Patents by Inventor Andrea PACE

Andrea PACE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SMALL MOLECULES THAT BIND AND/OR MODULATE DIFFERENT FORMS OF TAU OLIGOMERS
    Publication number: 20250388555
    Abstract: The present invention relates to novel small molecules of Formulas I, II, III, Illa, IlIb, and IV and pharmaceutically acceptable salts thereof, as well as the preparation and the use thereof.
    Type: Application
    Filed: June 6, 2025
    Publication date: December 25, 2025
    Applicants: The Board of Regents of The University of Texas System, University of Palermo
    Inventors: Rakez Kayed, Filippa Lo Cascio, Antonio Palumbo Piccionello, Andrea Pace
  • Small molecules that bind and/or modulate differentforms of tau oligomers
    Patent number: 12391657
    Abstract: The present invention relates to novel small molecules of Formulas I, II, III, Ilia, Illb, and IV and pharmaceutically acceptable salts thereof, as well as the preparation and the use thereof.
    Type: Grant
    Filed: April 23, 2020
    Date of Patent: August 19, 2025
    Assignees: The Board of Regents of the University of Texas System, UNIVERSITY OF PALERMO
    Inventors: Rakez Kayed, Filippa Lo Cascio, Antonio Palumbo Piccionello, Andrea Pace
  • OPTIMIZATION FOR DETERMINING AVAILABILITIES
    Publication number: 20250165875
    Abstract: Methods, systems, and computer program products for determining availability computation variation data for the provided time frame. An availability request associated with a travel provider is received from a user device. Future travel information associated with the travel provider is obtained, the future travel information includes one or more attributes. Availability computation data for future departure dates is determined via an availability determination algorithm. Availability computation variation data for the provided time frame is determined. An availability user interface is provided to the user device. The availability user interface may include a graphical display of the availability computation variation data for the provided time frame.
    Type: Application
    Filed: May 24, 2024
    Publication date: May 22, 2025
    Inventors: Pierre FEUILLET, Guillaume GENET, Victoria BOSQ, Gabriele ROMANO, Andrea PACE
  • NOVEL SMALL MOLECULES THAT BIND AND/OR MODULATE DIFFERENTFORMS OF TAU OLIGOMERS
    Publication number: 20220204462
    Abstract: The present invention relates to novel small molecules of Formulas I, II, III, Ilia, Illb, and IV and pharmaceutically acceptable salts thereof, as well as the preparation and the use thereof.
    Type: Application
    Filed: April 23, 2020
    Publication date: June 30, 2022
    Inventors: Rakez Kayed, Filippa Lo Cascio, Antonio Palumbo Piccionello, Andrea Pace
  • Oxadiazole derivatives for the treatment of genetic diseases due to nonsense mutations
    Patent number: 11203578
    Abstract: Are disclosed oxadiazole derivatives, their use as medicaments and in particular for the treatment of diseases associated with the presence of a nonsense mutation in the gene or a premature stop codon in the mRNA, pharmaceutical formulation comprising said oxadiazole derivatives and prodrug or mixture thereof and the methods for the preparation of said Oxadiazole derivatives.
    Type: Grant
    Filed: November 20, 2018
    Date of Patent: December 21, 2021
    Assignees: UNIVERSITA'DEGLI STUDI DIPALERMO, FONDAZIONE PER LA RICERCA SULLA FIBROSI CISTICA—ONLUS
    Inventors: Ivana Pibiri, Andrea Pace, Marco Tutone, Laura Lentini, Raffaella Melfi, Aldo Di Leonardo
  • OXADIAZOLE DERIVATIVES FOR THE TREATMENT OF GENETIC DISEASES DUE TO NONSENSE MUTATIONS
    Publication number: 20210002238
    Abstract: Are disclosed oxadiazole derivatives, their use as medicaments and in particular for the treatment of diseases associated with the presence of a nonsense mutation in the gene or a premature stop codon in the mRNA, pharmaceutical formulation comprising said oxadiazole derivatives and prodrug or mixture thereof and the methods for the preparation of said Oxadiazole derivatives.
    Type: Application
    Filed: November 20, 2018
    Publication date: January 7, 2021
    Applicants: UNIVERSITA' DEGLI STUDI DIPALERMO, FONDAZIONE PER LA RICERCA SULLA FIBROSI CISTICA- ONLUS
    Inventors: Ivana PIBIRI, Andrea PACE, Marco TUTONE, Laura LENTINI, Raffaella MELFI, Aldo DI LEONARDO
  • 1,2,4-Oxadiazol compounds active against gram-positive pathogens
    Patent number: 9920039
    Abstract: The present invention relates to new oxazolidinone compounds of general formula (I) having antibiotic activity even against multiresistant bacterial strains (I).
    Type: Grant
    Filed: March 17, 2014
    Date of Patent: March 20, 2018
    Assignees: UNIVERSITÀ DEGLI STUDI DI MILANO—BICOCCA, ISTITUTO EURO MEDITERRANEO DI SCIENZA E TECNOLOGIA
    Inventors: Rosario Musumeci, Clementina Elvezia Anna Cocuzza, Cosimo Gianluca Fortuna, Andrea Pace, Antonio Palumbo Piccionello
  • 1,2,4-oxadiazol compounds active against gram-positive pathogens
    Patent number: 9862710
    Abstract: The present invention relates to novel oxazolidinone compounds of general formula (I) having antibiotic activity also against multiresistant bacterial strains.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: January 9, 2018
    Assignees: ISTITUTO EURO MEDITERRANEO DI SCIENZA E TECNOLOGIA, UNIVERSITA' DEGLI STUDI DI MILANO—BICOCCA
    Inventors: Rosario Musumeci, Clementina Elvezia Anna Cocuzza, Cosimo Gianluca Fortuna, Andrea Pace, Antonio Palumbo Piccionello
  • NOVEL 1,2,4-OXADIAZOL COMPOUNDS ACTIVE AGAINST GRAM-POSITIVE PATHOGENS
    Publication number: 20160297807
    Abstract: The present invention relates to new oxazolidinone compounds of general formula (I) having antibiotic activity even against multiresistant bacterial strains (I).
    Type: Application
    Filed: March 17, 2014
    Publication date: October 13, 2016
    Inventors: Rosario MUSUMECI, Clementina Elvezia Anna COCUZZA, Cosimo Gianluca FORTUNA, Andrea PACE, Antonio PALUMBO PICCIONELLO