Abstract: The present invention relates to a new method for determining the allele frequency and/or mutation rate in nucleic acids, in particular in tumor nucleic acids, in the context of a polymerase chain reaction (PCR), and to diagnostics for this purpose, wherein at least one reference nucleic acid (RN) and one mutation sequence with respect to the reference nucleic acid are used. This reference nucleic acid and mutation sequence allows polymerase chain reaction (PCR) methods to be validated, in particular on the basis of device parameters and sample preparation. Furthermore, the invention relates to an associated diagnosis and prognosis method, in particular for tumor diagnosis as part of a liquid biopsy.

Abstract: In a method for the training of a listening situation classifier for a hearing aid, a user is presented with a number of acoustic signals by use of a terminal device, which prompts the user to indicate the signal source of the signal or the particular presented signal. The training data is adapted for the listening situation classifier in dependence on the user's indication of the presented signal or one of the possibly several signals presented and updates the listening situation classifier by use of the training data.

Abstract: In a method for the training of a listening situation classifier for a hearing aid, a user is presented with a number of acoustic signals by use of a terminal device, which prompts the user to indicate the signal source of the signal or the particular presented signal. The training data is adapted for the listening situation classifier in dependence on the user's indication of the presented signal or one of the possibly several signals presented and updates the listening situation classifier by use of the training data.

Abstract: The invention relates to a device for detecting analytes. In order to supply a need in alternative prenatal diagnostic methods which do not include the risks known in the state of art, the present invention provides a device for detecting analytes, including a polymer fiber and capturing molecules, wherein the capturing molecules bind to an analyte and/or a linker molecule.

Abstract: The invention relates to a detection device for the in vivo and/or in vitro enrichment of sample material, comprising a functional surface charged with detection receptors. To ensure the diagnosis of different diseases using a detection device of the type mentioned at the outset with less efforts and an improved precision of the diagnosis, it is provided according to the invention that the detection device comprises at least one guide element and at least two functional elements disposed at the guide element, wherein a functional surface charged with detection receptors is formed at each of them, the functional elements being designed for being detachable from each other and/or individually detachable from the guide element. Furthermore, the invention provides a use of and a method for the application of said detection device.

Abstract: The present invention refers to a detection device for the in vivo and/or in vitro enrichment of sample material, the detection device comprising a functional surface equipped with detection receptors. To further improve the enrichment of sample material by using a detection device of the aforementioned type, it is provided according to the invention that the functional surface has a three-dimensional structure with mutually facing functional sections which form spaces that can be filled with a sample liquid. Furthermore, the present invention provides for a use and for a method for the use of the detection device.

Abstract: The present invention relates to a method for improving the biocompatibility of a surface, in particular a solid body surface, as well as a device, for example an implant, sensor or cell culture vessel, which is brought in contact with biological systems with a biocompatible surface. To improve the biocompatibility of surfaces, in particular in relation to cell cultures and tissues, in a simple way and for a plurality of different surfaces, the surface is meant to be brought in contact with reactive radicals according to the invention. The device according to the invention has a biocompatible surface that has been treated pursuant to the method according to the invention.

Abstract: A rapid test is provided for detecting pathogenic material, particularly for supporting the diagnosis of sepsis, as well as a kit and a device for the implementation of a sepsis test.

Abstract: The present invention relates to a catheter (1). To provide a device permitting the real-time tracing and detection of sample material (2), the catheter (1) according to the invention comprises at least one detection device (4, 4a) for supplying real-time detection of the sample material (2), wherein the at least one detection device (4, 4a) has a functionalized surface (5, 5a) for accumulating the sample material (2), a signal converter (6), which converts the accumulation of sample material (2) on the functionalized surface (5, 5a) into a binding signal (7), and a signal line (8) for transmitting the binding signal (7).

Abstract: The invention relates to a detection device for the in vivo and/or in vitro enrichment of sample material, comprising a functional surface charged with detection receptors. To ensure the diagnosis of different diseases using a detection device of the type mentioned at the outset with less efforts and an improved precision of the diagnosis, it is provided according to the invention that the detection device comprises at least one guide element and at least two functional elements disposed at the guide element, wherein a functional surface charged with detection receptors is formed at each of them, the functional elements being designed for being detachable from each other and/or individually detachable from the guide element. Furthermore, the invention provides a use of and a method for the application of said detection device.

Abstract: The present invention refers to a detection device for the in vivo and/or in vitro enrichment of sample material, the detection device comprising a functional surface equipped with detection receptors. To further improve the enrichment of sample material by using a detection device of the aforementioned type, it is provided according to the invention that the functional surface has a three-dimensional structure with mutually facing functional sections which form spaces that can be filled with a sample liquid. Furthermore, the present invention provides for a use and for a method for the use of the detection device.

