Patents by Inventor Andrea Scharfe Nugent

Andrea Scharfe Nugent has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Treatment of preterm labor with toll-like receptor 9 antagonists
    Patent number: 8933011
    Abstract: The invention provides a method for treating or preventing preterm labor in pregnant female subjects. The method comprises the step of administering a therapeutically effective amount of a Toll-like Receptor 9 antagonist sufficient to prevent the activation of Toll-like Receptor 9 by fetal DNA. The invention further provides compositions comprising a Toll-like Receptor 9 antagonist for use in the methods of the invention. The compositions and methods of the present invention enhance gestation and therefore improve neonatal morbidity and mortality.
    Type: Grant
    Filed: September 24, 2009
    Date of Patent: January 13, 2015
    Assignees: The Provost, Fellows and Scholars of the College of the Holy and Undivided Trinity of Queen Elizabeth Near Dublin, The Coombe Lying-In Hospital
    Inventors: Luke Anthony O'Neill, John O'Leary, Sean Daly, Andrea Scharfe Nugent
  • COMPOSITION AND METHOD FOR TREATMENT OF PRETERM LABOR
    Publication number: 20110236392
    Abstract: The invention provides a method for treating or preventing preterm labor in pregnant female subjects. The method comprises the step of administering a therapeutically effective amount of a Toll-like Receptor 9 antagonist sufficient to prevent the activation of Toll-like Receptor 9 by fetal DNA. The invention further provides compositions comprising a Toll-like Receptor 9 antagonist for use in the methods of the invention. Said compositions and methods enhance gestation and therefore improve neonatal morbidity and mortality.
    Type: Application
    Filed: September 24, 2009
    Publication date: September 29, 2011
    Inventors: Luke Anthony O'Neill, John O'Leary, Sean Daly, Andrea Scharfe Nugent