Patents by Inventor Andrea Trabocchi

Andrea Trabocchi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 1,2,3-triazole-based peptidomimetic integrin inhibitors for the diagnosis and therapy of tumors
    Patent number: 8809338
    Abstract: The present invention refers to the field of chemical compounds bearing a 1,2,3-triazole ring of formula (I) and possessing guanidino and carboxylic groups or their isosteres, their preparation by Cu-catalyzed “click-chemistry”, and medical-diagnostic use in pathologies where angiogenesis is altered, for example pathologic conditions of tumor origin, tumor metastasis, osteoporosis, and rheumatoid arthritis.
    Type: Grant
    Filed: February 14, 2011
    Date of Patent: August 19, 2014
    Assignee: Universita' Degli Studi di Firenze
    Inventors: Antonio Guarna, Gloria Menchi, Nicoletta Cini, Andrea Trabocchi, Alberto Pupi, Anna Bottoncetti, Silvia Raspanti, Lido Calorini
  • Bicyclic peptidomimetic inhibitors of aspartyl-proteases for the treatment of infectious diseases
    Patent number: 8445484
    Abstract: The present invention refers to 3-aza-bicyclo [3.2.1] octane derivatives of general formula (I) their preparation, use and pharmaceutical compositions useful in the treatment of pathologies associated with microbial pathogens expressing aspartylprotease activity.
    Type: Grant
    Filed: November 24, 2009
    Date of Patent: May 21, 2013
    Assignees: Istituto Superiore di Sanita', Universita' Degli Studi di Firenze
    Inventors: Antonio Cassone, Flavia De Bernardis, Enrico Garaci, Andrea Trabocchi, Antonio Guarna
  • 1,2,3-TRIAZOLE-BASED PEPTIDOMIMETIC INTEGRIN INHIBITORS FOR THE DIAGNOSIS AND THERAPY OF TUMORS
    Publication number: 20130040964
    Abstract: The present invention refers to the field of chemical compounds bearing a 1,2,3-triazole ring of formula (I) and possessing guanidino and carboxylic groups or their isosteres, their preparation by Cu-catalyzed “click-chemistry”, and medical-diagnostic use in pathologies where angiogenesis is altered, for example pathologic conditions of tumor origin, tumor metastasis, osteoporosis, and rheumatoid arthritis.
    Type: Application
    Filed: February 14, 2011
    Publication date: February 14, 2013
    Applicant: UNIVERSITA' DEGLI STUDI DI FIRENZE
    Inventors: Antonio Guarna, Gloria Menchi, Nicoletta Cini, Andrea Trabocchi, Alberto Pupi, Anna Bottoncetti, Silvia Raspanti, Lido Calorini
  • BICYCLIC PEPTIDOMIMETIC INHIBITORS OF ASPARTYL-PROTEASES FOR THE TREATMENT OF INFECTIOUS DISEASES
    Publication number: 20110237577
    Abstract: The present invention refers to 3-aza-bicyclo[3.2.1]octane derivatives of general formula (I) their preparation, use and pharmaceutical compositions useful in the treatment of pathologies associated with microbial pathogens expressing aspartyl-protease activity.
    Type: Application
    Filed: November 24, 2009
    Publication date: September 29, 2011
    Inventors: Antonio Cassone, Flavia De Bernardis, Enrico Garaci, Andrea Trabocchi, Antonio Guarna
  • HETEROCYLIC COMPOUNDS CONTAINING THE MORPHOLINE NUCLEUS THEIR PREPARATION AND USE
    Publication number: 20100087326
    Abstract: Herein are described heterocyclic compounds containing the morpholine nucleus prepared from amino acids, their preparation and use for therapeutic applications.
    Type: Application
    Filed: April 18, 2008
    Publication date: April 8, 2010
    Inventors: Antonio Guarna, Andrea Trabocchi, Gloria Menchi, Claudia Lalli, Filippo Sladojevich, Nicoletta Cini