Patents by Inventor Andrea C. Carrano

Andrea C. Carrano has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20120148565
    Abstract: Ubiquitin ligase wwp-1 and ubiquitin conjugating enzyme ubc-18 are identified in nematodes as mediators of dietary restriction induced longevity and therefore as targets for modulation of lifespan in animals. Methods of screening for compounds that modulate longevity by assaying wwp-1 ubiquitination pathway parameters are provided, as are related systems. In addition, methods of using wwp-1 and/or ubc-18 to modulate longevity or delay onset of age-related diseases are described.
    Type: Application
    Filed: September 23, 2011
    Publication date: June 14, 2012
    Applicant: The Salk Institute for Biological Studies
    Inventors: Andrea C. CARRANO, Andrew DILLIN, Tony HUNTER
  • Patent number: 8058502
    Abstract: Ubiquitin ligase wwp-1 and ubiquitin conjugating enzyme ubc-18 are identified in nematodes as mediators of dietary restriction induced longevity and therefore as targets for modulation of lifespan in animals. Methods of screening for compounds that modulate longevity by assaying wwp-1 ubiquitination pathway parameters are provided, as are related systems. In addition, methods of using wwp-1 and/or ubc-18 to modulate longevity or delay onset of age-related diseases are described.
    Type: Grant
    Filed: August 15, 2008
    Date of Patent: November 15, 2011
    Assignee: The Salk Institute for Biological Studies
    Inventors: Andrea C. Carrano, Andrew Dillin, Tony Hunter
  • Publication number: 20090083868
    Abstract: Ubiquitin ligase wwp-1 and ubiquitin conjugating enzyme ubc-18 are identified in nematodes as mediators of dietary restriction induced longevity and therefore as targets for modulation of lifespan in animals. Methods of screening for compounds that modulate longevity by assaying wwp-1 ubiquitination pathway parameters are provided, as are related systems. In addition, methods of using wwp-1 and/or ubc-18 to modulate longevity or delay onset of age-related diseases are described.
    Type: Application
    Filed: August 15, 2008
    Publication date: March 26, 2009
    Inventors: Andrea C. Carrano, Andrew Dillin, Tony Hunter