Patents by Inventor Andreas A. Kapsalis

Andreas A. Kapsalis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of quantitative enzyme determination
    Patent number: 5612178
    Abstract: Methods and kits are provided for the quantitative determination of the presence of an enzyme analyte in a sample by determination of the rate of analyte catalyzed reaction on a chromatographic medium. The methods may be used to determine both steady state and non-steady state enzyme reaction kinetics and provide a physical record reflecting the same. In a preferred embodiment, an analyte enzyme in a sample to be analyzed is immobilized at a reaction site on a chromatographic medium, the chromatographic medium is contacted with a solution containing a substrate, the solution is transported on the chromatographic medium to the reaction site where the analyte enzyme catalyzes the reaction of the substrate to produce a detectable reaction product at a rate related to the amount of enzyme present, and the solution and reaction product are transported from the reaction site to a detection region formed by a length of the chromatographic medium downstream from the reaction site.
    Type: Grant
    Filed: August 24, 1992
    Date of Patent: March 18, 1997
    Assignee: Abbott Laboratories
    Inventors: Julian Gordon, Andreas A. Kapsalis, Richard E. Thompson
  • Multilayer solid phase immunoassay support and method of use
    Patent number: 5120662
    Abstract: An immunoassay which is capable of simultaneously detecting any desired number of antigens of one infectious agent, or combinations of antigens of several infectious agents, or any desired number of immunoglobulins of one infectious agent, or combinations of immunoglobulins of several infectious agents on a single solid support. A test sample is contacted with a solid support on which one or more antigens are immobilized as discrete test sites. Antigen-antibody complexes are formed and detected on the solid support.
    Type: Grant
    Filed: June 4, 1990
    Date of Patent: June 9, 1992
    Assignee: Abbott Laboratories
    Inventors: Emerson W. Chan, Werner Schulze, William G. Robey, Brian P. Braun, Cynthia K. Daluga, Andreas A. Kapsalis, Kevin M. Knigge, John E. Stephens, Joseph J. Stojak, II, David S. Vallaris, Benton A. Durley, deceased, James D. Defreese, Carl W. Merkh
  • Method of detecting antigens or antibodies
    Patent number: 3949064
    Abstract: This disclosure concerns a solid phase method for detecting antigens or antibodies. An unknown sample is contacted with two sources of solid phase antigen. By treating each source in a particular manner it is possible to determine if the sample contains antigen or antibody.
    Type: Grant
    Filed: October 26, 1973
    Date of Patent: April 6, 1976
    Assignee: Baxter Laboratories, Inc.
    Inventors: Irene Bornstein, Andreas A. Kapsalis
  • Method of detecting antigens or antibodies
    Patent number: RE29955
    Abstract: This disclosure concerns a solid phase method for detecting antigens or antibodies. An unknown sample is contacted with two sources of solid phase antigen. By treating each source in a particular manner it is possible to determine if the sample contains antigen or antibody.
    Type: Grant
    Filed: March 13, 1978
    Date of Patent: April 3, 1979
    Assignee: Baxter Travenol Laboratories, Inc.
    Inventors: Irene Bornstein, Andreas A. Kapsalis