Patents by Inventor Andrea NOLTE
Andrea NOLTE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11916583Abstract: A supply system for at least one orthopedic technology component, which has at least one electronic and/or electrical device and has a supply connection and/or a radio device for receiving data and/or electrical energy. The supply system also includes a holder for the orthopedic technology component, which has a supply device, and which is compatible with the supply connection and/or the radio device, for supplying the orthopedic technology component with data and/or energy. The invention further relates to a system consisting of a supply system and an orthopedic technology device, and to a method for supplying the system with data and/or energy.Type: GrantFiled: December 18, 2018Date of Patent: February 27, 2024Assignee: OTTO BOCK HEALTHCARE PRODUCTS GMBHInventors: Alexander Pappe, Andreas Weigl-Pollack, Erik Albrecht-Laatsch, Michael Nolte, Robert Hoffmann, Robert Kaitan, Luis Sagmeister, Thomas Pauser, Andreas Schramel
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Publication number: 20230190578Abstract: The present invention relates to nanoparticles comprising nucleic acids coated with a (biodegradable) polymer for reversible immobilization and/or controlled release of the nucleic acid comprising nanoparticles. Furthermore, the present invention is directed to medical or diagnostic devices, particularly stents and implants coated by a (biodegradable) polymer with the nucleic acid comprising nanoparticles for reversible immobilization and/or controlled release. Furthermore, the present invention is directed to the use of these nanoparticles coated with a (biodegradable) polymer and to the use of medical devices and implants coated by the (biodegradable) polymer with these nucleic acid comprising nanoparticles in the prophylactic or therapeutic treatment of diseases, particularly in the prevention or treatment of restenosis, calicification, foreign body reaction, or inflammation.Type: ApplicationFiled: October 26, 2022Publication date: June 22, 2023Applicant: CureVac SEInventors: Patrick BAUMHOF, Hans-Peter WENDEL, Andrea NOLTE, Tobias WALKER
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Publication number: 20220249346Abstract: The invention relates to a polyribonucleotide, a cosmetic and pharmaceutical compound that has the polyribonucleotide and a medicinal product that has the polyribonucleotide and the compound.Type: ApplicationFiled: October 5, 2021Publication date: August 11, 2022Applicant: Eberhard Karls Universitaet Tuebingen Medizinische FakultaetInventors: Hans-Peter WENDEL, Timea KELLER, Andrea NOLTE, Meltem AVCI-ADALI, Tobias WALKER
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Patent number: 11330826Abstract: A low-bacteria milk powder with a high WPNI is suggested, which is obtainable by (a) providing a raw milk; (b) heating the raw milk in at least one tubular heat exchanger to a temperature of at least 20° C.; (c) separating the cream, obtaining a skimmed milk; (d) pasteurising the skimmed milk in a tubular heat exchanger for a period from 10 to 60 seconds at a temperature from 72 to 75° C.; (e) evaporating the pasteurised skimmed milk to a dry matter content from 35 to 55% by weight; and (f) drying the pasteurised skimmed milk concentrate in a spray tower.Type: GrantFiled: July 7, 2017Date of Patent: May 17, 2022Assignee: DMK Deutsches Milchkontor GMBHInventors: Thomas Holst, Andreas Nolte
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Publication number: 20180084798Abstract: A low-bacteria milk powder with a high WPNI is suggested, which is obtainable by (a) providing a raw milk; (b) heating the raw milk in at least one tubular heat exchanger to a temperature of at least 20° C.; (c) separating the cream, obtaining a skimmed milk; (d) pasteurising the skimmed milk in a tubular heat exchanger for a period from 10 to 60 seconds at a temperature from 72 to 75° C.; (e) evaporating the pasteurised skimmed milk to a dry matter content from 35 to 55% by weight; and (f) drying the pasteurised skimmed milk concentrate in a spray tower.Type: ApplicationFiled: July 7, 2017Publication date: March 29, 2018Inventors: Thomas Holst, Andreas Nolte
