Patents by Inventor Andrea Lombardi Borgia

Andrea Lombardi Borgia has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20090163503
    Abstract: Substituted pyrrolo-pyrazole derivatives of formula (I) and pharmaceutically acceptable salts thereof, as defined in the specification, process for their preparation and pharmaceutical compositions comprising them are disclosed; the compounds of the invention may be useful in therapy in the treatment of diseases associated with dysregulated protein kinase activity, like cancer.
    Type: Application
    Filed: December 6, 2006
    Publication date: June 25, 2009
    Applicant: NERVIANO MEDICAL SCIENCES S.R.L.
    Inventors: Tiziano Bandiera, Andrea Lombardi Borgia, Sten Christian Orrenius, Ettore Perrone, Italo Beria, Daniele Fancelli, Arturo Galvani
  • Publication number: 20090136513
    Abstract: A compound having formula (I): wherein: R, A, R1 and R2, are as defined in the specification, and pharmaceutical formulas thereof, and methods of use thereof, as Kinase inhibitors.
    Type: Application
    Filed: March 2, 2007
    Publication date: May 28, 2009
    Applicant: NERVIANO MEDICAL SCIENCES S.R.L
    Inventors: Tiziano Bandiera, Jay Aaron Bertrand, Paolo Pevarello, Ettore Perrone, Andrea Lombardi Borgia, Sten Christian Orrenius, Mauro Angiolini, Daniele Fancelli
  • Publication number: 20090023745
    Abstract: Substituted pyrazolo[4,3-c]pyridine derivatives of formula (I) and pharmaceutically acceptable salts thereof, as defined in the specification, process for their preparation and pharmaceutical compositions comprising them are disclosed; the compounds of the invention may be useful in therapy in the treatment of diseases associated with a dysregulated protein kinase activity, like cancer.
    Type: Application
    Filed: December 6, 2006
    Publication date: January 22, 2009
    Applicant: NERVIANO MEDICAL SCIENCES S.R.L.
    Inventors: Tiziano Bandiera, Andrea Lombardi Borgia, Paolo Polucci, Manuela Villa, Marcella Nesi, Mauro Angiolini, Mario Varasi
  • Patent number: 5859046
    Abstract: Use, in the preparation of a medicament for use in the treatment of multiple sclerosis, of a compound which is a ureido derivative of formula (I) ##STR1## wherein each of m and n, which are the same, is an integer of 1 to 3; and each of the R groups, which are the same, is a naphthyl group substituted by 1 to 3 sulfonic acid groups, or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: October 9, 1997
    Date of Patent: January 12, 1999
    Assignee: Pharmacia & Upjohn S.p.A.
    Inventors: Rachele Alzani, Elena Cozzi, Nicola Mongelli, Andrea Lombardi Borgia, Massimo Temponi, Francesco Colotta
  • Patent number: 5700788
    Abstract: Subject of the present invention are new ureido derivatives of naphthalenephosphonic acids having the following formula (I) ##STR1## wherein each of m and n, which are the same, is an integer of 1 to 4; each of p and q, which are the same, is an integer of 1 to 3; and each of the R groups, which are the same, is a free or esterified phosphonic acid group; and the pharmaceutically acceptable salts thereof.
    Type: Grant
    Filed: October 30, 1995
    Date of Patent: December 23, 1997
    Assignee: Pharmacia & Upjohn S.p.A.
    Inventors: Nicola Mongelli, Angelo Crugnola, Andrea Lombardi Borgia, Enrico Pesenti