Abstract: The present invention relates to oligomeric compounds comprising at least two peptide moieties that bind specifically to proteoglycans, their payload conjugates and pharmaceutical compositions containing the same. Instant compounds, payload conjugates and pharmaceutical compositions are particularly useful in the treatment of cancer and in diagnostics.

Abstract: An opening system for a building wall includes a peripheral frame, a mullion, a pair of frameworks disposed in an empty space of the peripheral frame, a plurality of hinges swingable mounting the frameworks to the peripheral frame within the empty space, and a pair of latching assemblies. The latching assemblies having transversely-extending latch mechanisms that are disposed in respective ones of the frameworks and axially offset from one another so that one of latch mechanisms of one of the frameworks is latchably engageable with a portion of an adjacent one of the lateral sides of the mullion and the other one of the latch mechanisms of the other of the frameworks is latchably engageable with an adjacent portion of the one of the frameworks being located past the rear side of the mullion.

Abstract: Modular furnishing elements constituted by a single piece or by a plurality of pieces, provided with a plurality of internal intrusions of air and, in a lower region, with an opaque region. The transparent pieces are mutually adjacent so as to define at least one gap at which one or more ribbons with LEDs are embedded or associated. The light, in passing through the piece, is refracted through the intrusions thus illuminating the pieces.