Patents by Inventor Andreas Bomhard

Andreas Bomhard has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5811560
    Abstract: The invention pertains to a method for preparing 8-alpha,12-oxido-13,14,15,16, -tetranorlabdane by cyclizing a mixture of hydroxy-olefins (I)-(III. See the specification for their formulae. The cyclization is carried out in the presence of 10 to 100 wt. % acid, relative to the mixture of compounds (I) to (III).
    Type: Grant
    Filed: May 5, 1997
    Date of Patent: September 22, 1998
    Assignee: Henkel Kommanditgesellschaft auf Aktien
    Inventors: Georg Knuebel, Andreas Bomhard, Thomas Markert
  • Patent number: 5688976
    Abstract: The invention relates to a process for producing 8.alpha.,12-oxido-13,14,15,16-tetranorlabdane through the cyclizing dehydration of 8.alpha.,12 -dihydroxy-13,14,15,16-tetranorlabdane in the presence of aluminophyllosilicates.
    Type: Grant
    Filed: July 3, 1996
    Date of Patent: November 18, 1997
    Assignee: Henkel Kommanditgesellschaft auf Aktien
    Inventors: Georg Knuebel, Andreas Bomhard, Ulf-Armin Schaper, Theo Stalberg, Thomas Markert
  • Patent number: 5670670
    Abstract: In a process for the production of 8.alpha.,12-oxido-13,14,15,16-tetranorlabdane by dehydration of 8.alpha.,12-dihydroxy-13,14,15,16-tetranorlabdane (diol), wherein the diol is subjected to cyclizing dehydration in the presence of 5 to 80% by weight, based on the diol, of at least one alumino layer silicate selected from K catalysts which have an acid charge of less than 100 mval/100 g.
    Type: Grant
    Filed: May 31, 1996
    Date of Patent: September 23, 1997
    Assignee: Henkel Kommanditgesellschaft auf Aktien
    Inventors: Georg Knuebel, Andreas Bomhard, Ulf-Armin Schaper, Theo Stalberg, Thomas Markert
  • Patent number: 5541229
    Abstract: The invention relates to benzimidazoles of the formula ##STR1## in which R.sub.1 to R.sub.2 are as defined in claim 1,1 and 3 isomer mixtures thereof and addition salts thereof which have valuable properties.In particular, the novel compounds are angiotensin II antagonists.
    Type: Grant
    Filed: April 13, 1994
    Date of Patent: July 30, 1996
    Assignee: Dr. Karl Thomae GmbH
    Inventors: Berthold Narr, Andreas Bomhard, Norbert Hauel, Jacques Van Meel, Wolfgang Wienen, Michael Entzeroth
  • Patent number: 5519138
    Abstract: A phenylalkyl derivative of the formula ##STR1## wherein R.sub.a to R.sub.f, A and B are substituents and n is the number 0 or 1.These phenylalkyl derivatives possess angiotensin antagonist activity.
    Type: Grant
    Filed: December 1, 1994
    Date of Patent: May 21, 1996
    Assignee: Dr. Karl Thomae GmbH
    Inventors: Uwe Ries, Manfred Reiffen, Wolfgang Grell, Norbert Hauel, Berthold Narr, Armin Heckel, Andreas Bomhard, Jacques van Meel, Wolfgang Wienen, Michael Entzeroth
  • Patent number: 5175157
    Abstract: Disclosed are new cyclic amine derivatives of the formula I ##STR1## wherein the substituents are defined in the specification. These compounds are useful as for treating sinus tachycardia.
    Type: Grant
    Filed: July 3, 1991
    Date of Patent: December 29, 1992
    Assignee: Boehringer Ingelheim GmbH
    Inventors: Manfred Psiorz, Joachim Heider, Andreas Bomhard, Manfred Reiffen, Norbert Hauel, Klaus Noll, Berthold Narr, Christian Lillie, Walter Kobinger, Jurgen Dammgen
  • Patent number: 5116986
    Abstract: The present invention relates to new heteroaromatic amine derivatives of general formula ##STR1## wherein the substituents are defined hereinbelow, which have valuable pharmacological properties, particularly a heart rate lowering activity and a positive inotropic activity.
    Type: Grant
    Filed: May 7, 1991
    Date of Patent: May 26, 1992
    Assignee: Dr. Karl Thomae GmbH
    Inventors: Andreas Bomhard, Joachim Heider, Manfred Psiorz, Norbert Hauel, Berthold Narr, Klaus Noll, Christian Lillie, Walter Kobinger, Willi Diederen
  • Patent number: 4912115
    Abstract: The present invention relates to new heteroaromatic amine derivatives of general formula ##STR1## wherein the substituents are defined hereinbelow, which have valuable pharmacological properties, particularly a heart rate lowering activity and a positive inotropic activity.
