Abstract: The present invention relates to methods for determining Alzheimer's Disease (AD) in a patient. Further, the present invention relates to uses of polynucleotides for detecting mi RNAs in a blood sample isolated from a patient for determining Alzheimer's Disease in the patient. Furthermore, the invention relates to kits for determining Alzheimer's Disease in a patient.

Abstract: The invention relates to a method of determining an antimicrobial drug resistance profile for a microorganism, wherein nucleic acid sequences of the microorganism are analyzed for structural variations of the genome comprising at least a change in the genome comprising more than one base, as well as for single nucleotide polymorphisms (SNPs), as well as a method of determining an infection of a patient with a microorganism potentially resistant to antimicrobial drug treatment and a method of selecting a treatment of a patient suffering from an infection with a potentially resistant microorganism, wherein the data of the antimicrobial drug resistance profile are applied.

Abstract: In the case of a strapping apparatus for strapping articles to be packaged with a strapping band, said apparatus having a tensioning device for applying a band tension to a loop of a strapping band, wherein the tensioning device is provided with a tensioning element that is provided to apply a band tension and to engage in the strapping band and is drivable in rotation, and having a connecting device for creating a permanent connection, in particular a welded connection at two regions, located one on top of the other, of the loop of the strapping band, a possibility is intended to be created by way of which damage to articles to be packaged that is attributable to the tensioning operation, and non-uniform applications of tensile stress to a band loop are avoided or at least reduced.

Abstract: An incipient wetness impregnation method for preparing a tin-containing zeolitic material having framework type BEA, a novel tin-containing zeolitic material having framework type BEA and its use.

Abstract: The present invention relates to a process for recovering 3-methylbut-3-en-1-ol from a feed stream F1 comprising 3-methylbut-3-en-1-ol, one or more solvents, water, and isobutene, wherein 3-methylbut-3-en-1-ol, the one or more solvents and water are separated from isobutene by distillation, the process comprising subjecting the feed stream F1 to distillation conditions in a distillation unit, obtaining a bottoms stream B1 which is enriched in -methylbut-3-en-1-ol, in the one or more solvents and in water compared to the feed stream F1 subjec The present invention relates to a process for recovering 3-methylbut-3-en-1-ol from a feed stream F1 comprising 3-methylbut-3-en-1-ol, one or more solvents, water, and isobutene, wherein 3-methylbut-3-en-1-ol, the one or more solvents and water are separated from isobutene by distillation, the process comprising subjecting the feed stream F1 to distillation conditions in a distillation unit, obtaining a bottoms stream B1 which is enriched in -methylbut-3-en-1-ol, in the

Abstract: The present invention relates to non-invasive methods, kits and means for diagnosing and/or prognosing of dilated cardiomyopathy in a body fluid sample from a subject. Further, the present invention relates to set of polynucleotides or sets of primer pairs for detecting sets of miRNAs for diagnosing and/or prognosing of dilated cardiomyopathy in a body fluid sample from a subject. In addition, the present invention relates to sets of miRNAs for diagnosing and/or prognosing of dilated cardiomyopathy in a body fluid sample from a subject.

Abstract: The present invention relates to a method for diagnosing Parkinson's disease (PD) in an individual. Further, the present invention relates to a method for determining the course of Parkinson's disease (PD) in an individual having PD. Furthermore, the present invention relates to a method for determining the risk for developing Parkinson's disease (PD) in an individual. In addition, the present invention relates to the use of at least one polynucleotide for detecting at least one miRNA in a biological sample isolated from an individual for diagnosing Parkinson's disease (PD) in the individual, the use of at least one polynucleotide for detecting at least one miRNA in a biological sample isolated from an individual having Parkinson's disease (PD) for determining the course of PD in the individual, and/or the use of at least one polynucleotide for detecting at least one miRNA in a biological sample isolated from an individual for determining the risk of the individual to develop Parkinson's disease (PD).

Abstract: The present invention relates to a method of removing an RNA fraction with ?200 nucleotides in length from a whole blood sample. The present invention also relates to a method of purifying an RNA fraction with <200 nucleotides in length from a whole blood sample. The present invention further relates to a method of determining the level of RNA molecules with <200 nucleotides in length. In addition, the present invention relates to a method for diagnosing a disease in an individual. Moreover, the present invention relates to a kit which is useful for carrying out the methods of the present invention.

Abstract: The present invention relates to a method of determining markers for a disease from a patient, wherein information from epigenomics and/or the transcriptome from peripheral blood and a diseased tissue or information from epigenomics and the transcriptome from peripheral blood or a diseased tissue is used for obtaining the markers, as well as a method of determining a risk for a disease in a patient using the markers obtained thereby.

Abstract: A mobile strapping device for wrapping material to be packed with a strap. The strapping device includes a modular assembly that includes a display and operating apparatus and at least part of a controller of the strapping device.

