Abstract: The compressor includes two compression spaces (1, 5) separate from one another, one of which serves to generate the continuous pressure medium flow for the generation of a basic aerosol flow, whereas the other is used to generate the pressure variations. The shared compression device (4), for example a piston, is moved in a pendulum motion by a drive (7) so that a gas is conveyed through the first compression space and pressure variations are imposed upon a gas volume via the second compression space. The drive is disposed in a compression space, use advantageously being made of the space volume available that may if necessary be made use of by the compressor. In a preferred embodiment the drive (7) is located in the compression space (5) that is used to generate the pressure variations.

Abstract: A pharmaceutical aerosol is disclosed which is suitable for delivering an active compound to the mucosa of the nose, the osteomeatal complex or a paranasal sinus. The pressure of the aerosol is not constant, but pulsates at a frequency from about 10 to 90 Hz. The aerosol is further characterised in that it exhibits a low effective flow rate of less than about 5 litres per minute. The aerosol is, inter alia, suitable for the prevention, management, or treatment of a disease, symptom, or condition affecting the nose or the paranasal sinuses, such as acute and chronic sinusitis.

Abstract: A pharmaceutical aerosol is disclosed which is suitable for delivering an active compound to the mucosa of the nose, the osteomeatal complex or a paranasal sinus. The pressure of the aerosol is not constant, but pulsates at a frequency from about 10 to 90 Hz. The aerosol is further characterized in that it exhibits a low effective flow rate of less than about 5 liters per minute. The aerosol is, inter alia, suitable for the prevention, management, or treatment of a disease, symptom, or condition affecting the nose or the paranasal sinuses, such as acute and chronic sinusitis.

Abstract: A roller frame including at least two rollers mounted in a housing between which a nip can be formed. The ends of the rollers are supported in rotary fashion in bearings and at least one of the rollers is embodied as an advancing roller and has an adjusting system by which it is possible to move die bearings of the advancing roller, thus changing the nip. The adjusting system has a rack and a pinion whose teeth engage with those of the rack and can be driven to rotate by a motor. It is possible to change the distance between the pinion and the rack by changing the tooth engagement depth between them.

Abstract: To increase the efficacy of atomizer nozzles operating with compressed gas, an atomizer device for inhalation therapy appliances includes means for delivering a compressed gas, in particular compressed air; means for supplying a fluid that is to be atomized, in particular a therapeutic liquid; several compressed gas outlet openings from which a delivered compressed gas emerges; and several fluid outlet openings from which the fluid to be atomized emerges on account of the emerging compressed gas. The atomizer device includes at least three compressed gas outlet openings arranged in a row, and one of the compressed gas outlet openings is in each case assigned at least two fluid outlet openings which, together with the associated compressed gas outlet opening, form an atomizer nozzle.

Abstract: To increase the efficacy of atomizer nozzles operating with compressed gas, an atomizer device for inhalation therapy appliances includes means for delivering a compressed gas, in particular compressed air; means for supplying a fluid that is to be atomized, in particular a therapeutic liquid; several compressed gas outlet openings from which a delivered compressed gas emerges; and several fluid outlet openings from which the fluid to be atomized emerges on account of the emerging compressed gas. The atomizer device includes at least three compressed gas outlet openings arranged in a row, and one of the compressed gas outlet openings is in each case assigned at least two fluid outlet openings which, together with the associated compressed gas outlet opening, form an atomizer nozzle.

Abstract: The invention relates to a method for producing a purified solution containing L-cysteine from a fermentation broth containing L-cysteine. In said method, the fermentation broth containing L-cysteine, at a pH value from pH 6 to 9, is brought in contact with a basic anion exchanger, wherein the L-cysteine bonds to the anion exchanger. The anion exchanger is then rinsed with a first washing solution, and the bonded L-cysteine is removed from the anion exchanger by means of an acid and transferred into an eluate. Said eluate, having a pH?4, is brought in contact with an acidic cation exchanger, wherein the L-cysteine bonds to the cation exchanger. The cation exchanger is rinsed with a second washing solution, and the bonded L-cysteine is removed from the cation exchanger by means of a strong acid.

