Abstract: A fan blade (1) has a front inflow edge (2) and a rear outflow edge (3). The fan blade (1) has an at least partially wavy inflow edge (4) that forms a wave (W) having a specific three-dimensional waveform.

Abstract: The present invention relates to a process for preparing a vegan edible product from edible non-animal proteins which comprises the following steps i to iii.: (i) providing a malleable mass by mixing the following components: a) 7 to 20% by weight, in particular 10 to 18% by weight and especially 13 to 16% by weight, based on the total weight of the malleable mass, of an edible protein component A, which is selected from the group consisting of edible vegetable protein materials, microbial protein materials and mixtures thereof; b) 1 to 3.3% by weight, in particular 1.1 to 2.8% by weight, especially 1.2 to 2.3% by weight, based on the total weight of the malleable mass, of a water-soluble organic polymeric gelling agent which is capable of being gelled by calcium ions as a component B, which is a water-soluble polysaccharide bearing carboxyl groups or a water soluble salt thereof; c) optionally 0.05 to 1% by weight, in particular 0.1 to 0.9% by weight, especially 0.2 to 0.

Abstract: Provided are crystalline forms of a KRAS G12C inhibitor compound and to processes for their preparation. Furthermore, provided is pharmaceutical composition comprising said crystalline forms, and at least one pharmaceutically acceptable excipient. The pharmaceutical composition can be used as a medicament, in particular for the treatment of cancer, and KRAS G12C-mutant cancer.

Abstract: A coating composition comprises a urethane resin, a water absorbent polymer, and a curing agent. The urethane resin is obtained by reaction of an isocyanate reactive compound having multi-epoxide functionality and an isocyanate. When applied to a substrate and thermally cured, the coating composition forms a transparent and smooth coating having permanent anti-fog property.

Abstract: A stator for an electric machine includes: a laminated stator core including stator grooves and having a plug-in side and a bending side, which bending side lies opposite the plug-in side in an axial direction; a stator winding having hairpin elements which are pushed into the stator grooves on the plug-in side of the laminated stator core and bent and electrically connected to the stator winding on the bending side of the laminated stator core; and an end plate which is arranged on the plug-in side in the axial direction between the laminated stator core and the hairpin elements. The hairpin elements are arranged in the axial direction so as to bear against the end plate.

Abstract: A dental apparatus and method, for example an endodontic apparatus and method, is disclosed. The apparatus includes: a supply of fluid; a pump for delivering fluid from the supply under pressure and a handpiece in fluid communication with the pump. The handpiece includes a needle 30, extending from a rearward end proximal to the handpiece to a forward tip distal from the handpiece, a lumen of the needle extending to an opening at the tip to deliver fluid received from the pump to a tooth. The dimensions of the needle and the delivery pressure of the fluid are selected such that the flow of fluid through the needle causes a cloud of inertial cavitation to be formed forward of the needle tip.

Abstract: A fan blade (1) has a front inflow edge (2) and a rear outflow edge (3). The fan blade (1) also has an at least partially wavy inflow edge (4), that forms a wave (W) having a specific three-dimensional waveform.

Abstract: The present invention relates to a process for preparing an edible product, in particular a vegan edible product from edible non-animal proteins which comprises the following steps i. to iv.: i.

Abstract: It relates to a pharmaceutical combination comprising a KRAS G12C inhibitor, in particular 1-{6-[(4M)-4-(5-Chloro-6-methyl-1H-indazol-4-yl)-5-methyl-3-(1-methyl-1H-indazol-5-yl)-1H-pyrazol-1-yl]-2-azaspiro [3.3] heptan-2-yl} prop-2-en-1-one (Compound A) and one or more therapeutically active agents selected from a SHP2 inhibitor (e.g. TNO155) and a PD-1 inhibitor, pharmaceutical compositions comprising the same; and methods of using such combinations and compositions in the treatment or prevention of a cancer or a tumor, in particular wherein the cancer or tumor is KRAS G12C mutated.

Abstract: The present invention relates to a mold for molding a component, in particular a particle foam part and a method for manufacturing the component using such a mold. In one embodiment, a mold for molding a component comprises (a.) a mixture of a polymer material and a filler material, (b.) wherein the filler material is adapted to allow a heating of the component inside the mold by means of an electromagnetic field.

