Abstract: Systems, computer program products, and methods are described herein for combinatorial data outlier detection via database query statement generation. A table comprising rows and columns is received, wherein each column comprises records and a corresponding data element. A datatype to be assigned to each data element is determined, based on each column and using a first machine learning model. Conditions are generated for columns corresponding to each data element. The conditions are combined into a predetermined number of condition combinations, wherein the condition combinations comprise combinatorial sequencing of the conditions. A query statement is generated for each of the condition combinations. The table in queried with each query statement to determine query results. A data element quantity and a record quantity in the query results are determined for each query statement.

Abstract: The invention relates to a collapsible ring made of several side walls (15, 16) for a transportation container (11), which is positioned to stand on a palette base (12) of a transportation palette (13) and surrounds an interior (19) delimited by the side walls (15, 16), and at least one intermediate base (31) that can be arranged in the ring (14) in a usage position (32) and having at least one releasable connection (34) formed between the side wall (15, 16) and the intermediate base (31), said connection being formed by at least one holding element (36), wherein adjacent and/or opposing side walls (15, 16) are held by the releasable connection (34) at a distance to the intermediate base (31), and the intermediate base (31) is simultaneously positioned by the releasable connection (34) to the usage position (32) in relation to the adjacent side wall.

Abstract: The present invention relates to novel aminoglycoside compounds having antimicrobial properties and being suitable, for example, as therapeutic agents for use in the treatment of mammalian disease and in particular to novel therapeutic agents suitable for use in the treatment of microbial infection in mammals. The present invention further relates to the use of pharmaceutical compositions comprising said agents in the treatment of medical conditions in mammals, in particular in the treatment of microbial infection. The agents and pharmaceutical compositions of the invention are of particular relevance in the treatment of diseases associated with antibiotic-resistant microbes. The invention further relates to compounds for use in the treatment of diseases whose treatment is made otherwise difficult due to antibiotic-class-related bacterial resistance and provides novel therapeutic agents suitable for use in the treatment of multidrug-resistant (MDR) infections.

Abstract: An apparatus for producing metal organic frameworks, comprising: a tubular flow reactor comprising a tubular body into which, in use, precursor compounds which form the metal organic framework are fed and flow, said tubular body including at least one annular loop.

Abstract: The invention relates to a collapsible ring made of several side walls (15, 16) for a transportation container (11), which is positioned to stand on a palette base (12) of a transportation palette (13) and surrounds an interior (19) delimited by the side walls (15, 16), and at least one intermediate base (31) that can be arranged in the ring (14) in a usage position (32) and having at least one releasable connection (34) formed between the side wall (15, 16) and the intermediate base (31), said connection being formed by at least one holding element (36), wherein adjacent and/or opposing side walls (15, 16) are held by the releasable connection (34) at a distance to the intermediate base (31), and the intermediate base (31) is simultaneously positioned by the releasable connection (34) to the usage position (32) in relation to the adjacent side wall.

Abstract: An apparatus for producing metal organic frameworks, comprising: a tubular flow reactor comprising a tubular body into which, in use, precursor compounds which form the metal organic framework are fed and flow, said tubular body including at least one annular loop.

Abstract: An apparatus for producing metal organic frameworks, comprising: a tubular flow reactor comprising a tubular body into which, in use, precursor compounds which form the metal organic framework are fed and flow, said tubular body including at least one annular loop.

Abstract: An apparatus for producing metal organic frameworks, comprising: a tubular flow reactor comprising a tubular body into which, in use, precursor compounds which form the metal organic framework are fed and flow, said tubular body including at least one annular loop.

Abstract: An apparatus for producing metal organic frameworks, comprising: a tubular flow reactor comprising a tubular body into which, in use, precursor compounds which form the metal organic framework are fed and flow, said tubular body including at least one annular loop.

Abstract: A train loading system for loading material onto cars of a train is disclosed. The system comprises a material bin arranged to receive material to be loaded onto the train, a closure device arranged to facilitate control by an operator of the amount of material loaded into each car from the material bin, and a car mass estimator arranged to estimate the mass of material loaded into each car. The system also comprises a display arranged to communicate to the operator the estimated mass of material loaded into each car. A corresponding method is also disclosed.

Abstract: An apparatus for producing metal organic frameworks, comprising: a tubular flow reactor comprising a tubular body into which, in use, precursor compounds which form the metal organic framework are fed and flow, said tubular body including at least one annular loop.

Abstract: The invention relates to drug development and synthetic chemistry, in particular to the manufacture of biologically active compounds based on naturally occurring molecules. It also relates to novel biologically active compounds, for example aminoglycoside antibiotics, in a substantially pure regioisomeric form. More particularly, the present invention relates to methods for the chemo- or regioselective derivatization of a target compound with multiple reactive groups, some of which may be derivatezed, and other which will not be derivatized.

Abstract: The invention relates to the field of carbohydrate chemistry. Provided is a process for the regioselective oxidation of a single secondary hydroxy function of a carbohydrate substrate comprising two or more secondary hydroxy functions, comprising contacting the carbohydrate substrate in a solvent in the presence of a transition metal catalyst complex with an oxidizing agent to yield a mono-oxidized carbohydrate.

Abstract: An apparatus for producing metal organic frameworks, comprising: a tubular flow reactor comprising a tubular body into which, in use, precursor compounds which form the metal organic framework are fed and flow, said tubular body including at least one annular loop.

Abstract: An apparatus for producing metal organic frameworks, comprising: a tubular flow reactor comprising a tubular body into which, in use, precursor compounds which form the metal organic framework are fed and flow, said tubular body including at least one annular loop.

Abstract: An apparatus for producing metal organic frameworks, comprising: a tubular flow reactor comprising a tubular body into which, in use, precursor compounds which form the metal organic framework are fed and flow, said tubular body including at least one annular loop.

Abstract: An apparatus for producing metal organic frameworks, comprising: a tubular flow reactor comprising a tubular body into which, in use, precursor compounds which form the metal organic framework are fed and flow, said tubular body including at least one annular loop.

Abstract: A train loading system for loading material onto cars of a train is disclosed. The system comprises a material bin arranged to receive material to be loaded onto the train, a closure device arranged to facilitate control by an operator of the amount of material loaded into each car from the material bin, and a car mass estimator arranged to estimate the mass of material loaded into each car. The system also comprises a display arranged to communicate to the operator the estimated mass of material loaded into each car. A corresponding method is also disclosed.

Abstract: This invention comprises filled silicone compositions initially having a slump of at least 2.5 millimeters when tested described in ASTM D2202-00(2010) except temperature shall be 25 degrees Celsius and time shall be 5 minutes, and a method of preparing and uses of the composition.

Abstract: The invention relates to the field of carbohydrate chemistry. Provided is a process for the regioselective oxidation of a single secondary hydroxy function of a carbohydrate substrate comprising two or more secondary hydroxy functions, comprising contacting the carbohydrate substrate in a solvent in the presence of a transition metal catalyst complex with an oxidizing agent to yield a mono-oxidized carbohydrate.