Abstract: The invention relates to a device for detecting analytes. In order to supply a need in alternative prenatal diagnostic methods which do not include the risks known in the state of art, the present invention provides a device for detecting analytes, including a polymer fiber and capturing molecules, wherein the capturing molecules bind to an analyte and/or a linker molecule.

Abstract: The invention relates to a laundry treatment machine, more especially a washing machine or a laundry dryer, comprising a drivable drum which accommodates laundry and is rotatably mounted in a container integral with the housing, wherein the container is provided with an elastic sleeve, covering the transition from the front opening of the container to the housing opening, around the filler opening of the drum, and wherein a laundry rejector is attached in this transitional region in the region of the top dead center of the drum. For improvement purposes, a specially configured laundry rejector is provided in the region of the top dead center of the drum in conjunction with a receiving means in the sleeve in order to avoid laundry items from becoming damaged.

Abstract: The invention concerns a washing machine door for a front-load washing machine that has a frontal frame hinged to the housing of the machine and that surrounds a loading opening, into which a transparent frontal door cover is inserted from the drum side and is held in by a mounted gallows frame. If according to the invention the provision is made that the frontal frame has bayonet hooks on the backside facing the frontal door cover that are inserted into receiving slots of the frontal door cover and held therein when the frontal door cover is rotated; that at least part of the bayonet hooks provide fashioned screw domes onto which receptacle domes of the gallows frame can be form locked; and that the gallows frame with bent rest tabs can be snapped into the rest slots of the frontal door covering.

Abstract: The invention relates to a laundry treatment machine, more especially a washing machine or a laundry dryer, comprising a drivable drum which accommodates laundry and is rotatably mounted in a container integral with the housing, wherein the container is provided with an elastic sleeve, covering the transition from the front opening of the container to the housing opening, around the filler opening of the drum, and wherein a laundry rejector is attached in this transitional region in the region of the top dead center of the drum. For improvement purposes, a specially configured laundry rejector is provided in the region of the top dead center of the drum in conjunction with a receiving means in the sleeve in order to avoid laundry items from becoming damaged.

Abstract: The invention concerns a closing device for a washing machine or clothes dryer with a machine door that locks a loading opening exhibiting a closing piston mounted onto the machine door hinged to the machine housing and a lock in the area of the loading opening, whereby the lock is provided with a latching element that brings the closing piston into a latching closed position when the machine door closes and releases it to an open position when the machine door is opened. An automatic adjustment of the closing piston to the latching element when the machine door closes is achieved in that the closing piston can be adjusted horizontally to a limited extent in the door rim, and that the closing piston with its nose is alignable with the latching element in a receiving element in the door frame around the loading opening.

Abstract: The invention concerns a washing machine door for a front-load washing machine that has a frontal frame hinged to the housing of the machine and that surrounds a loading opening, into which a transparent frontal door cover is inserted from the drum side and is held in by means of a mounted gallows frame. If according to the invention the provision is made that the frontal frame has bayonet hooks on the backside facing the frontal door cover that are inserted into receiving slots of the frontal door cover and held therein when the frontal door cover is rotated; that at least part of the bayonet hooks provide fashioned screw domes onto which receptacle domes of the gallows frame can be form locked; and that the gallows frame with bent rest tabs can be snapped into the rest slots of the frontal door covering, then a washing machine door-module for various washing machine doors is achieved with simple components without great expense for parts or assembly.

Abstract: The invention concerns a closing device for a washing machine or clothes dryer with a machine door that locks a loading opening exhibiting a closing piston mounted onto the machine door hinged to the machine housing and a lock in the area of the loading opening, whereby the lock is provided with a latching element that brings the closing piston into a latching closed position when the machine door closes and releases it to an open position when the machine door is opened. An automatic adjustment of the closing piston to the latching element when the machine door closes is achieved in that the closing piston can be adjusted horizontally to a limited extent in the door rim, and that the closing piston with its nose is alignable with the latching element in a receiving element in the door frame around the loading opening.

Abstract: The present invention refers to a method for producing vasodilation or analgesia in a mammal, comprising the use of vegetal material derived from the bark of a Trichilia species.

Abstract: The method includes deriving all receiver carrier frequencies and all transmitter carrier frequencies of the base station from a common reference frequency; comparing a transmitter carrier frequency of a subscriber station with a receiver carrier frequency in the base station to obtain an average frequency deviation; transmitting the average frequency deviation to the concerned subscriber station; adjusting the transmitter carrier frequency of the subscriber station so that the frequency deviation is minimized; when data is to be transmitted with other carrier frequencies, switching from the receiver channel and transmitter channel to other channels; and prior to switching deriving new transmitter and receiver carrier frequencies (TMTx2, TMRx2) of the subscriber station according to the following formulae: TMTx2={1/C}[BSRx2+ZFLOBS(m′−n·C)+RFLOBS(1−R)], TMRx2={1/C}[BSTx2+ZFLOBS(m−n′·C)+RFLOBS(1&mi