Patents by Inventor Andrea Velardi

Andrea Velardi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and compositions for increasing the efficiency of therapeutic antibodies using NK cell potentiating compounds
    Patent number: 10059765
    Abstract: The present invention relates, generally, to methods and compositions for increasing the efficiency of therapeutic antibodies. Their efficiency is enhanced through the increase of the ADCC mechanism. More particularly, the invention relates to the use of a therapeutic antibody in combination with compounds that block an inhibitory receptor or stimulate an activating receptor of an NK cell in order to enhance the efficiency of the treatment with therapeutic antibodies in human subjects.
    Type: Grant
    Filed: July 1, 2015
    Date of Patent: August 28, 2018
    Assignee: INNATE PHARMA S.A.
    Inventors: Andrea Velardi, Francois Romagne
  • Methods and Compositions for Increasing the Efficiency of Therapeutic Antibodies Using NK Cell Potentiating Compounds
    Publication number: 20150299319
    Abstract: The present invention relates, generally, to methods and compositions for increasing the efficiency of therapeutic antibodies. Their efficiency is enhanced through the increase of the ADCC mechanism. More particularly, the invention relates to the use of a therapeutic antibody in combination with compounds that block an inhibitory receptor or stimulate an activating receptor of an NK cell in order to enhance the efficiency of the treatment with therapeutic antibodies in human subjects.
    Type: Application
    Filed: July 1, 2015
    Publication date: October 22, 2015
    Inventors: Andrea Velardi, Francois Romagne
  • Methods and compositions for increasing the efficiency of therapeutic antibodies using NK cell potentiating compounds
    Patent number: 9090876
    Abstract: The present invention relates, generally, to methods and compositions for increasing the efficiency of therapeutic antibodies. Their efficiency is enhanced through the increase of the ADCC mechanism. More particularly, the invention relates to the use of a therapeutic antibody in combination with compounds that block an inhibitory receptor or stimulate an activating receptor of an NK cell in order to enhance the efficiency of the treatment with therapeutic antibodies in human subjects.
    Type: Grant
    Filed: July 30, 2010
    Date of Patent: July 28, 2015
    Assignee: INNATE PHARMA S.A.
    Inventors: Andrea Velardi, Francois Romagne
  • Methods and Compositions for Increasing the Efficiency of Therapeutic Antibodies Using NK Cell Potentiating Compounds
    Publication number: 20110008335
    Abstract: The present invention relates, generally, to methods and compositions for increasing the efficiency of therapeutic antibodies. Their efficiency is enhanced through the increase of the ADCC mechanism. More particularly, the invention relates to the use of a therapeutic antibody in combination with compounds that block an inhibitory receptor or stimulate an activating receptor of an NK cell in order to enhance the efficiency of the treatment with therapeutic antibodies in human subjects.
    Type: Application
    Filed: July 30, 2010
    Publication date: January 13, 2011
    Applicant: INNATE PHARMA
    Inventors: Andrea Velardi, Francois Romagne
  • Methods and compositions for increasing the efficiency of therapeutic antibodies using NK cell potentiating compounds
    Patent number: 7803376
    Abstract: The present invention relates, generally, to methods and compositions for increasing the efficiency of therapeutic antibodies. Their efficiency is enhanced through the increase of the ADCC mechanism. More particularly, the invention relates to the use of a therapeutic antibody in combination with compounds that block an inhibitory receptor or stimulate an activating receptor of an NK cell in order to enhance the efficiency of the treatment with therapeutic antibodies in human subjects.
    Type: Grant
    Filed: July 23, 2004
    Date of Patent: September 28, 2010
    Assignee: Innate Pharma S.A.
    Inventors: Andrea Velardi, Francois Romagne
  • Methods and compositions for allogeneic transplantation
    Patent number: 7544355
    Abstract: The present invention relates, generally, to methods and compositions for allogeneic transplantation. More particularly, the invention relates to the use of alloreactive natural killer cells in order to enhance the efficacy and/or safety of allogeneic grafts in human subjects. The invention allows to increase the engraftment of an allogeneic grafts, even in myelo-reductive conditioning, to protect against GVHD and/or to eradicate malignant cells. The invention is particularly suited in allogeneic hematopoietic transplantations, particularly bone marrow transplantations.
    Type: Grant
    Filed: March 11, 2003
    Date of Patent: June 9, 2009
    Assignee: Universita Degli Studi di Perugia
    Inventor: Andrea Velardi
  • Methods and compositions for increasing the efficiency of therapeutic antibodies using alloreactive natural killer cells
    Publication number: 20060240005
    Abstract: The present invention relates, generally, to methods and compositions for increasing the efficiency of therapeutic antibodies. Their efficiency is enhanced through the increase of the ADCC mechanism. More particularly, the invention relates to the use of a therapeutic antibody in combination with alloreactive natural killer cells in order to enhance the efficiency of the treatment with therapeutic antibody in human subjects.
    Type: Application
    Filed: July 23, 2004
    Publication date: October 26, 2006
    Applicant: Universita Degli Studi di Perugia
    Inventor: Andréa Velardi
  • Methods and compositions for increasing the efficiency of therapeutic antibodies using NK cell potentiating compounds
    Publication number: 20050037002
    Abstract: The present invention relates, generally, to methods and compositions for increasing the efficiency of therapeutic antibodies. Their efficiency is enhanced through the increase of the ADCC mechanism. More particularly, the invention relates to the use of a therapeutic antibody in combination with compounds that block an inhibitory receptor or stimulate an activating receptor of an NK cell in order to enhance the efficiency of the treatment with therapeutic antibodies in human subjects.
    Type: Application
    Filed: July 23, 2004
    Publication date: February 17, 2005
    Applicants: Universita degli studi di Perugia, Innate Pharma
    Inventors: Andrea Velardi, Francois Romagne
  • Methods and compositions for allogeneic transplantation
    Publication number: 20040019390
    Abstract: The present invention relates, generally, to methods and compositions for allogeneic transplantation. More particularly, the invention relates to the use of alloreactive natural killer cells in order to enhance the efficacy and/or safety of allogeneic grafts in human subjects. The invention allows to increase the engraftment of an allogeneic grafts, even in myelo-reductive conditioning, to protect against GVHD and/or to eradicate malignant cells. The invention is particularly suited in allogeneic hematopoietic transplantations, particularly bone marrow transplantations.
    Type: Application
    Filed: March 11, 2003
    Publication date: January 29, 2004
    Inventor: Andrea Velardi