Patents by Inventor Andrea Menichetti

Andrea Menichetti has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 1,3-diazo-4-oxa-[3.3.1]-bicyclic derivatives, process for their manufacture and their use as a medicament, in particular for treating diabetes
    Patent number: 10913751
    Abstract: The present invention relates to compounds having structural formula (I) wherein R1 and R2 are defined as set forth in the description. The invention also relates to a process for the manufacture of the above compounds of formula (I), wherein a 4a,7,8,8a-tetrahydropyrido[4,3-e]-1,4,2-dioxazine reacts with a hydride selected from the group consisting of: lithium triethylborohydride (LiBHEt3), sodium triethylborohydride (NaBHEt3), and lithium tetrahydroaluminate (LiAlH4), in the presence of tetrahydrofuran. Furthermore, the invention is aimed at the above compounds of formula (I), or pharmaceutically acceptable salts thereof, for use in medicine, preferably in the treatment of the diabetes and pathologies or conditions correlated thereto.
    Type: Grant
    Filed: May 30, 2018
    Date of Patent: February 9, 2021
    Assignee: UNIVERSITA' DI PISA
    Inventors: Francesco Berti, Mauro Pineschi, Andrea Menichetti
  • 1,3-DIAZO-4-OXA-[3.3.1]-BICYCLIC DERIVATIVES, PROCESS FOR THEIR MANUFACTURE AND THEIR USE AS A MEDICAMENT, IN PARTICULAR FOR TREATING DIABETES
    Publication number: 20200172552
    Abstract: The present invention relates to compounds having structural formula (I) wherein R1 and R2 are defined as set forth in the description. The invention also relates to a process for the manufacture of the above compounds of formula (I), wherein a 4a,7,8,8a-tetrahydropyrido[4,3-e]-1,4,2-dioxazine reacts with a hydride selected from the group consisting of: lithium triethylborohydride (LiBHEt3), sodium triethylborohydride (NaBHEt3), and lithium tetrahydroaluminate (LiAlH4), in the presence of tetrahydrofuran. Furthermore, the invention is aimed at the above compounds of formula (I), or pharmaceutically acceptable salts thereof, for use in medicine, preferably in the treatment of the diabetes and pathologies or conditions correlated thereto.
    Type: Application
    Filed: May 30, 2018
    Publication date: June 4, 2020
    Applicant: UNIVERSITA' DI PISA
    Inventors: Francesco Berti, Mauro Pineschi, Andrea Menichetti