Abstract: A transgenic non-human animal for overexpressing isoQC, comprising cells containing a DNA transgene encoding human isoQC, characterized in that said human isoQC comprises the amino acid sequence of SEQ ID NO: 1 or an amino acid sequence having at least 75% sequence identity to the amino acid sequence of SEQ ID NO: 1 or a fragment or derivative of the amino acid sequence of SEQ ID NO: 1. Additionally disclosed is a method of screening for biologically active agents that inhibit or promote isoQC.

Abstract: The present invention relates to a joining component for axial joining to a workpiece, having a base body composed of thermoplastic material which has a holding section and a flange section, with a joining surface being formed on the flange section and having a metal section which can be heated inductively. The metal section is in this case integrated in the flange section.

Abstract: The invention relates to a method for axial joining of a hybrid joining component to a workpiece, wherein the joining component has a thermoplastic joining section and a metal section which can be heated, having the following steps: moving the joining component into contact with a surface of the workpiece; heating of the metal section such that the joining section at least partially melts; ending the heating of the metal section such that the joining component makes a force-fitting, interlocking and/or integral connection with the surface of the workpiece. In this case, the joining component is held with a regulated force and/or in a regulated position with respect to the workpiece at least during the heating of the metal section, in such a manner that the joining component can be joined to the surface of the workpiece without any opposing support.

Abstract: Aluminum parts, such as heat exchangers, with improved resistance towards corrosion caused by contact with stationary water or aqueous compositions can be obtained by addition of Li compounds to the flux used for brazing such parts. LiF and especially Li fluoroaluminates are very suitable. Another aspect of the invention concerns fluxes containing Li salts and their use for brazing of aluminum parts.

Abstract: A wheel bearing unit having which has an outer ring, one or two inner rings and load-transmitting rolling elements arranged between the two rings. An orbitally formed shoulder of a wheel hub is provided for the pre-stressing of the wheel bearing unit via the inner ring, and a toothed ring which has an outward-facing radial tooth system is arranged on the inner ring, as is usual in wheel bearing units with all-wheel drive capability. The wheel bearing unit has a small axial width which benefits the handling characteristics of a vehicle by attaching the toothed ring to the orbitally formed shoulder and transmitting the drive torques via this attachment. Welding and a plastically formed tooth system on the orbitally formed shoulder are proposed as examples of such fastening.

Abstract: The invention relates to an automatic system for maneuvering aircraft on the ground, based on driverless towing vehicles, (hereafter AGTV's), which can independently hold the undercarriage of the aircraft. In said system the AGTVs pull the aircraft from transfer areas on the taxiways of the runways to the stand and vice versa, allowing the propulsion systems of the aircraft to remain switched off during the taxiing process. The driverless AGTVs receive their driving jobs from a computer-aided guidance and management system which controls the AGTV fleet in a collision- and conflict-free manner.

Abstract: A method for producing a tubular drive shaft is described, comprising a first section with a first diameter and a second section with a second diameter, said second diameter being smaller than the first diameter, and a transition section in which a diameter of said drive shaft diminishes from the first diameter to the second diameter and which is provided with an annular bead which coaxially surrounds a longitudinal axis of said drive shaft, and in the process of which method, a tube with the first diameter is reshaped and reduced in diameter to form the second section and the transition section. According to the invention it is provided that the bead is formed during, after, or during a break in the reshaped process that results in the production of a second section with a second diameter.

Abstract: Fluidizable potassium fluorozincate which is very suitable for dry fluxing applications can be prepared from a diluted potassium base selected from the group consisting of KOH, KHCO3 and K2CO3, ZnO and HF. The cumulative volume of the particles has an X10 value of equal to or greater than 1.5 microns, preferably, equal to or greater than 2 microns. It is very suitable for pneumatic transport for aluminum brazing.

Abstract: The present invention relates to the use of laser-engraved printing forms for printing using printing inks in a gravure printing process, where the printing inks are pigmented with flake-form effect pigments, to a corresponding gravure printing process, and to a printing ink.

Abstract: An air supply device (10) for supplying conditioned air into an aircraft passenger cabin comprises an air duct (12) with an air inlet (18), which is connectable to a line system of an aircraft air conditioning system in order to supply conditioned air provided by the aircraft air conditioning system to the air duct (12), and with an air outlet (20), which is connectable to an interior of the aircraft passenger cabin in order to convey the conditioned air supplied to the air duct (12) by the aircraft air conditioning system into the interior of the aircraft passenger cabin. In at least a first portion (14) of the air duct (12) a first boundary wall (24) of the air duct (12) is formed by a portion of a luggage compartment housing back wall (26).

