Patents by Inventor Andrea Y. Thompson

Andrea Y. Thompson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cross-linked polysaccharide drug carrier
    Patent number: 6953784
    Abstract: A carrier and a method for preparing it are provided for use in the delivery of therapeutic agents. A polysaccharide is reacted with an oxidizing agent to open sugar rings on the polysaccharide to form aldehyde groups. The aldehyde groups are reacted to form covalent oxime linkages with a second polysaccharide and each of the first and second polysaccharide is selected from the group consisting of hyaluronic acid, dextran, dextran sulfate, chondroitin sulfate, dermatan sulfate, keratan sulfate, heparan, heparan sulfate and alginate.
    Type: Grant
    Filed: October 3, 2003
    Date of Patent: October 11, 2005
    Assignee: Depuy Spine, Inc.
    Inventors: Andrea Y. Thompson, Lin Shu Liu, Robert C. Spiro
  • Cross-linked polysaccharide drug carrier
    Publication number: 20040077592
    Abstract: A carrier and a method for preparing it are provided for use in the delivery of therapeutic agents. A polysaccharide is reacted with an oxidizing agent to open sugar rings on the polysaccharide to form aldehyde groups. The aldehyde groups are reacted to form covalent oxime linkages with a second polysaccharide and each of the first and second polysaccharide is selected from the group consisting of hyaluronic acid, dextran, dextran sulfate, chondroitin sulfate, dermatan sulfate, keratan sulfate, heparan, heparan sulfate and alginate.
    Type: Application
    Filed: October 3, 2003
    Publication date: April 22, 2004
    Inventors: Andrea Y. Thompson, Lin Shu Liu, Robert C. Spiro
  • Cross-linked polysaccharide drug carrier
    Patent number: 6683064
    Abstract: A carrier and a method for preparing it are provided for use in the delivery of therapeutic agents. A polysaccharide is reacted with an oxidizing agent to open sugar rings on the polysaccharide to form aldehyde groups. The aldehyde groups are reacted to form covalent oxime linkages with a second polysaccharide and each of the first and second polysaccharide is selected from the group consisting of hyaluronic acid, dextran, dextran sulfate, chondroitin sulfate, dermatan sulfate, keratan sulfate, heparan, heparan sulfate and alginate.
    Type: Grant
    Filed: September 17, 2001
    Date of Patent: January 27, 2004
    Assignee: DePuy Acromed, Inc.
    Inventors: Andrea Y. Thompson, Lin Shu Liu, Robert C. Spiro
  • Cross-linked polysaccharide drug carrier
    Publication number: 20030012765
    Abstract: A carrier and a method for preparing it are provided for use in the delivery of therapeutic agents. A polysaccharide is reacted with an oxidizing agent to open sugar rings on the polysaccharide to form aldehyde groups. The aldehyde groups are reacted to form covalent oxime linkages with a second polysaccharide and each of the first and second polysaccharide is selected from the group consisting of hyaluronic acid, dextran, dextran sulfate, chondroitin sulfate, dermatan sulfate, keratan sulfate, heparan, heparan sulfate and alginate.
    Type: Application
    Filed: September 17, 2001
    Publication date: January 16, 2003
    Inventors: Andrea Y. Thompson, Lin Shu Liu, Robert C. Spiro
  • Cross-linked polysaccharide drug carrier
    Patent number: 6303585
    Abstract: A carrier and a method for preparing it are provided for use in the delivery of therapeutic agents. A polysaccharide is reacted with an oxidizing agent to open sugar rings on the polysaccharide to form aldehyde groups. The aldehyde groups are reacted to form covalent oxime linkages with a second polysaccharide and each of the first and second polysaccharide is selected from the group consisting of hyaluronic acid, dextran, dextran sulfate, chondroitin sulfate, dermatan sulfate, keratan sulfate, heparan, heparan sulfate and alginate.
    Type: Grant
    Filed: July 1, 1998
    Date of Patent: October 16, 2001
    Assignee: Orquest, Inc.
    Inventors: Robert C. Spiro, Andrea Y. Thompson, LinShu Liu
  • Method and activin compositions for inducing bone growth
    Patent number: 5413989
    Abstract: Activin is administered systemically and locally to induce the growth of mature bone. Activin enhances the level of bone formation and the quality of the bone formed when administered locally with BMP or bone marrow. Administration of activin by subcutaneous route promotes systemic increase in the bone mass.
    Type: Grant
    Filed: May 3, 1993
    Date of Patent: May 9, 1995
    Assignee: Celtrix Pharmaceuticals, Inc.
    Inventors: Yasushi Ogawa, David K. Schmidt, Rosa Armstrong, Ranga Nathan, Andrea Y. Thompson, Saeid M. Seyedin
  • Use of bone morphogenetic protein in synergistic combination with TGF-.beta. for bone repair
    Patent number: 5393739
    Abstract: Bone morphogenetic proteins -2 and -3 (BMPs -2 and -3) work in synergistic combination with TGF-.beta.z to provide compositions with increased osteogenic activity. Methods of treating bone defects, inducing bone growth and increasing bone marrow cell production using these compositions are also disclosed.
    Type: Grant
    Filed: September 15, 1993
    Date of Patent: February 28, 1995
    Assignee: Celtrix Pharmaceuticals, Inc.
    Inventors: Hanne Bentz, Andrea Y. Thompson, Rosa Armstrong, David M. Rosen
  • Method for inducing bone growth
    Patent number: 5208219
    Abstract: Activin is administered systemically and locally to induce the growth of mature bone. Activin enhances the level of bone formation and the quality of the bone formed when administered locally with BMP or bone marrow. Administration of activin by subcutaneous route promotes systemic increase in the bone mass.
    Type: Grant
    Filed: February 14, 1991
    Date of Patent: May 4, 1993
    Assignee: Celtrix Pharmaceuticals Inc.
    Inventors: Yasushi Ogawa, David K. Schmidt, Rosa Armstrong, Ranga Nathan, Andrea Y. Thompson, Saeid M. Seyedin