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Publication number: 20170239372Abstract: The present invention relates to nanoparticles comprising nucleic acids coated with a (biodegradable) polymer for reversible immobilization and/or controlled release of the nucleic acid comprising nanoparticles. Furthermore, the present invention is directed to medical or diagnostic devices, particularly stents and implants coated by a (biodegradable) polymer with the nucleic acid comprising nanoparticles for reversible immobilization and/or controlled release. Furthermore, the present invention is directed to the use of these nanoparticles coated with a (biodegradable) polymer and to the use of medical devices and implants coated by the (biodegradable) polymer with these nucleic acid comprising nanoparticles in the prophylactic or therapeutic treatment of diseases, particularly in the prevention or treatment of restenosis, calicification, foreign body reaction, or inflammation.Type: ApplicationFiled: March 6, 2017Publication date: August 24, 2017Applicant: CureVac AGInventors: Patrick BAUMHOF, Hans-Peter WENDEL, Andrea NOLTE, Tobias WALKER
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Publication number: 20170042782Abstract: The invention relates to a polyribonucleotide, a cosmetic and pharmaceutical compound that has the polyribonucleotide and a medicinal product that has the polyribonucleotide and the compound.Type: ApplicationFiled: September 28, 2015Publication date: February 16, 2017Applicant: Eberhard-Karls-Universitaet Tuebingen Medizinische FakultaetInventors: Hans-Peter WENDEL, Timea KELLER, Andrea NOLTE, Meltem AVCI-ADALI, Tobias WALKER
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Publication number: 20150306249Abstract: The present invention relates to nanoparticles comprising nucleic acids coated with a (biodegradable) polymer for reversible immobilization and/or controlled release of the nucleic acid comprising nanoparticles. Furthermore, the present invention is directed to medical or diagnostic devices, particularly stents and implants coated by a (biodegradable) polymer with the nucleic acid comprising nanoparticles for reversible immobilization and/or controlled release. Furthermore, the present invention is directed to the use of these nanoparticles coated with a (biodegradable) polymer and to the use of medical devices and implants coated by the (biodegradable) polymer with these nucleic acid comprising nanoparticles in the prophylactic or therapeutic treatment of diseases, particularly in the prevention or treatment of restenosis, calicification, foreign body reaction, or inflammation.Type: ApplicationFiled: May 25, 2012Publication date: October 29, 2015Applicant: CureVac GmbHInventors: Patrick BAUMHOF, Hans-Peter WENDEL, Andrea NOLTE, Tobias WALKER
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Patent number: 8810906Abstract: The invention relates to an illuminating device for a microscope with an illumination magazine comprising a plurality of light emitting units. A mechanical illuminator changer can change the light emitting unit currently active in the operative position. A filter magazine having a plurality of filter units is present, wherein a mechanical filter changer for changing the filter unit currently in the active operative position is associated with the filter magazine. At least one mechanical coupling component is provided for cooperation with the filter changer and the illuminator and for uniquely assigning each filter unit to a specific light emitting unit.Type: GrantFiled: March 24, 2009Date of Patent: August 19, 2014Assignee: Carl Zeiss MicroImaging GmbHInventors: Leander Dietzsch, Christian Boeker, Andreas Nolte, Thomas Belkner, Michael Wagener
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Patent number: 8304745Abstract: For the microscopy of an object or a specimen with a combination of optical microscopy and particle beam microscopy, an electrically conducting specimen carrier (1) is used which is configured for use in a particle beam microscope as well as in an optical microscope and has at least one alignment mark (2). The alignment mark is configured as a pass-through structure and is detectable from the top and from the bottom of the specimen carrier.Type: GrantFiled: May 31, 2011Date of Patent: November 6, 2012Assignees: Carl Zeiss MicroImaging GmbH, Carl Zeiss AG, Carl Zeiss NTS GmbHInventors: Heino Heise, Andreas Nolte, Christian Thomas, Martin Edelmann, Uwe Wolf, Ulrich Kohlhaas, Dmitry Lysenkov
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Patent number: 8203784Abstract: The invention is directed to a multispectral illumination device for a microscope or for a reader. According to the invention, the illumination device comprises at least three receptacle positions for lighting modules and at least one receptacle position for coupling modules, the mechanical devices for connecting the lighting modules or coupling modules at the receptacle positions to the illumination device being designed in such a way that the lighting modules or coupling modules can be easily changed. Further, the receptacle positions are arranged in such a way that, with suitable selection of the lighting modules and coupling modules, all individual spectra of the lighting modules in a total spectrum are available simultaneously at the output of the illumination device.Type: GrantFiled: October 6, 2007Date of Patent: June 19, 2012Assignee: Carl Zeiss MicroImaging GmbHInventors: Andreas Nolte, Matthias Kramer, Michael Brehm, Christian Boeker