Abstract: Device for rotatably bearing an aircraft interior fitting component A device (10) for rotatably bearing an aircraft interior fitting component, in particular a lowerable shell of a luggage rack, comprises a bearing bush (12) as well as a bearing bolt (32) which is adapted to be rotatably accommodated in the bearing bush to (12). The bearing bolt (32) is disposed in a bearing bolt guide (22) such that it is movable between a first and a second position and retainable in at least one position in the bearing bolt guide (22) by means of a retaining device.

Abstract: The invention relates to a fastening device for an aircraft interior equipment component, with at least one suspension point (12, 14, 16, 18, 20) which is formed to transmit forces to a holding structure in at least one direction. In order to install the aircraft interior equipment components quickly and without tools, the or each suspension point (12, 14, 16, 18, 20) is formed by a rotatable sliding block and a groove, wherein the groove has a transverse dimension as well as a first open end and a second end which leads into a circular recess. The sliding block also has a transverse dimension which is smaller than or equal to the transverse dimension of the groove and a longitudinal dimension which is greater than the transverse dimension of the groove, so that the sliding block can be positively locked by a rotation thereof in the circular recess.

Abstract: An advanced process control (APC) architecture comprising a process model that incorporates a target offset term is provided. The APC architecture may be applied to a so-called develop inspect critical dimension (DICD) model using the target offset term to correct at least one exposure parameter on the occurrence of an abrupt event. A corresponding event may, for example, concern a modified reflectivity of processed substrates, for example due to a rework of substrates covered by amorphous carbon material.

Abstract: A multi-layer film bag with fusible inner layer has gussets fused to front and rear bag walls. Upper end areas of the gussets are folded over toward one bag wall at a folding line to form folded-over end areas. The folding line is oriented at a slant inwardly and downwardly. The inner side of the folded-over end areas is fused by a first welding seam to an inner side of a neighboring gusset half. The outer side of the folded-over end areas is fused by a second welding seam to a neighboring bag wall. An area of the neighboring gusset half adjoining the folded-over end areas is fused by a third welding seam to a neighboring bag wall. The first, second, and third welding seams form a fused connection closing off the top edges of the folded-over end areas.

Abstract: An electronic system with integrated circuit device and passive component is disclosed. One embodiment provides a printed circuit board, a method for fabricating an electronic system, and an electronic system, including at least one integrated circuit device and at least one passive component, wherein the passive component is arranged at least partially underneath the integrated circuit device.

Abstract: The invention relates to noncorrosive auxiliaries for soldering aluminium and for upgrading aluminium alloys based on alkali metal fluoroaluminates, their preparation and their use. According to the invention, the noncorrosive auxiliaries contain metallates. To form the metallates, metal compounds of the elements of main groups 2 to 5 of the PTE or of the transition elements in the form of their salts or oxides are used as reactants. In particular, their halides, nitrates, carbonates, sulphates, phosphates, borates, hexafluorosilicates or oxides, for example, are used. According to the invention, the metal compounds are introduced into the reaction mixture of hydrofluoric acid and/or hydrated alumina and/or alkali metal compound, with the point in time when the metal compound is added being able to be varied as a function of the desired degree of functionalization of the surface.

Abstract: Embodiments include a method and system for digital intraoral x-ray of non-human animals using a flexible and reusable cassette and imaging plate. The imaging plate is activated using an x-ray generator and scanned to capture an image from the imaging plate.

Abstract: The invention provides novel oral modified release dosage forms of neramexane which are useful for the continuous therapy of patients suffering from diseases and conditions such as Alzheimer's dementia and neuropathic pain. The compositions have drug release profiles that are suitable for achieving steady state plasma concentrations of neramexane which have relatively small fluctuation when administered on a twice-daily or even once-daily regimen. The dosage forms may be designed as modified release matrix tablets, which are optionally coated for taste masking. The invention further provides therapeutic methods of treating conditions such as Alzheimer's dementia and neuropathic pain which involve the administration of such dosage forms.

Abstract: The description herein includes cyanine dyes and analogs of the vaso-active intestinal peptide. These are useful to provide peptide-dye conjugates for use as contrast media in optical diagnoses.

Abstract: The present invention relates to the use of laser-engraved printing forms for printing using printing inks in a gravure printing process, where the printing inks are pigmented with flake-form effect pigments, to a corresponding gravure printing process, and to a printing ink.