Abstract: An electric coolant pump may include a valve device controlled at a discharge side by pressure. The valve device may include a coolant inlet, a first coolant outlet, and a second coolant outlet. The valve device may be configured to at least one of open and close at least one of the first coolant outlet and the second coolant outlet based on a selected operating point and a pressure in a coolant.

Abstract: A motor vehicle may include an internal combustion engine, a radiator, a heat exchanger, a coolant pump, and a valve device arranged separately therefrom, which is controlled at an intake side by pressure. The valve device may include at least one first coolant inlet, at least one second coolant inlet, and a coolant outlet connected to an inlet of the coolant pump. The valve device may be configured to, based on a selected operating point of the coolant pump and a pressure in a coolant, at least one of open and close at least one of the at least one first coolant inlet and the at least one second coolant inlet. The at least one first coolant inlet and a coolant outlet of the coolant pump may be connected to the internal combustion engine, and the at least one second coolant inlet may be connected to the radiator.

Abstract: A motor vehicle may include an internal combustion engine, a radiator, a heat exchanger, a coolant pump, and a valve device arranged separately therefrom, which is controlled at an intake side by pressure. The valve device may include at least one first coolant inlet, at least one second coolant inlet, and a coolant outlet connected to an inlet of the coolant pump. The valve device may be configured to, based on a selected operating point of the coolant pump and a pressure in a coolant, at least one of open and close at least one of the at least one first coolant inlet and the at least one second coolant inlet. The at least one first coolant inlet and a coolant outlet of the coolant pump may be connected to the internal combustion engine, and the at least one second coolant inlet may be connected to the radiator.

Abstract: An electric coolant pump may include at least one first coolant inlet, at least one second coolant inlet, a coolant outlet, and a valve device. The valve device may be configured to, based on a selected operating point and a pressure in a coolant, at least one of open and close at least one of the at least one first coolant inlet and the at least one second coolant inlet. The valve device may be integrated in a body of the coolant pump.

Abstract: An electric coolant pump may include a valve device controlled at a discharge side by pressure. The valve device may include a coolant inlet, a first coolant outlet, and a second coolant outlet. The valve device may be configured to at least one of open and close at least one of the first coolant outlet and the second coolant outlet based on a selected operating point and a pressure in a coolant.

Abstract: The invention relates to a stable solid dosage form comprising olmesartan medoxomil and amlodipine or a pharmacologically acceptable salt thereof. In particular, it relates to solid dosage forms free from reducing sugars. The stable solid dosage form may optionally further comprise hydrochlorothiazide or a pharmacologically acceptable salt thereof.

Abstract: A charge air cooler for an internal combustion engine is disclosed. The charge air cooler includes at least one connecting piece for connection to at least one cooling circuit configured to conduct coolant. The charge air cooler includes at least one coolant pump for circulating the coolant. The at least one coolant pump is integrated in at least one flow path within the charge air cooler.

Abstract: A charge air cooler for an internal combustion engine is disclosed. The charge air cooler includes at least one connecting piece for connection to at least one cooling circuit configured to conduct coolant. The charge air cooler includes at least one coolant pump for circulating the coolant. The at least one coolant pump is integrated in at least one flow path within the charge air cooler.

Abstract: The invention relates to a stable solid dosage form comprising olmesartan medoxomil and amlodipine or a pharmacologically acceptable salt thereof. In particular, it relates to solid dosage forms free from reducing sugars. The stable solid dosage form may optionally further comprise hydrochlorothiazide or a pharmacologically acceptable salt thereof.

Abstract: Topically applicable pharmaceutical/therapeutic alcoholic solution compositions, well suited for percutaneous/transdermal antithrombotic therapy, comprise an effective antithrombotic amount of acetylsalicylic acid ("ASA") or salt thereof, formulated into primary alcohol (e.g., isopropanol) and secondary ester (e.g., isopropyl myristate) solvents therefor, optionally in the presence of penetration enhancers and/or ASA hydrolysis inhibitors.

Abstract: The present invention relates to a device for the topical and systemic administration of active substances to or through the skin consisting of a backing layer, at least one self-adhesive layer, and a removable protective layer, wherein the self-adhesive layer consists of(a) 100 parts by weight of a polyacrylate adhesive,(b) 5 to 150, preferably 10 to 100, and in particular 15 to 50 parts by weight of a film former compatible with polyacrylates,(c) 0 to 250 parts by weight of a non-softening active substance and/or adjuvant, and(d) 10 to 250 parts by weight of a softening active substance and/or adjuvant.