Patents by Inventor Andrea Cappelli

Andrea Cappelli has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8546147
    Abstract: The present invention relates to compound of formula I: and their use as chemiluminescent and/or bioluminescent reagents.
    Type: Grant
    Filed: July 12, 2010
    Date of Patent: October 1, 2013
    Assignee: Universita degli Studi di Siena
    Inventors: Germano Giuliani, Andrea Cappelli, Maurizio Anzini, Salvatore Vomero
  • Patent number: 8420634
    Abstract: Amidine, thiourea and guanidine derivatives of appropriately substituted 2-aminobenzothiazoles, 2-amino-3,1-4H-benzothiazines and 3-amino-1,4-3H-benzothiazines, as understood from formula (I), the related pharmaceutically acceptable salts and solvates thereof: and the use of the products and the corresponding pharmaceutical formulations for the treatment of neurodegenerative pathologies such as cerebral ischemia, neurodegeneration induced by cranial trauma, Alzheimer's disease, Multiple Sclerosis and Amyotrophic Lateral Sclerosis.
    Type: Grant
    Filed: September 22, 2008
    Date of Patent: April 16, 2013
    Assignee: Rottapharm S.p.A.
    Inventors: Maurizio Anzini, Antonio Giordani, Francesco Makovec, Andrea Cappelli, Salvatore Vomero, Gianfranco Caselli, Lucio Claudio Rovati
  • Publication number: 20120171703
    Abstract: The present invention relates to compound of formula I: and their use as chemiluminescent and/or bioluminescent reagents.
    Type: Application
    Filed: July 12, 2010
    Publication date: July 5, 2012
    Applicant: UNIVERSITÁ DEGLI STUDI DI SIENA
    Inventors: Germano Giuliani, Andrea Cappelli, Maurizio Anzini, Salvatore Vomero
  • Patent number: 7906551
    Abstract: This invention relates to 3-substituted-1,5-diaryl-2-alkyl-pyrroles of Formula I, pharmaceutical compositions containing them, and to their use for the pharmacological treatment of pain and COX-2 over-activation associated disorders. Compounds of this invention are new pyrrole derivatives bearing in position -3 of the pyrrole ring, several variously functionalized, not aliphatic, side chains which confer to the compounds a relevant COX-2 potency and selectivity along with a remarkable oral efficacy. Phenyl rings in position -1 and -5 are variously substituted, but compounds of particular interest are those substituted in position -5 with 4-methylsulphonyl-phenyl or with 4-aminosulphonyl-phenyl groups.
    Type: Grant
    Filed: August 3, 2006
    Date of Patent: March 15, 2011
    Assignee: Rottapharm S.p.A.
    Inventors: Andrea Cappelli, Maurizio Anzini, Mariangela Biava, Francesco Makovec, Antonio Giordani, Gianfranco Caselli, Lucio Claudio Rovati
  • Publication number: 20100197670
    Abstract: Amidine, thiourea and guanidine derivatives of appropriately substituted 2-aminobenzothiazoles, 2-amino-3,1-4H-benzothiazines and 3-amino-1,4-3H-benzothiazines, as understood from formula (I), the related pharmaceutically acceptable salts and solvates thereof: and the use of the products and the corresponding pharmaceutical formulations for the treatment of neurodegenerative pathologies such as cerebral ischemia, neurodegeneration induced by cranial trauma, Alzheimer's disease, Multiple Sclerosis and Amyotrophic Lateral Sclerosis.
    Type: Application
    Filed: September 22, 2008
    Publication date: August 5, 2010
    Inventors: Maurizio Anzini, Antonio Giordani, Francesco Makovec, Andrea Cappelli, Salvatore Vomero, Gianfranco Caselli, Lucio Claudio Rovati
  • Publication number: 20090264500
    Abstract: This invention relates to 3-substituted-1,5-diaryl-2-alkyl-pyrroles of Formula I, pharmaceutical compositions containing them, and to their use for the pharmacological treatment of pain and COX-2 over-activation associated disorders. Compounds of this invention are new pyrrole derivatives bearing in position-3 of the pyrrole ring, several variously functionalized, not aliphatic, side chains which confer to the compounds a relevant COX-2 potency and selectivity along with a remarkable oral efficacy. Phenyl rings in position-1 and -5 are variously substituted, but compounds of particular interest are those substituted in position-5 with 4-methylsulphonyl-phenyl or with 4-aminosulphonyl-phenyl groups.
    Type: Application
    Filed: August 3, 2006
    Publication date: October 22, 2009
    Inventors: Andrea Cappelli, Maurizio Anzini, Mariangela Biava, Francesco Makovec, Antonio Giordani, Gianfranco Caselli, Lucio Claudio Rovati
  • Patent number: 7225319
    Abstract: A digital embedded architecture, includes a microcontroller and a memory device, suitable for reconfigurable computing in digital signal processing and comprising: a processor, structured to implement a Very Long Instruction Word elaboration mode by a general purpose hardwired computational logic, and an additional data elaboration channel comprising a reconfigurable function unit based on a pipelined array of configurable look-up table based cells controlled by a special purpose control unit, thus easing the elaboration of critical kernels algorithms.