    Type: Grant
    Filed: November 25, 1987
    Date of Patent: March 27, 1990
    Assignee: Dr. Karl Thomae GmbH
    Inventors: Andreas Bomhard, Joachim Heider, Manfred Psiorz, Norbert Hauel, Berthold Narr, Klaus Noll, Christian Lillie, Walter Kobinger, Willi Diederen
  • Patent number: 4871735
    Abstract: The present invention relates to new naphthyl derivatives of general formula ##STR1## wherein N represents the number 1 or 2,A represents a --CH.sub.2 --, --CO--, --CH.sub.2 CH.sub.2 --, --CH.dbd.CH--, ##STR2## while the atom marked with an x is linked to the phenyl nucleus, E represents a straight chained alkylene group optionally substituted by an alkyl group,G represents a straight chained alkylene group optionally substituted by an alkyl group,L represents a bond or an oxygen atom, if G represents a straight chained alkylene group with 2 to 5 carbon atoms optionally substituted by an alkyl group,R.sub.1 and R.sub.2, which may be identical or different, represent alkyl or alkoxy groups or R.sub.1 and R.sub.2 together represent an alkylenedioxy group,R.sub.3 represents a hydrogen atom, or an alkyl or an allyl group,R.sub.4, R.sub.5 and R.sub.
    Type: Grant
    Filed: September 11, 1987
    Date of Patent: October 3, 1989
    Assignee: Dr. Karl Thomae GmbH
    Inventors: Joachim Heider, Manfred Psiorz, Andreas Bomhard, Norbert Hauel, Berthold Narr, Klaus Noll, Christian Lillie, Walter Kobinger, Jurgen Dammgen
  • Patent number: 4831027
    Abstract: The invention relates to new imidazo-benzoxazinones of formula ##STR1## wherein the substituents are defined herein below, which compounds are useful in the treatment of cardiovascular disorders.
    Type: Grant
    Filed: October 5, 1987
    Date of Patent: May 16, 1989
    Assignee: Dr. Karl Thomae GmbH
    Inventors: Berthold Narr, Norbert Hauel, Klaus Noll, Joachim Heider, Manfred Psiorz, Andreas Bomhard, Jacques van Meel, Willi Diederen
  • Patent number: 4737495
    Abstract: The invention relates to new heteroaromatic amine derivatives of formula ##STR1## wherein A represents a --CH.sub.2 --CH.sub.2 --, --CH.dbd.CH--or ##STR2## group and B represents a methylene, carbonyl or thiocarbonyl group or A represents a --CO--CO or ##STR3## group and B represents a methylene group, in which the carbon atom marked x is linked to the phenyl nucleus,E represents a straight-chained alkylene group optionally substituted by an alkyl group,G represents a straight-chained alkylene group optionally substituted by an alkyl group,R.sub.1 represents a hydrogen, fluorine, chlorine or bromine atom, a trifluoromethyl, nitro, amino, alkylamino, dialkylamino, alkyl, alkylmercapto, hydroxy, alkoxy or phenylalkoxy group,R.sub.2 represents a hydrogen, chlorine or bromine atom or a hydroxy, alkoxy, phenylalkoxy or alkyl group orR.sub.1 and R.sub.2 together represent an alkylenedioxy group,R.sub.
    Type: Grant
    Filed: May 30, 1986
    Date of Patent: April 12, 1988
    Assignee: Dr. Karl Tomae, GmbH
    Inventors: Andreas Bomhard, Manfred Psiorz, Joachim Heider, Norbert Hauel, Klaus Noll, Berthold Narr, Walter Kobinger, Christian Lillie
  • Patent number: 4716169
    Abstract: The invention relates to new imidazo derivatives of the formula ##STR1## wherein "A-D and R.sup.1 -R.sup.3 are as defined in the specification". The new compounds have valuable pharmacological properties, particularly antithrombotic and cardiovascular properties such as a cardiotonic activity and/or an effect on blood pressure, and can be prepared using methods known per se.
    Type: Grant
    Filed: December 17, 1985
    Date of Patent: December 29, 1987
    Assignee: Dr. Karl Thomae GmbH
    Inventors: Joachim Heider, Norbert Hauel, Volkhard Austel, Klaus Noll, Andreas Bomhard, Jacques van Meel, Willi Diederen