Patents by Inventor Andrea R. Schievella

Andrea R. Schievella has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Novel TNF receptor death domain ligand proteins and inhibitors of ligand binding
    Publication number: 20090092613
    Abstract: Novel TNF receptor death domain (“TNF-R1-DD”) ligand proteins are disclosed. Polynucleotides encoding the TNF-R1-DD ligand protein are also disclosed, along with vectors, host cells, and methods of making the TNF-R1-DD ligand protein. Pharmaceutical compositions containing the TNF-R1-DD ligand protein, methods of treating inflammatory conditions, and methods of inhibiting TNF-R death domain binding are also disclosed. Methods of identifying inhibitors of TNF-R death domain binding and inhibitors identified by such methods are also disclosed.
    Type: Application
    Filed: February 11, 2008
    Publication date: April 9, 2009
    Inventors: Lih-Ling Lin, Jennifer Chen, Andrea R. Schievella, James Graham
  • TNF receptor death domain ligand proteins and inhibitors of ligand binding
    Patent number: 7109307
    Abstract: Novel TNF receptor death domain (“TNF-R1-DD”) ligand proteins are disclosed. Polynucleotides encoding the TNF-R1-DD ligand protein are also disclosed, along with vectors, host cells, and methods of making the TNF-R1-DD ligand protein. Pharmaceutical compositions containing the TNF-R1-DD ligand protein, methods of treating inflammatory conditions, and methods of inhibiting TNF-R death domain binding are also disclosed. Methods of identifying inhibitors of TNF-R death domain binding and inhibitors identified by such methods are also disclosed.
    Type: Grant
    Filed: November 20, 2001
    Date of Patent: September 19, 2006
    Assignee: Genetics Institute, LLC
    Inventors: Lih-Ling Lin, Jennifer Chen, Andrea R. Schievella, James Graham
  • Novel TNF receptor death domain ligand proteins and inhibitors of ligand binding
    Publication number: 20020164716
    Abstract: Novel TNF receptor death domain (“TNF-R1-DD”) ligand proteins are disclosed. Polynucleotides encoding the TNF-R1-DD ligand protein are also disclosed, along with vectors, host cells, and methods of making the TNF-R1-DD ligand protein. Pharmaceutical compositions containing the TNF-R1-DD ligand protein, methods of treating inflammatory conditions, and methods of inhibiting TNF-R death domain binding are also disclosed. Methods of identifying inhibitors of TNF-R death domain binding and inhibitors identified by such methods are also disclosed.
    Type: Application
    Filed: November 20, 2001
    Publication date: November 7, 2002
    Inventors: Lih-Ling Lin, Jennifer Chen, Andrea R. Schievella, James Graham
  • TNF receptor death domain ligand proteins and inhibitors of ligand binding
    Patent number: 6322972
    Abstract: Novel TNF receptor death domain (“TNF-R1-DD”) ligand proteins are disclosed. Polynucleotides encoding the TNF-R1-DD ligand protein are also disclosed, along with vectors, host cells, and methods of making the TNF-R1-DD ligand protein. Pharmaceutical compositions containing the TNF-R1-DD ligand protein, methods of treating inflammatory conditions, and methods of inhibiting TNF-R death domain binding are also disclosed. Methods of identifying inhibitors of TNF-R death domain binding and inhibitors identified by such methods are also disclosed.
    Type: Grant
    Filed: November 2, 1998
    Date of Patent: November 27, 2001
    Assignee: Genetics Institute, Inc.
    Inventors: Lih-Ling Lin, Jennifer Chen, Andrea R. Schievella, James Graham
  • TNF receptor death domain ligand proteins
    Patent number: 5948638
    Abstract: Novel TNF receptor death domain ("TNF-R1-DD") ligand proteins are disclosed. Polynucleotides encoding the TNF-R1-DD ligand protein are also disclosed, along with vectors, host cells, and methods of making the TNF-R1-DD ligand protein. Pharmaceutical compositions containing the TNF-R1-DD ligand protein, methods of treating inflammatory conditions, and methods of inhibiting TNF-R death domain binding are also disclosed. Methods of identifying inhibitors of TNF-R death domain binding and inhibitors identified by such methods are also disclosed.
    Type: Grant
    Filed: April 23, 1997
    Date of Patent: September 7, 1999
    Assignee: Genetics Institute, Inc.