    Type: Grant
    Filed: February 2, 2004
    Date of Patent: May 29, 2007
    Assignee: STMicroelectronics S.r.l.
    Inventors: Fabio Campi, Mario Toma, Andrea Lodi, Andrea Cappelli, Roberto Canegallo, Roberto Guerrieri
  • Patent number: 7193437
    Abstract: An optimized architecture to implement connections between logic blocks and routing lines in reconfigurable gate arrays including connection blocks to connect inputs and outputs of different logic elements by means of connection wires, each connection block including a single line of pass transistor switches; and a decoding stage to drive the pass transistor switch.
    Type: Grant
    Filed: February 13, 2004
    Date of Patent: March 20, 2007
    Assignee: STMicroelectronics S.r.l.
    Inventors: Andrea Cappelli, Luca Ciccarelli, Andrea Lodi, Mario Toma, Fabio Campi
  • Publication number: 20050015573
    Abstract: A digital embedded architecture, includes a microcontroller and a memory device, suitable for reconfigurable computing in digital signal processing and comprising: a processor, structured to implement a Very Long Instruction Word elaboration mode by a general purpose hardwired computational logic, and an additional data elaboration channel comprising a reconfigurable function unit based on a pipelined array of configurable look-up table based cells controlled by a special purpose control unit, thus easing the elaboration of critical kernels algorithms.
    Type: Application
    Filed: February 2, 2004
    Publication date: January 20, 2005
    Inventors: Fabio Campi, Mario Toma, Andrea Lodi, Andrea Cappelli, Roberto Canegallo, Roberto Guerrieri
  • Publication number: 20040225980
    Abstract: An optimised architecture to implement connections between logic blocks and routing lines in reconfigurable gate arrays including connection blocks to connect inputs and outputs of different logic elements by means of connection wires, each connection block including a single line of pass transistor switches; and a decoding stage to drive the pass transistor switch.
    Type: Application
    Filed: February 13, 2004
    Publication date: November 11, 2004
    Applicant: STMicroelectronics S.r.l.
    Inventors: Andrea Cappelli, Luca Ciccarelli, Andrea Lodi, Mario Toma, Fabio Campi
  • Patent number: 6413978
    Abstract: Novel basic derivatives of benz[e]isoindol-1-ones and pyrrolo[3,4-c]quinolin-1-ones which can be represented by the general formula (I) indicated below are described: in which X is CH or N, R is H, Cl or OR1 in which R1 is H or an alkyl group having from 1 to 3 carbon atoms, Het is the 3-endotropyl group (that is, the 8-methyl-8-azadicyclo[3.2.l]oct-3-yl group) or the 3-quinuclidyl group (that is, the 1-azadicyclo[2.2.2]oct-3-yl group); these compounds have been found to be potent and selective antagonists of the 5-HT3 serotonin-like receptor and can therefore be used, for example, as anti-emetics as well as in various pathological conditions of the central nervous system, and as antitussives.
    Type: Grant
    Filed: October 2, 2001
    Date of Patent: July 2, 2002
    Assignee: Rotta Research Laboratorium S.p.A.
    Inventors: Francesco Makovec, Andrea Cappelli, Maurizio Anzini, Salvatore Vomero, Lucio Claudio Rovati
  • Publication number: 20020042426
    Abstract: Novel basic derivatives of benz[e]isoindol-1-ones and pyrrolo[3,4-c]quinolin-1-ones which can be represented by the general formula (I) indicated below are described: 1
    Type: Application
    Filed: October 2, 2001
    Publication date: April 11, 2002
    Applicant: ROTTA RESEARCH LABORATORIUM S.p.A.
    Inventors: Francesco Makovec, Andrea Cappelli, Maurizio Anzini, Salvatore Vomero, Lucio Claudio Rovati
  • Patent number: 6323216
    Abstract: Novel basic derivatives of benz[e]isoindol-1-ones and pyrrolo[3,4-c]quinolin-1-ones which can be represented by the general formula (I) indicated below are described: in which X is CH or N, R is H, Cl or OR1 in which R1 is H or an alkyl group having from 1 to 3 carbon atoms, Het is the 3-endotropyl group (that is, the 8-methyl-8-azadicyclo[3.2.1]oct-3-yl group) or the 3-quinuclidyl group (that is, the 1-azadicyclo[2.2.2]oct-3-yl group); these compounds have been found to be potent and selective antagonists of the 5-HT3 serotonin-like receptor and can therefore be used, for example, as anti-emetics as well as in various pathological conditions of the central nervous system, and as antitussives.
    Type: Grant
    Filed: October 13, 1999
    Date of Patent: November 27, 2001
    Assignee: Rotta Research Laboratorium S.p.A
    Inventors: Francesco Makovec, Andrea Cappelli, Maurizio Anzini, Salvatore Vomero, Lucio Claudio Rovati