Abstract: The invention relates to a novel, industrial-scale process for the purification of gamma-immunoglobulins (IgG) starting from plasma or fractions thereof. The method involves two chromatographic steps, i.e. a cation exchange capture chromatography, and then a polishing anion exchange chromatography, ensuring a highly purified end product, which contains no aggregates, and high yields. The process also involves a virus inactivation step by means of a solvent/detergent treatment to inactivate the viruses with a lipid envelope, and a virus removal step by nanofiltering to ensure the removal of the non-enveloped viruses.

Abstract: The invention relates to a novel, industrial-scale process for the purification of gamma-immunoglobulins (IgG) starting from plasma or fractions thereof. The method involves two chromatographic steps, i.e. a cation exchange capture chromatography, and then a polishing anion exchange chromatography, ensuring a highly purified end product, which contains no aggregates, and high yields. The process also involves a virus inactivation step by means of a solvent/detergent treatment to inactivate the viruses with a lipid envelope, and a virus removal step by nanofiltering to ensure the removal of the non-enveloped viruses.

Abstract: A polymer for use in an alignment layer for a liquid crystal material is provided. The polymer comprises a polymer backbone comprising a plurality of repeating units, said repeating units being divided into at least two groups, wherein each repeating unit in a first group of said repeating units is functionalized with a pendant sidechain of a first type S1; each repeating unit in a second group of said repeating units is functionalized with a pendant sidechain of a second type S2; said first type of sidechain S1 comprising a fluorine substituted hydrocarbon group; and said second type of sidechain S2 comprising a siloxane. The polymer of the invention promotes homeotropic alignment of liquid crystal materials.