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Publication number: 20120126115Abstract: For the microscopy of an object or a specimen with a combination of optical microscopy and particle beam microscopy, an electrically conducting specimen carrier (1) is used which is configured for use in a particle beam microscope as well as in an optical microscope and has at least one alignment mark (2). The alignment mark is configured as a pass-through structure and is detectable from the top and from the bottom of the specimen carrier.Type: ApplicationFiled: May 31, 2011Publication date: May 24, 2012Inventors: Heino Heise, Andreas Nolte, Christian Thomas, Martin Edelmann, Uwe Wolf, Ulrich Kohlhaas, Dmitry Lysenkov
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Patent number: 8125709Abstract: The present invention is directed to a controllable microscope illumination within a microscope system by which all essential contrasting methods in microscopy can be realized. The illumination device according to the invention comprises a plurality of individual light sources which can be regulated with respect to brightness, wherein these individual light sources are formed as unit cells and form a luminous surface by a periodic arrangement. In an advantageous arrangement, imaging optics are associated with each individual light source in order to magnify the image of the source surface of the individual light source so that the images of the source surfaces of adjacent individual light sources touch. Illumination variants for all of the essential contrasting methods in microscopy can be generated by way of the proposed solution. The proposed LED illumination is electronically switchable, can be regulated with respect to brightness, supplies all colors, is long-lasting and economical.Type: GrantFiled: June 22, 2006Date of Patent: February 28, 2012Assignee: Carl Zeiss MicroImaging GmbHInventors: Lutz Hoering, Andreas Nolte, Michael Brehm, Mario Sondermann
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Patent number: 8040598Abstract: A microscope for observing an object selectably using the bright-field transmitted light contrast procedure or the incident-light fluorescence contrast procedure. During the bright-field transmitted light contrast procedure, an illumination beam path is directed from a bright-field light source to the object and an imaging beam path is directed from the object through the microscope objective into the microscope tube, which includes a fluorescence unit that includes a fluorescence excitation light source, an illumination optical system, a filter set having at least one excitation filter and at least one emission filter, as well as a beamsplitter. The fluorescence unit is mounted movably, so that in a first end position of movement the beamsplitter and the emission filter are out of the imaging beam path of the microscope and in a second end position of movement they are in the imaging beam path between the microscope objective and the microscope tube.Type: GrantFiled: June 12, 2008Date of Patent: October 18, 2011Assignee: Carl Zeiss MicroImaging GmbHInventors: Andreas Nolte, Thomas Bocher, Ingo Fahlbusch
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Patent number: 8004757Abstract: A laser radiation-guiding device including: a laser including a control unit; ports for connection of one module each, it being possible that laser radiation may exit at the ports. The device further can include joining part sensors respectively assigned to a port and whose electrical condition depends on whether a predetermined joining part is spaced apart from the respective port by less than a maximum distance in a predetermined orientation relative to the respective port, and an evaluating unit connected to the joining part sensors via a signal link that detects the electrical conditions of the joining part sensors and, depending on the detected conditions, emits a control signal to the control unit of the laser or to a laser radiation-blocking unit, by which emission of eye-damaging laser radiation to the ports of the device can be prevented inhibited.Type: GrantFiled: September 14, 2005Date of Patent: August 23, 2011Assignee: Carl Zeiss Microimaging GmbHInventors: Andreas Nolte, Hubert Wahl, Klaus Becker
