Patents by Inventor Andrea Milenkovic

Andrea Milenkovic has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS FOR USE IN TREATING AUTOSOMAL DOMINANT BEST1-RELATED RETINOPATHIES
    Publication number: 20230313235
    Abstract: The present invention refers to a sgRNA molecule comprising a targeting domain for specifically targeting a SNP in the BEST1 coding region of a pathologic allele, wherein said targeting domain consists of a sequence selected from the group consisting of SEQ ID NO: 3-8, 41-44, 14-20, 50-52 and 54-55, or a sgRNA molecule combination of specifically defined first and second sgRNA molecules, wherein the first and the second sgRNA molecule each comprise a targeting domain for specifically targeting a SNP in the BEST1 gene coding or non-coding region of a pathologic allele. The present invention also refers to a nucleic acid comprising a sequence that encodes the sgRNA molecule or sgRNA molecule combination and to nucleic acid combinations. The present invention further relates to a recombinant adenovirus-associated vims (AAV) comprising the nucleic acids according to the present invention or recombinant AAV combinations.
    Type: Application
    Filed: April 20, 2021
    Publication date: October 5, 2023
    Inventors: Bernhard WEBER, Andrea MILENKOVIC
  • BIOCHANIN A DERIVATIVES FOR TREATMENT OF BEST1-RELATED RETINOPATHIES
    Publication number: 20230149344
    Abstract: The present invention refers to Biochanin A derivative as defined in formula (II) or a salt thereof for use in a method of treating or preventing BEST1-related retinopathies such as autosomal dominant Best vitelliform macular dystrophy. The present invention also refers to a pharmaceutical composition comprising a Biochanin A derivative as defined in formula (II) or a salt thereof and a pharmaceutical acceptable excipient and/or carrier for use in a method of treating or preventing BEST1-related retinopathies such as autosomal dominant Best vitelliform macular dystrophy.
    Type: Application
    Filed: March 30, 2021
    Publication date: May 18, 2023
    Inventors: Bernhard WEBER, Andrea MILENKOVIC, Sabine AMSLINGER, Lisa Marie DÜRR
  • METHOD AND APPARATUS FOR DIAGNOSING AGE-RELATED MACULAR DEGENERATION
    Publication number: 20120196286
    Abstract: Disclosed is a method for identifying an individual who has an altered risk for developing age-related macular degeneration comprising detecting an insertion/deletion polymorphism in the ARMS2 gene
    Type: Application
    Filed: March 28, 2012
    Publication date: August 2, 2012
    Applicant: UNIVERSITY OF REGENSBURG
    Inventors: Bernhard H.F. Weber, Thomas Loenhardt, Andrea Milenkovic, Lars G. Fritsche
  • Method and apparatus for diagnosing age-related macular degeneration
    Patent number: 8168390
    Abstract: Disclosed is a method for identifying an individual who has an altered risk for developing age-related macular degeneration comprising detecting an insertion/deletion polymorphism in the ARMS2 gene.
    Type: Grant
    Filed: May 27, 2009
    Date of Patent: May 1, 2012
    Assignee: University of Regensburg
    Inventors: Bernhard H. F. Weber, Thomas Loenhardt, Andrea Milenkovic, Lars G. Fritsche
  • METHOD AND APPARATUS FOR DIAGNOSING AGE-RELATED MACULAR DEGENERATION
    Publication number: 20100304369
    Abstract: Disclosed is a method for identifying an individual who has an altered risk for developing age-related macular degeneration comprising detecting an insertion/deletion polymorphism in the ARMS2 gene
    Type: Application
    Filed: May 27, 2009
    Publication date: December 2, 2010
    Applicant: UNIVERSITY OF REGENSBURG
    Inventors: Bernhard H.F. Weber, Thomas Loenhardt, Andrea Milenkovic, Lars G. Fritsche