibody fragments) with particular light chain and/or heavy chain CDRs (e.g., selected from SEQ ID NOS: 2-4 and 6-8) and methods for using such molecules to detect the presence of HCV core proteins (e.g., mature p21 core protein or minicore proteins) in a sample.
    Type: Application
    Filed: December 20, 2018
    Publication date: June 6, 2019
    Applicant: Icahn School of Medicine at Mount Sinai
    Inventors: Andrea BRANCH, Francis ENG
  • DETECTION METHODS EMPLOYING HCV CORE LIPID AND DNA BINDING DOMAIN MONOCLONAL ANTIBODIES
    Publication number: 20170052184
    Abstract: The present disclosure provides detection methods employing HCV core lipid binding domain and DNA binding domain monoclonal antibodies or antibody fragments. In certain embodiments, the lipid binding domain monoclonal antibody or antibody fragment recognizes an epitope in amino acids 141 to 161 of HCV core protein and the DNA binding domain antibody or antibody fragment recognizes an epitope in amino acids 95-123 (e.g., in amino acids 99-117) of HCV core protein.
    Type: Application
    Filed: June 22, 2016
    Publication date: February 23, 2017
    Inventors: ROBERT ZIEMANN, APRIL AHLBERG, DAVID HAWKSWORTH, BRYAN TIEMAN, A. SCOTT MUERHOFF, CHRISTOPHER MAROHNIC, KATHY OTIS, ANDREA BRANCH, FRANCIS ENG
  • Novel hepatitis C virus peptides and uses thereof
    Publication number: 20070280956
    Abstract: Novel hepatitis C virus (HCV) polypeptides are provided which are not encoded by the standard HCV open reading frame. These alternate reading frame polypeptides are useful, inter alia, in vaccine compositions, in diagnosing HCV infection, and as therapeutic targets.
    Type: Application
    Filed: February 20, 2007
    Publication date: December 6, 2007
    Inventors: Andrea Branch, Jose Walewski, Decherd Stump
  • Alternate reading frame polypeptides drived from hepatitis C and methods of their use
    Publication number: 20050202036
    Abstract: Novel hepatitis C virus (HCV) polypeptides are provided which are not encoded by the standard HCV open reading frame. These alternate reading frame polypeptides are useful, inter alia, in vaccine compositions, in diagnosing HCV infection, and as therapeutic targets.
    Type: Application
    Filed: July 22, 2004
    Publication date: September 15, 2005
    Inventors: Andrea Branch, Jose Walewski, Decherd Stump