Patents by Inventor Andrea Huwiler

Andrea Huwiler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods for the treatment of glomerulonephritis
    Patent number: 9187396
    Abstract: The invention provides compositions and methods for the treatment of glomerulonephritis. In one embodiment, the invention provides a compound of formula (I) R-L-CO—X??(I) (wherein R is a C10-24 unsaturated hydrocarbon group optionally interrupted by one or more heteroatoms or groups of heteroatoms selected from S, O, N, SO, SO2, said hydrocarbon group comprising at least 4 non-conjugated double bonds; L is a linking group forming a bridge of 1 to 5 atoms between the R group and the carbonyl CO; and X is an electron withdrawing group) or a salt thereof for use in the treatment of glomerulonephritis.
    Type: Grant
    Filed: March 7, 2014
    Date of Patent: November 17, 2015
    Assignee: Avexxin AS
    Inventors: Berit Johansen, Andrea Huwiler
  • COMPOSITIONS AND METHODS FOR THE TREATMENT OF GLOMERULONEPHRITIS
    Publication number: 20140256824
    Abstract: The invention provides compositions and methods for the treatment of glomerulonephritis. In one embodiment, the invention provides a compound of formula (I) R-L-CO—X??(I) (wherein R is a C10-24 unsaturated hydrocarbon group optionally interrupted by one or more heteroatoms or groups of heteroatoms selected from S, O, N, SO, SO2, said hydrocarbon group comprising at least 4 non-conjugated double bonds; L is a linking group forming a bridge of 1 to 5 atoms between the R group and the carbonyl CO; and X is an electron withdrawing group) or a salt thereof for use in the treatment of glomerulonephritis.
    Type: Application
    Filed: March 7, 2014
    Publication date: September 11, 2014
    Applicant: AVEXXIN AS
    Inventors: Berit Johansen, Andrea Huwiler
  • Compositions and methods for the treatment of glomerulonephritis
    Patent number: 8796251
    Abstract: The invention provides compositions and methods for the treatment of glomerulonephritis. In one embodiment, the invention provides a compound of formula (I) R-L-CO—X??(I) (wherein R is a C10-24 unsaturated hydrocarbon group optionally interrupted by one or more heteroatoms or groups of heteroatoms selected from S, O, N, SO, SO2, said hydrocarbon group comprising at least 4 non-conjugated double bonds; L is a linking group forming a bridge of 1 to 5 atoms between the R group and the carbonyl CO; and X is an electron withdrawing group) or a salt thereof for use in the treatment of glomerulonephritis.
    Type: Grant
    Filed: June 4, 2010
    Date of Patent: August 5, 2014
    Assignee: Avexxin AS
    Inventors: Berit Johansen, Andrea Huwiler
  • Novel Heterocyclic Compounds as Modulators of Sphingolipid Signaling and Uses Thereof
    Publication number: 20140100248
    Abstract: The present invention relates to new heterocyclic compounds as modulators of sphingolipid signaling and uses thereof of as pharmaceutically active agents, suitable for treating proliferative, degenerative, infectious, and other diseases.
    Type: Application
    Filed: April 2, 2012
    Publication date: April 10, 2014
    Applicants: UNIVERSITÄT BERN, JOHANN WOLFGANG GOETHE-UNIVERSITÄT
    Inventors: Holger Stark, Aleksandra Zivkovic, Andrea Huwiler, Josef Pfeilschifter
  • USE OF PROKARYOTIC SPHINGOSINE-1-PHOSPHATE LYASES AND OF SPHINGOSINE-1-PHOSPHATE LYASES LACKING A TRANSMEMBRANE DOMAIN FOR TREATING HYPERPROLIFERATIVE AND OTHER DISEASES
    Publication number: 20130259851
    Abstract: The present invention relates to the use of prokaryotic sphingosine-1-phosphate lyases (S1PL) and S1PLs that lack a transmembrane domain or of a nucleic acid encoding such an S1PL in the prevention or treatment of a disease condition associated with elevated levels of sphingosine-1-phosphate (S1P), and for which S1P elevation is directly or indirectly causative. In addition, the invention relates to a new product in the form of S1PL lacking the N-terminal loop domain.
    Type: Application
    Filed: November 30, 2011
    Publication date: October 3, 2013
    Applicants: UNIVERSITAT ZURICH, UNIVERSITAT BERN
    Inventors: Uwe Zangemeister-Wittke, Andrea Huwiler, Markus G. Grutter, Florence Bourquin
  • Glomerulonephritis Treatment
    Publication number: 20120136066
    Abstract: A compound of formula (I) R-L-CO—X (I) (wherein R is a C10-24 unsaturated hydrocarbon group optionally interrupted by one or more heteroatoms or groups of heteroatoms selected from S, O, N, SO, SO2, said hydrocarbon group comprising at least 4 non-conjugated double bonds; L is a linking group forming a bridge of 1 to 5 atoms between the R group and the carbonyl CO; and X is an electron withdrawing group) or a salt thereof for use in the treatment of glomerulonephritis.
    Type: Application
    Filed: June 4, 2010
    Publication date: May 31, 2012
    Applicant: AVEXXIN AS
    Inventors: Berit Johansen, Andrea Huwiler
  • COMPOSITIONS AND METHODS FOR THE TREATMENT OF GLOMERULONEPHRITIS
    Publication number: 20100311843
    Abstract: The invention provides compositions and methods for the treatment of glomerulonephritis. In one embodiment, the invention provides a compound of formula (I) R-L-CO—X??(I) (wherein R is a C10-24 unsaturated hydrocarbon group optionally interrupted by one or more heteroatoms or groups of heteroatoms selected from S, O, N, SO, SO2, said hydrocarbon group comprising at least 4 non-conjugated double bonds; L is a linking group forming a bridge of 1 to 5 atoms between the R group and the carbonyl CO; and X is an electron withdrawing group) or a salt thereof for use in the treatment of glomerulonephritis.
    Type: Application
    Filed: June 4, 2010
    Publication date: December 9, 2010
    Applicant: Avexxin AS
    Inventors: Berit Johansen, Andrea Huwiler