Patents by Inventor Andrea Zistler

Andrea Zistler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation and resolution of mandelic acid derivatives
    Patent number: 7960582
    Abstract: The present invention relates to a new process for the resolution of mandelic acid derivatives from racemic mandelic acid derivative mixtures by salt formation with chiral base cyclic amides; to the resolved mandelic acid cyclic amide salts (see, for example, formula IIa), as well as certain other metal and amine salts of the mandelic acid derivatives, and to the use of the resolved mandelic acid derivatives as intermediates suitable for large-scale manufacturing of, for example, pharmaceutical compounds; Formula IIa, wherein R is selected from CHF2, H, C1-6 Alkyl, CH2F, CHCl2 and CClF2; and wherein n is 0, 1 or 2; R1 is H or C1-6 Alkyl and X is H, halo or C1-6 Alkyl.
    Type: Grant
    Filed: November 25, 2004
    Date of Patent: June 14, 2011
    Assignee: AstraZeneca AB
    Inventors: Hans Jorgen Blixt, Bo Lars Gustaf Bosson, Roberto Guiseppe Paolo Gatti, Simone Zaramella, Michael William Senior, Kurt Vogtli, Andrea Zistler
  • Process
    Publication number: 20080312457
    Abstract: The present invention relates to a new process for the resolution of mandelic acid derivatives from racemic mandelic acid derivative mixtures by salt formation with chiral base cyclic amides; to the resolved mandelic acid cyclic amide salts (see, for example, formula IIa), as well as certain other metal and amine salts of the mandelic acid derivatives, and to the use of the resolved mandelic acid derivatives as intermediates suitable for large-scale manufacturing of, for example, pharmaceutical compounds; Formula IIa, wherein R is selected from CHF2, H, C1-6 Alkyl, CH2F, CHCl2 and CClF2; and wherein n is 0, 1 or 2; R1 is H or C1-6 Alkyl and X is H, halo or C1-6 Alkyl.
    Type: Application
    Filed: November 25, 2004
    Publication date: December 18, 2008
    Inventors: Hans Jorgen Blixt, Bo Lars Gustaf Bosson, Roberto Guiseppe Paolo Gatti, Simone Zaramella, Michael William Senior, Kurt Vogtli, Andrea Zistler