    Inventors: Lih-Ling Lin, Jennifer Chen, Andrea R. Schievella, James Graham
  • TNF receptor death domain ligand proteins
    Patent number: 5891675
    Abstract: Novel TNF receptor death domain ("TNF-R1-DD") ligand proteins are disclosed. Polynucleotides encoding the TNF-R1-DD ligand protein are also disclosed, along with vectors, host cells, and methods of making the TNF-R1-DD ligand protein. Pharmaceutical compositions containing the TNF-R1-DD ligand protein, methods of treating inflammatory conditions, and methods of inhibiting TNF-R death domain binding are also disclosed. Methods of identifying inhibitors of TNF-R death domain binding and inhibitors identified by such methods are also disclosed.
    Type: Grant
    Filed: April 23, 1997
    Date of Patent: April 6, 1999
    Assignee: Genetics Institute, Inc.
    Inventors: Lih-Ling Lin, Jennifer Chen, Andrea R. Schievella, James Graham
  • TNF receptor death ligand proteins and inhibitors of ligand binding
    Patent number: 5852173
    Abstract: Novel TNF receptor death domain ("TNF-R1-DD") ligand proteins are disclosed. Polynucleotides encoding the TNF-R1-DD ligand protein are also disclosed, along with vectors, host cells, and methods of making the TNF-R1-DD ligand protein. Pharmaceutical compositions containing the TNF-R1-DD ligand protein, methods of treating inflammatory conditions, and methods of inhibiting TNF-R death domain binding are also disclosed. Methods of identifying inhibitors of TNF-R death domain binding and inhibitors identified by such methods are also disclosed.
    Type: Grant
    Filed: September 26, 1995
    Date of Patent: December 22, 1998
    Assignee: Genetics Institute, Inc.
    Inventors: Lih-Ling Lin, Jennifer Chen, Andrea R. Schievella, James Graham
  • TNF receptor death domain ligand proteins and method to identify inhibitors of ligand binding
    Patent number: 5849501
    Abstract: Novel TNF receptor death domain ("TNF-R1-DD") ligand proteins are disclosed. Polynucleotides encoding the TNF-R1-DD ligand protein are also disclosed, along with vectors, host cells, and methods of making the TNF-R1-DD ligand protein. Pharmaceutical compositions containing the TNF-R1-DD ligand protein, methods of treating inflammatory conditions, and methods of inhibiting TNF-R death domain binding are also disclosed. Methods of identifying inhibitors of TNF-R death domain binding and inhibitors identified by such methods are also disclosed.
    Type: Grant
    Filed: June 19, 1995
    Date of Patent: December 15, 1998
    Assignee: Genetics Institute, Inc.
    Inventors: Lih-Ling Lin, Jennifer Chen, Andrea R. Schievella
  • TNF receptor death domain ligand proteins and inhibitors of ligand binding
    Patent number: 5843675
    Abstract: Novel TNF receptor death domain ("TNF-R1-DD") ligand proteins are disclosed. Polynucleotides encoding the TNF-R1-DD ligand protein are also disclosed, along with vectors, host cells, and methods of making the TNF-R1-DD ligand protein. Pharmaceutical compositions containing the TNF-R1-DD ligand protein, methods of treating inflammatory conditions, and methods of inhibiting TNF-R death domain binding are also disclosed. Methods of identifying inhibitors of TNF-R death domain binding and inhibitors identified by such methods are also disclosed.
    Type: Grant
    Filed: February 15, 1996
    Date of Patent: December 1, 1998
    Assignee: Genetics Institute, Inc.
    Inventors: Lih-Ling Lin, Jennifer Chen, Andrea R. Schievella, James Graham
  • MADD, a TNF receptor death domain ligand protein
    Patent number: 5712381
    Abstract: Novel TNF receptor death domain ("TNF-R1-DD") ligand proteins are disclosed. Polynucleotides encoding the TNF-R1-DD ligand protein are also disclosed, along with vectors, host cells, and methods of making the TNF-R1-DD ligand protein. Pharmaceutical compositions containing the TNF-R1-DD ligand protein, methods of treating inflammatory conditions, and methods of inhibiting TNF-R death domain binding are also disclosed. Methods of identifying inhibitors of TNF-R death domain binding and inhibitors identified by such methods are also disclosed.
    Type: Grant
    Filed: August 15, 1996
    Date of Patent: January 27, 1998
    Assignee: Genetics Institute, Inc.
    Inventors: Lih-Ling Lin, Jennifer Chen, Andrea R. Schievella, James Graham