Patents by Inventor Andrea Caporale

Andrea Caporale has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Intermediate compounds and derivatives thereof involved in the preparation of 2,4,5-trifluorophenylacetic acid compounds and derivatives thereof
    Patent number: 9238613
    Abstract: Described herein are intermediate compounds and derivatives thereof that can be synthesized during the preparation of 2,4,5-trifluorophenylacetic acid and derivatives thereof.
    Type: Grant
    Filed: August 12, 2014
    Date of Patent: January 19, 2016
    Assignee: F.I.S.—Fabrica Italiana Sintetici S.p.A.
    Inventors: Stefano Tartaggia, Andrea Caporale, Ottorino De Lucchi
  • NEW PROCESS FOR THE PREPARATION OF 2,4,5-TRIFLUOROPHENYLACETIC ACID
    Publication number: 20140350287
    Abstract: The present invention relates to a new process for the preparation of 2,4,5-trifluorophenylacetic acid and salts thereof by means of new synthetic intermediates.
    Type: Application
    Filed: August 12, 2014
    Publication date: November 27, 2014
    Inventors: Stefano Tartaggia, Andrea Caporale, Ottorino De Lucchi
  • Process for the preparation of 2,4,5-trifluorophenylacetic acid
    Patent number: 8835679
    Abstract: The present invention relates to a new process for the preparation of 2,4,5-trifluorophenylacetic acid and salts thereof by new synthetic intermediates.
    Type: Grant
    Filed: January 30, 2013
    Date of Patent: September 16, 2014
    Assignee: F.I.S.—Fabrica Italiana Sintetici S.p.A.
    Inventors: Stefano Tartaggia, Andrea Caporale, Ottorino De Lucchi
  • Process for preparing 1-(6-methylpyridin-3-yl)-2-[4-(methylsulfonyl)phenyl]ethanone, an intermediate of etoricoxib
    Patent number: 8664402
    Abstract: A process for preparing 1-(6-methylpyridin-3-yl)-2-[4-(methyl sulfonyl)phenyl]ethanone, an intermediate of the synthesis of Etoricoxib. The synthesis of the intermediates useful for such preparation is also described.
    Type: Grant
    Filed: January 11, 2012
    Date of Patent: March 4, 2014
    Assignee: F.I.S. Fabbrica Italiana Sintetici S.p.A.
    Inventors: Andrea Castellin, Paolo Stabile, Francesco Fontana, Ottorino De Lucchi, Andrea Caporale, Stefano Tartaggia
  • Method for the preparation of erlotinib
    Patent number: 8609841
    Abstract: An alternative method for the preparation of Erlotinib through a new chemical reaction for the preparation of the 4-(3-aminophenyl)-2-methyl-3-butyn-2-ol key intermediate of formula (IV) according to the following scheme.
    Type: Grant
    Filed: October 13, 2011
    Date of Patent: December 17, 2013
    Assignee: F.I.S. Fabbrica Italiana Sintetici S.p.A.
    Inventors: Andrea Castellin, Ottorino De Lucchi, Andrea Caporale
  • PROCESS FOR PREPARING 1-(6-METHYLPYRIDIN-3-YL)-2-[4-(METHYLSULFONYL)PHENYL]ETHANONE, AN INTERMEDIATE OF ETORICOXIB
    Publication number: 20120232281
    Abstract: A process for preparing 1-(6-methylpyridin-3-yl)-2-[4-(methyl sulfonyl)phenyl]ethanone, an intermediate of the synthesis of Etoricoxib. The synthesis of the intermediates useful for such preparation is also described.
    Type: Application
    Filed: January 11, 2012
    Publication date: September 13, 2012
    Inventors: Andrea Castellin, Paolo Stabile, Francesco Fontana, Ottorino De Lucchi, Andrea Caporale, Stefano Tartaggia
  • METHOD FOR THE PREPARATION OF ERLOTINIB
    Publication number: 20120095228
    Abstract: An alternative method for the preparation of Erlotinib through a new chemical reaction for the preparation of the 4-(3-aminophenyl)-2-methyl-3-butyn-2-ol key intermediate of formula (IV) according to the following scheme.
    Type: Application
    Filed: October 13, 2011
    Publication date: April 19, 2012
    Inventors: Andrea Castellin, Ottorino De Lucchi, Andrea Caporale
  • PTH-like peptides
    Patent number: 7132394
    Abstract: The present invention relates to peptides that are parathyroid hormone (PTH) analogs, useful for the treatment of hypoparathyroidism and diseases characterized by bone mass reduction, such as osteoporosis, and for stimulating bone repair or favoring the engraftment of a bone implant; to the pharmaceutical compositions comprising these PTH-like peptides and use thereof.
    Type: Grant
    Filed: July 19, 2005
    Date of Patent: November 7, 2006
    Assignee: Abiogen Pharma S.p.A.
    Inventors: Andrea Caporale, Nereo Fiori, Elisabetta Schievano, Stefano Mammi, Evaristo Peggion, Michael Chorev, Angela Wittelsberger
  • PTH-like peptides
    Publication number: 20060019902
    Abstract: The present invention relates to peptides that are parathyroid hormone (PTH) analogs, useful for the treatment of hypoparathyroidism and diseases characterized by bone mass reduction, such as osteoporosis, and for stimulating bone repair or favoring the engraftment of a bone implant; to the pharmaceutical compositions comprising these PTH-like peptides and use thereof.
    Type: Application
    Filed: July 19, 2005
    Publication date: January 26, 2006
    Inventors: Andrea Caporale, Nereo Fiori, Elisabetta Schievano, Stefano Mammi, Evaristo Peggion, Michael Chorev, Angela Wittelsberger