Abstract: In an embodiment an X-ray source includes an electron source configured to emit electrons, an acceleration set-up configured to accelerate the emitted electrons and a transmission window downwards of the acceleration set-up, wherein the transmission window is configured to let through X-rays generated by the accelerated electrons, wherein the transmission window is located either in a straight extension of a line-of-flight of the accelerated electrons or off the line-of-flight and past the acceleration set-up, wherein the transmission window comprises a carbon carrier, and wherein the carbon carrier comprises sp2-hybridized carbon.

Abstract: In at least one embodiment an X-ray source includes an electron source configured to emit electrons, an acceleration set-up configured to accelerate the emitted electrons and a transmission window downwards of the acceleration set-up, the transmission window configured to let through X-rays generated by the accelerated electrons, wherein the transmission window incudes a carbon carrier, and wherein the carbon carrier includes sp2-hybridized carbon.

Abstract: Methods, systems, and devices for techniques for communicating multi-level signals are described. A first device may be configured to communicate signals with a second device according to a modulation scheme. The first device may transmit a first signal to the second device at a first voltage level of the modulation scheme corresponding to a first multi-bit value. The first device may select a second voltage level of the modulation scheme based on a difference between the first voltage level and a third voltage level of the PAM scheme, and may transmit a second signal to the second device at the second voltage level to indicate a second multi-bit value corresponding to the third voltage level. The second device may decode the second signal to determine the second multi-bit value based on receiving the first signal at the first voltage level and the second signal at the second voltage level.

Abstract: A screen plate for a separating device for classifying bulk material along with separating device having at least one screen plate therein classifying bulk material.

Abstract: Enzyme mutant with squalene-hopene-cyclase activity, selected from mutants of a wild-type enzyme comprising an amino acid sequence selected from SEQ-ID No: 1 to 3 or an amino acid sequence derived therefrom with a degree of sequence identity in the range of from 60 to 99.9% of SEQ-ID No. 1 to 3, wherein the mutant catalyzes a one-step monocyclization reaction to produce products such as gamma-dihydroionone and/or alpha-dihydroionone.

Abstract: The present disclosure relates to a modular injection system including a first injection device including a first reservoir unit comprising a reservoir filled with medication, a housing for holding the reservoir and a plunger rod adapted to advance a piston inside the reservoir to dispense the medication and first automatic drive unit releasably attachable to the reservoir unit and including an automatic drive member automatically driven by a power source and adapted to be releasably coupled to the plunger rod. The modular system further comprises a second injection device including a second reservoir unit and a manual drive unit connected to the reservoir unit and including a manual drive member manually driven and connected to a plunger rod of the second reservoir unit. The first and second reservoir unit are identical.

Abstract: Subject-matter of the invention is a screen plate for a separating device for classifying bulk material. The screen plate comprises a profile region having a profile having depressions and elevations extending in a direction of a takeoff side, the profile being describable by a circle arc of a first circle K1 and a circle arc of a second circle K2, and the circles K1 and K2 being disposed adjacent to one another, with the circle arc of the first circle K1 with a radius r1 describing elevations and the circle arc of the second circle K2 with a radius r2 describing the depressions. Each depression undergoes transition, in a takeoff region, into an opening which expands in the direction of the takeoff side, the opening having an opening edge with a width corresponding to the length of the radius r2 to 2*r2.

Abstract: A disposable, single-dose delivery device for self-administration by a patient of a predefined amount or dose of drug from a reservoir through an outlet of the reservoir includes a device operation lock to prevent a delivery operation of the delivery device as shipped to the patient, an embedded electronic control unit with a wireless receiver for receiving an unlock command or message, and an electromechanical actuator for mechanically unlocking the device operation lock and enabling delivery device operation by the patient. The control unit is configured to activate the actuator instantaneously and unconditionally upon receipt of the unlock command. The unlocking mechanism of the delivery device is adapted to be activated from remote in response to a confirmative message indicative of additional double check by a Health Care Professional HCP or expert system.

Abstract: An air vent for a motor vehicle includes a housing with an air channel for feeding air and a partial hemisphere shell. The partial hemisphere shell is mounted in a rotatable manner within the housing such that air fed through the air channel is deflected on the housing before it exits from the air vent.

Abstract: Methods, systems, and devices for activate commands for memory preparation are described. A memory device may receive an activate command for a row of a memory bank in the memory device. The activate command may include an indicator that indicates a type of an access operation associated with the activate command. The memory device may perform, based on the type of the access operation, an operation to prepare the memory device for the access operation. The memory device may then receive an access command for the access operation after performing the operation to prepare the memory device for the access operation.