Abstract: A computer-implemented method for identifying property changes by analyzing differences between old and new imagery. In one embodiment, an administrator begins by creating a project with links to old and new imagery and uploading a file with parcel boundaries. The application may then divide the project into smaller batches and then automatically classify each batch. Analysts may then review these batches and reject those that are insufficiently accurate. For rejected batches, analysts may manually classify the parcels. Analysts may then review these batches again. In one embodiment, once all batches are accepted, the project may be marked as complete and suitable reports may be generated and sent. These reports may include a customer report which may include overall project statistics, a breakdown of changes by type, a heatmap showing which areas are changing fastest, and/or an estimated tax impact of the identified changes.

Abstract: A computer-implemented method for identifying property changes by analyzing differences between old and new imagery. In one embodiment, an administrator begins by creating a project with links to old and new imagery and uploading a file with parcel boundaries. The application may then divide the project into smaller batches and then automatically classify each batch. Analysts may then review these batches and reject those that are insufficiently accurate. For rejected batches, analysts may manually classify the parcels. Analysts may then review these batches again. In one embodiment, once all batches are accepted, the project may be marked as complete and suitable reports may be generated and sent. These reports may include a customer report which may include overall project statistics, a breakdown of changes by type, a heatmap showing which areas are changing fastest, and/or an estimated tax impact of the identified changes.

Abstract: A computer-implemented method for generating roof reports. In one embodiment, a user begins by entering an address into an application and clicking a “request” button. A 3D model of the structure at the address is prepared. The application may then proceed with manual or automatic roof extraction. For manual roof extraction, an analyst may outline roof facets to create a roof model. For automatic roof extraction, the application may use machine learning or another technique to automatically extract and then simplify roof facets. In either case, the application may then present the roof model to a reviewer for inspection. The reviewer may then accept or reject the roof model. If the reviewer rejects the roof model, an analyst may correct the roof model and resuming it for review. Once the roof model passes a review, the application may then proceed with converting the roof model into a roof report.

Abstract: A computer-implemented method for generating roof reports. In one embodiment, a user begins by entering an address into an application and clicking a “request” button. A 3D model of the structure at the address is prepared. The application may then proceed with manual or automatic roof extraction. For manual roof extraction, an analyst may outline roof facets to create a roof model. For automatic roof extraction, the application may use machine learning or another technique to automatically extract and then simplify roof facets. In either case, the application may then present the roof model to a reviewer for inspection. The reviewer may then accept or reject the roof model. If the reviewer rejects the roof model, an analyst may correct the roof model and resuming it for review. Once the roof model passes a review, the application may then proceed with converting the roof model into a roof report.

Abstract: A computer-implemented method for identifying property changes by analyzing differences between old and new imagery. In one embodiment, an administrator begins by creating a project with links to old and new imagery and uploading a file with parcel boundaries. The application may then divide the project into smaller batches and then automatically classify each batch. Analysts may then review these batches and reject those that are insufficiently accurate. For rejected batches, analysts may manually classify the parcels. Analysts may then review these batches again. In one embodiment, once all batches are accepted, the project may be marked as complete and suitable reports may be generated and sent. These reports may include a customer report which may include overall project statistics, a breakdown of changes by type, a heatmap showing which areas are changing fastest, and/or an estimated tax impact of the identified changes.

Abstract: The present invention relates to methods for forming dicarba bridges in organic compounds. This involves the use of a pair of complementary metathesisable groups on the organic compound, and subjecting the compound to cross-metathesis under microwave radiation conditions. In an alternative, the compounds contain a turn-inducing group between the pair of cross-metathesisable groups to facilitate the cross-metathesis.

Abstract: A method for the synthesis of an amino acid analogue or a salt, solvate, derivative, isomer or tautomer thereof comprising the steps of: (i) subjecting an amino acid containing a metathesisable group to metathesis with a compound containing a complementary metathesisable group of formula (I) or (II): (Formulae (I), (II)) wherein R1 and R2 are independently selected from H and substituted or unsubstituted C1 to C4 alkyl; each R3 is either absent or independently selected from a heteroatom, a substituted or unsubstituted C1 to C20 alkyl, and a substituted or unsubstituted C1 to C20 alkyl group interrupted by one or more heteroatoms; and each X is independently selected from H and an effector molecule; in the presence of a reagent to catalyse the metathesis to form a dicarba bridge between the amino acid containing a metathesisable group and the compound containing a complementary metathesisable group; and (ii) reducing the dicarba bridge to form a saturated dicarba bridge, wherein the reagent used to catalyse s

Abstract: According to the present invention, there is provided a range of new conotoxin derivatives and methods for synthesizing these analogues and other intramolecular dicarba bridge-containing peptides, including dicarba-disulfide bridge-containing peptides.

Abstract: A dicarba analogue of insulin comprising an A-chain and a B-chain or fragments, salts, solvates, derivatives, isomers or tautomers of the A-chain, the B-chain or both, provided that the dicarba analogue is not [A7,B7-(2,7-diaminosuberoyl]-des-(B26-B30)-insulin B25-amide.

Abstract: A method for preparing a peptide or peptides containing a dicarba bridge, comprising: (i) providing a reactable peptide having at least two complementary metathesisable groups or two or more reactable peptides having at least two complementary metathesisable groups between them; (ii) subjecting the reactable peptide or reactable peptides to metathesis to form a reactable peptide or peptides having at least one unsaturated dicarba bridge; and (iii) adding one or more further amino acids to one or both ends of at least one of the reactable peptides.

Abstract: The present invention relates to a controlled metathesis-driven polymerization process which is particularly useful for the synthesis of biological polymers such as peptides and polymers. The invention also provides metathesisable supports, groups and linkers for use in the process.

Abstract: A method, system and device for facilitating the retrieval of a marine anchor from an underwater obstruction, the device being configured to actuate when subjected to a force load of a predetermined peak force threshold to effect a change in the point of retrieval that an anchor rode makes with the anchor. The obstructed anchor may be retrieved from another direction, such as a direction opposite from which the anchor was set.

Abstract: Described herein are methods for forming two or more dicarba bridges, as well as new compounds containing dicarba bridges.

Abstract: A dicarba analogue of insulin comprising an A-chain and a B-chain or fragments, salts, solvates, derivatives, isomers or tautomers of the A-chain, the B-chain or both, provided that the dicarba analogue is not [A7,B7-(2,7-diaminosuberoyl]-des-(B26-B30)-insulin B25-amide.

Abstract: According to the present invention, there is provided a range of new conotoxin derivatives and methods for synthesizing these analogues and other intramolecular dicarba bridge-containing peptides, including dicarba-disulfide bridge-containing peptides.

Abstract: According to the present invention, there is provided a range of new conotoxin derivatives and methods for synthesizing these analogues and other intramolecular dicarba bridge-containing peptides, including dicarba-disulfide bridge-containing peptides.

Abstract: The present invention relates to a controlled metathesis-driven polymerisation process which is particularly useful for the synthesis of biological polymers such as peptides and polymers. The invention also provides metathesisable supports, groups and linkers for use in the process.

Abstract: According to the present invention, there is provided a range of new conotoxin derivatives and methods for synthesizing these analogues and other intramolecular dicarba bridge-containing peptides, including dicarba-disulfide bridge-containing peptides.

Abstract: According to the present invention, there is provided a range of new conotoxin derivatives and methods for synthesizing these analogues and other intramolecular dicarba bridge-containing peptides, including dicarba-disulfide bridge-containing peptides.

Abstract: Described herein are methods for forming two or more dicarba bridges, as well as new compounds containing dicarba bridges.