Patents by Inventor Andreas Beste

Andreas Beste has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20170260264
    Abstract: The present invention provides anti-nerve growth factor (NGF) antibodies that contain an IgG4 constant region comprising a stabilizing hinge region mutation and wherein the antibodies exhibit an unexpectedly long serum half-life in cynomolgus monkeys. Pharmaceutical compositions comprising the anti-NGF antibodies, nucleic acids encoding the NGF antibodies, host cells for expressing the NGF antibodies and methods of using the antibodies for treating NGF-related diseases or conditions are also provided.
    Type: Application
    Filed: September 20, 2016
    Publication date: September 14, 2017
    Inventors: John Powell, Duncan Casson, Mark Maginn, Wei Liu, Sandeep Dutta, Andrea Best, Jerry A. Hall
  • Patent number: 9447181
    Abstract: The present invention provides anti-nerve growth factor (NGF) antibodies that contain an IgG4 constant region comprising a stabilizing hinge region mutation and wherein the antibodies exhibit an unexpectedly long serum half life in cynomolgus monkeys. Pharmaceutical compositions comprising the anti-NGF antibodies, nucleic acids encoding the NGF antibodies, host cells for expressing the NGF antibodies and methods of using the antibodies for treating NGF-related diseases or conditions are also provided.
    Type: Grant
    Filed: May 2, 2013
    Date of Patent: September 20, 2016
    Inventors: John Powell, Duncan Casson, Mark Maginn, Wei Liu, Sandeep Dutta, Andrea Best, Jerry A. Hall
  • Patent number: 8435523
    Abstract: The present invention provides anti-nerve growth factor (NGF) antibodies that contain an IgG4 constant region comprising a stabilizing hinge region mutation and wherein the antibodies exhibit an unexpectedly long serum half life in cynomolgus monkeys. Pharmaceutical compositions comprising the anti-NGF antibodies, nucleic acids encoding the NGF antibodies, host cells for expressing the NGF antibodies and methods of using the antibodies for treating NGF-related diseases or conditions are also provided.
    Type: Grant
    Filed: May 4, 2010
    Date of Patent: May 7, 2013
    Assignee: Abbott Research B.V.
    Inventors: John Powell, Duncan Casson, Mark Maginn, Wei Liu, Sandeep Dutta, Andrea Best, Jerry A. Hall
  • Publication number: 20100278839
    Abstract: The present invention provides anti-nerve growth factor (NGF) antibodies that contain an IgG4 constant region comprising a stabilizing hinge region mutation and wherein the antibodies exhibit an unexpectedly long serum half life in cynomolgus monkeys. Pharmaceutical compositions comprising the anti-NGF antibodies, nucleic acids encoding the NGF antibodies, host cells for expressing the NGF antibodies and methods of using the antibodies for treating NGF-related diseases or conditions are also provided.
    Type: Application
    Filed: May 4, 2010
    Publication date: November 4, 2010
    Applicant: PANGENETICS 110 BV
    Inventors: John Powell, Duncan Casson, Mark Maginn, Wei Liu, Sandeep Dutta, Andrea Best, Jerry A. Hall
  • Patent number: 5956988
    Abstract: The present invention is a novel device and method of shaping an end of a pipe. One end of a pipe is inserted into a shaped die in such a way that the outer surface of the pipe rests against the interior portion of the die. A piston is then inserted into the pipe in such a way that the outer surface of the piston rests against the interior surface of the pipe. The piston is then forcibly driven into the die against the pipe as to forcibly shape the pipe to a predetermined configuration. The present invention also discloses numerous embodiments to shape a pipe.
    Type: Grant
    Filed: June 17, 1997
    Date of Patent: September 28, 1999
    Assignee: Audi AG and Fahrzeugwerk Werdau
    Inventors: Andreas Beste, Hansjorg Lipowsky, Jurgen Oswald, Manfred Janssen
  • Patent number: 5827956
    Abstract: A measuring wheel detects forces and moments between the rim and axle of a vehicle wheel with measuring sensors between the rim face and a wheel flange apparatus transmits the energy and data to a measurement evaluation and processing system on the vehicle. The wheel flange and/or the front of the rim consists of a fiber compound, while the apparatus on the wheel for transmitting energy and data are fitted on the inside of the rim bed holding the vehicle tire and extends essentially over its circumference. Thus the static properties and dynamic behavior of the measuring wheel during travel correspond to the greatest degree to the original wheel. Effects which falsify the measurements such as increased wheel weight and the like do not arise.
    Type: Grant
    Filed: October 10, 1995
    Date of Patent: October 27, 1998
    Assignee: Audi AG
    Inventors: Andreas Beste, Josef Vogler, Frank Hailer, Manfred Muller, Werner Aicher