Abstract: This disclosure is directed, inter alia, a method of making a dispensing device for dispensing a substance comprising a step of providing a mold having a mold space for receiving a solidifyable material. The method further comprises steps of providing a valve member having a first portion formed between first and second areas of an outer surface of the valve member; placing the valve member into the mold space such that at the first area is isolated from the mold space and at least part of the second area is within the mold space; displacing the first portion at least partially relative to another portion of the valve member; and solidifying the material in the mold space and thereby fixing the displaced first portion in place. In one embodiment, the method helps minimizing manufacturing costs and maximizing shelf life of a device filled with substance.

Abstract: A tool closing system for plastic blow molding machines comprises a drive base plate, a front mold clamping plate and a rear mold clamping plate positioned between the front clamping plate and the base plate. The base plate, front clamping plate, and rear clamping plate are shiftably arranged on guides which are mounted on a carriage. A drive device is fastened to the base plate and comprises an extensible and retractable drive rod which is articulated to the rear clamping plate for force transmission without bending moment. Two substantially C-shaped or U-shaped frame elements are arranged side by side in parallel with the guides. Each have a substantially horizontally extending central web and two substantially vertically extending webs. A respective one of the two vertical webs is articulated to the base plate and the other vertical web is articulated to the front clamping plate.

Abstract: A tool closing system for plastic blow molding machines comprises a drive base plate, a front mold clamping plate and a rear mold clamping plate positioned between the front clamping plate and the base plate. The base plate, front clamping plate, and rear clamping plate are shiftably arranged on guides which are mounted on a carriage. A drive device is fastened to the base plate and comprises an extensible and retractable drive rod which is articulated to the rear clamping plate for force transmission without bending moment. Two substantially C-shaped or U-shaped frame elements are arranged side by side in parallel with the guides. Each have a substantially horizontally extending central web and two substantially vertically extending webs. A respective one of the two vertical webs is articulated to the base plate and the other vertical web is articulated to the front clamping plate.

Abstract: A device for producing blown films, including an extrusion device generating a tubular film and a flattening device, associated with the tubular film, having two flattening elements, arranged on diametrically opposite zones of the tubular film and adjustable in relation to each other at an acute angle, for transforming a cross-section of the tubular film, which is first circular, then oval, to a double-layer film web. This invention has lateral guide elements for the areas of the tubular film that are not affected by the flattening elements and are arranged between the flattening elements and are associated with the tubular film and the lateral guide elements have an adjustable contour.

Abstract: An element is provided for a cable carrier device which is constructed and arranged to carry cabling components such as cables, lines, hoses and the like between a first connection point and a second connection point. The element is formed from a material including at least one plastic and a filler. The filler includes three-dimensional geometrical carbon-based structures having nanometer-scale dimensions. In some arrangements, the carbon-based structures are carbon nanotubes formed of carbon atoms. Accordingly, the element is capable of dissipating electrostatic charges of the cable carrier device. Thus, the corresponding cable carrier device is suitable for working environments that are to be protected from electrostatic effects.

Abstract: A breath-controlled inhalation therapy device includes an obturation mechanism, obturating a nozzle opening through which a pressurised gas, preferably pressurised air, is issued when the device is in operation. An actuation mechanism actuates the obturation mechanism only in the exhalation phases of the respiration cycle of a patient. The fluid to be atomised is therefore substantially atomised only in the inhalation phases.

Abstract: A breath-controlled inhalation therapy device includes an obturation mechanism, obturating a nozzle opening through which a pressurised gas, preferably pressurised air, is issued when the device is in operation. An actuation mechanism actuates the obturation mechanism only in the exhalation phases of the respiration cycle of a patient. The fluid to be atomised is therefore substantially atomised only in the inhalation phases.

Abstract: In a first aspect, the invention relates to a method for operating an aerosol inhalation device (10), comprising the steps of transporting a certain amount of an aerosol to a desired location outside said device (10) and vibrating the transported aerosol when it has reached said desired location. In a second aspect, the invention relates to an aerosol inhalation device (10) comprising a pump (1) for flowing a certain amount of an aerosol to a desired location outside the device (10), a vibrator (2) for vibrating the transported aerosol in a vibration mode and a control configured to actuate the vibrator (2) for vibrating the flowed aerosol only when it has reached said desired location.

Abstract: A breath-controlled inhalation therapy device includes an obturation mechanism, obturating a nozzle opening through which a pressurized gas, preferably pressurized air, is issued when the device is in operation. An actuation mechanism actuates the obturation mechanism only in the exhalation phases of the respiration cycle of a patient. The fluid to be atomized is therefore substantially atomized only in the inhalation phases.