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Publication number: 20110019272Abstract: The invention relates to an illuminating device for a microscope with an illumination magazine comprising a plurality of light emitting units. A mechanical illuminator changer can change the light emitting unit currently active in the operative position. A filter magazine having a plurality of filter units is present, wherein a mechanical filter changer for changing the filter unit currently in the active operative position is associated with the filter magazine. At least one mechanical coupling means is provided for cooperation with the filter changer and the illuminator and for uniquely assigning each filter unit to a specific light emitting unit.Type: ApplicationFiled: March 24, 2009Publication date: January 27, 2011Inventors: Leander Dietzsch, Christian Boeker, Andreas Nolte, Thomas Belkner, Michael Wagener
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Patent number: 7848018Abstract: In an automatic microscope, there is the task to satisfy the demand for an economical, compact structure, especially a miniaturization as an essential aspect. The automatic microscope contains an optical system having the following: an illumination field (1) which is at least approximately arranged in the aperture diaphragm plane (ABE) of a condenser (2) and is used for the illumination of the object; an imaging optic (4); and, an image-providing sensor (5) arranged in the image plane of the imaging optic.Type: GrantFiled: September 30, 2006Date of Patent: December 7, 2010Assignee: Carl Zeiss MicroImaging GmbHInventors: Andreas Nolte, Lutz Höring
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Patent number: 7832894Abstract: The invention relates to an illuminating device for microscopes, wherein the light source has, in particular, a white light illumination having total daylight spectrum and/or an excitation light source for fluorescent colors. The inventive illuminating device for a microscope consists of surface or spatially arranged light sources, which are connected to a control unit for generating any desired illuminating patterns and illuminating spectrums, and an illuminating optic to image these illuminating patterns on the object to be examined. The light sources consist of LEDs (11) which excite at least one luminescence color (14) which is adapted to the wavelength which is emitted by the LEDs (11). The LEDs (11) are arranged concentrically to the optical axis of the illuminating device, preferably, in or in the vicinity of the aperture diaphragm plane.Type: GrantFiled: June 22, 2006Date of Patent: November 16, 2010Assignee: Carl Zeiss MicroImaging GmbHInventors: Günter Rudolph, Jochen Müller, Eva-Maria Menzel, Bryce Anton Moffat, Andreas Nolte
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Publication number: 20100265573Abstract: A laser radiation-guiding device including: a laser including a control unit; ports for connection of one module each, it being possible that laser radiation may exit at the ports. The device further can include joining part sensors respectively assigned to a port and whose electrical condition depends on whether a predetermined joining part is spaced apart from the respective port by less than a maximum distance in a predetermined orientation relative to the respective port, and an evaluating unit connected to the joining part sensors via a signal link that detects the electrical conditions of the joining part sensors and, depending on the detected conditions, emits a control signal to the control unit of the laser or to a laser radiation-blocking unit, by which emission of eye-damaging laser radiation to the ports of the device can be prevented inhibited.Type: ApplicationFiled: September 14, 2005Publication date: October 21, 2010Inventors: Andreas Nolte, Hubert Wahl, Klaus Becker
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Publication number: 20090224694Abstract: The present invention is directed to a controllable microscope illumination within a microscope system by which all essential contrasting methods in microscopy can be realized. The illumination device according to the invention comprises a plurality of individual light sources which can be regulated with respect to brightness, wherein these individual light sources are formed as unit cells and form a luminous surface by a periodic arrangement. In an advantageous arrangement, imaging optics are associated with each individual light source in order to magnify the image of the source surface of the individual light source so that the images of the source surfaces of adjacent individual light sources touch. Illumination variants for all of the essential contrasting methods in microscopy can be generated by means of the proposed solution. The proposed LED illumination is electronically switchable, can be regulated with respect to brightness, supplies all colors, is long-lasting and economical.Type: ApplicationFiled: June 22, 2006Publication date: September 10, 2009Inventors: Lutz Höring, Andreas Nolte, Michael Brehm, Mario Sondermann