Abstract: A holder (10) for detachably fastening a flat, approximately rectangular device such as a tablet computer or a smartphone to a component, in particular to a component of a motor vehicle, wherein the holder includes a holding device (12) for detachably mounting the device and a fastening element (14) connected to the holding device for connecting the holder to the component, wherein a rotary bearing rotatable about an axis of rotation (24) is provided, which is connected to the holding device and wherein a pivot bearing connected to the rotary bearing is provided, which is connected to the fastening element.

Abstract: The present invention relates to methods of determining whether a patient responds to a therapeutic treatment of multiple sclerosis (MS), of monitoring the course of multiple sclerosis (MS) in a patient, of determining the risk for a relapse of multiple sclerosis (MS) in a patient, and of adjusting the dose of a therapeutic drug applied for therapeutic treatment of multiple sclerosis in a patient. Said methods are based on the determination of the level of at least one miRNA in a test sample isolated from the patient. The present invention also relates to a method of identifying a compound suitable for the treatment of multiple sclerosis in a patient.

Abstract: A caliper comprising: (a) an inboard side; (b) an outward side, wherein the inboard side and the outboard side include three or more bores that are radially staggered relative to two or more of the bores; and (c) a pocket located within a central region of the inboard side, the outboard side, or both; wherein the bores on the inboard side, the outboard side, or both are positioned so that: (i) all of the bores are located entirely radially below the pocket; (ii) none of the bores are located below the pocket; (iii) one or more of the bores are located partially radially below the pocket; (iv) one or more of the bores are located entirely radially below the pocket; (v) one or more of the bores are not located partially or entirely radially below the pocket; or (vi) a combination of (iii) through (v).

Abstract: Process for the preparation of alpha, beta unsaturated aldehydes by oxidation of alcohols where the oxidant is oxygen in the presence of a catalyst comprising platinum on a support in the presence of a liquid phase which contains at least 25 weight-% water based on the total weight of the liquid phase.

Abstract: Process for the preparation of alpha, beta unsaturated aldehydes by oxidation of alcohols in the presence of a liquid phase wherein the liquid phase contains 0.1 to less than 25 weight-% water and wherein the liquid phase contains at least 25 weight-% of alcohol(s) of general formula (II) and alpha, beta unsaturated aldehyde(s) of general formula (I) and wherein the oxidant is oxygen and/or hydrogen peroxide.

Abstract: A clamping force measuring instrument for a radial clamping device having at least one force sensor for detecting a clamping force of the clamping device and an evaluation device for evaluating sensor data of the force sensor. The clamping force measuring instrument is embodied as a modular clamping force measuring instrument, having an evaluation module a sensor module. The sensor module includes at least one measurement surface and the force sensor. The evaluation module has a radio interface, a memory and/or a display device. The sensor module and the evaluation module are configured for coupling to one another by a coupling device and each has a data connection device. The data connection devices are connected to one another to produce a data connection in the event of the sensor module being coupled to the evaluation module.

Abstract: The present invention relates to pan-genomes of bacterial species that are stable with regard to their core genome and the addition of new genes, their uses, as well as a data base containing these pan-genomes, a method of determining an antimicrobial drug profile using a pan-genome, a method of determining an infection of a patient and a method of selecting a treatment of a patient using a pan-genome, and a computer program product for carrying out the methods.

Abstract: The invention relates to a retaining device for a still or video camera in the interior of a motor vehicle with a fastening apparatus (5, 5a, 5b, 5c, 5d, 5e) for attaching the retaining device to a vehicle seat part, such as a backrest (2), headrest (3), or headrest holder (4, 4a, 4b) of a vehicle seat (1), and a carrier arm (6, 6?, 6?, 60, 60?, 60?, 62, 62?, 62?) which is oriented approximately horizontally and parallel with respect to the broad side of the backrest (2) and at one end of which a holder (7) is arranged for receiving a camera (8), wherein the carrier arm (6, 6?, 6?, 60, 60?, 60?, 62, 62?, 62?) protrudes beyond the vehicle seat part (2, 3, 4, 4a, 4b) to such an extent that the lens (8a) of the camera (8) has an uninterrupted view towards the front in the driving direction and/or towards the rear in the direction counter to the driving direction, and wherein the carrier arm (6, 6?, 6?, 60, 60?, 60?, 62, 62?, 62?) at its other end is connected via a first rotary joint (6a) with an approximately v

Abstract: The invention relates to a device for suspending objects from a part of a motor vehicle seat, such as a backrest, a headrest, or a headrest mounting of a vehicle seat, comprising a fastening element and a receiving socket for connecting the device to the motor vehicle seat part, and comprising a plug-in element that can be coupled to the receiving socket. At one end, a support arm for suspending the objects is connected to the rear end of the plug-in element by way of a rotary joint having an axis of rotation extending substantially parallel to the broad side of the backrest and/or the headrest, and horizontal, and at the other end, the support arm has an L-shaped hook. In the in-use position, the support arm is oriented such that the longitudinal axis thereof is oriented approximately vertically downwards, and such that the longitudinal axis of the plug-in element includes an angle (?) between approximately 60° and 120°.