Patents by Inventor Andrea Cara

Andrea Cara has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Procedure to block the replication of reverse transcriptase dependent viruses by the use of inhibitors of deoxynucleotides synthesis
    Publication number: 20060154892
    Abstract: A method for inhibiting replication of reverse transcriptase dependent virus in plant or animal cells, comprising the step of administering to said cells a compound that depletes the intracellular pool of deoxyribonucleoside phosphate in an amount effective to inhibit replication of said virus. Hydroxyurea is one such suitable compound. Also disclosed is a method for producing incomplete reverse- transcriptase dependent viral DNA, by administering a deoxyribonucleoside phosphate-depleting drug to cells infected with such a virus.
    Type: Application
    Filed: March 8, 2006
    Publication date: July 13, 2006
    Inventors: Franco Lori, Andrea Cara, Wen-Yi Gao, Robert Gallo
  • Procedure to block the replication of reverse transcriptase dependent viruses by the use of inhibitors of deoxynucleotides synthesis
    Publication number: 20060052317
    Abstract: A method for inhibiting replication of reverse transcriptase dependent virus in plant or animal cells, comprising the step of administering to said cells a compound that depletes the intracellular pool of deoxyribonucleoside phosphate in an amount effective to inhibit replication of said virus. Hydroxyurea is one such suitable compound. Also disclosed is a method for producing incomplete reverse-transcriptase dependent viral DNA, by administering a deoxyribonucleoside phosphate-depleting drug to cells infected with such a virus.
    Type: Application
    Filed: October 14, 2005
    Publication date: March 9, 2006
    Inventors: Franco Lori, Andrea Cara, Wen-Yi Gao, Robert Gallo
  • Vectors for delivering viral and oncogenic inhibitors
    Patent number: 6953687
    Abstract: Cell transformation vectors for inhibiting HIV and tumor growth are provided. Optionally, the vectors encode RNAses such as EDN. Cells transduced by the vectors and methods of transforming cells (in vitro and in vivo) using the vectors are also provided.
    Type: Grant
    Filed: July 17, 1997
    Date of Patent: October 11, 2005
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Susanna Rybak, Andrea Cara, Gabriele Luca Gusella, Dianne Newton
  • Vectors for delivering viral and oncogenic inhibitors
    Publication number: 20050214258
    Abstract: Cell transformation vectors for inhibiting HIV and tumor growth are provided. Optionally, the vectors encode RNAses such as EDN. Cells transduced by the vectors and methods of transforming cells (in vitro and in vivo) using the vectors are also provided.
    Type: Application
    Filed: January 24, 2005
    Publication date: September 29, 2005
    Applicant: The Government of the USA as represented by the Secretary of the Dept. of Health & Human Services
    Inventors: Susanna Rybak, Andrea Cara, Gabriele Gusella, Dianne Newton
  • Procedure to block the replication of reverse transcriptase dependent viruses by the use of inhibitors of deoxynucleotides synthesis
    Publication number: 20010008905
    Abstract: A method for inhibiting replication of reverse transcriptase dependent virus in plant or animal cells, comprising the step of administering to said cells a compound that depletes the intracellular pool of deoxyribonucleoside phosphate in an amount effective to inhibit replication of said virus. Hydroxyurea is one such suitable compound. Also disclosed is a method for producing incomplete reverse- transcriptase dependent viral DNA, by administering a deoxyribonucleoside phosphate-depleting drug to cells infected with such a virus.
    Type: Application
    Filed: January 8, 2001
    Publication date: July 19, 2001
    Inventors: Franco Lori, Andrea Cara, Wen-Yi Gao, Robert C. Gallo
  • Procedure to block the replication of reverse transcriptase dependent viruses by the use of inhibitors of deoxynucleotides synthesis
    Patent number: 6194390
    Abstract: A method for inhibiting replication of reverse transcriptase dependent virus in plant or animal cells, comprising the step of administering to said cells a compound that depletes the intracellular pool of deoxyribonucleoside phosphate in an amount effective to inhibit replication of said virus. Hydroxyurea is one such suitable compound. Also disclosed is a method for producing incomplete reverse-transcriptase dependent viral DNA, by administering a deoxyribonucleoside phosphate-depleting drug to cells infected with such a virus.
    Type: Grant
    Filed: February 3, 2000
    Date of Patent: February 27, 2001
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Franco Lori, Andrea Cara, Wen-Yi Gao, Robert C. Gallo
  • Procedure to block the replication of reverse transcriptase dependent viruses by the use of inhibitors of deoxynucleotides synthesis
    Patent number: 6046175
    Abstract: A method for inhibiting replication of reverse transcriptase dependent virus in plant or animal cells, comprising the step of administering to said cells a compound that depletes the intracellular pool of deoxyribonucleoside phosphate in an amount effective to inhibit replication of said virus. Hydroxyurea is one such suitable compound. Also disclosed is a method for producing incomplete reverse-transcriptase dependent viral DNA, by administering a deoxyribonucleoside phosphate-depleting drug to cells infected with such a virus.
    Type: Grant
    Filed: May 17, 1994
    Date of Patent: April 4, 2000
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Franco Lori, Andrea Cara, Wen-Yi Gao, Robert C. Gallo