Patents by Inventor Andreas Bosic

Andreas Bosic has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD AND KIT FOR CHARACTERIZING DOPAMINERGIC PROGENITOR CELLS OBTAINED BY DIFFERENTIATING PLURIPOTENT STEM CELLS
    Publication number: 20240248076
    Abstract: The present invention provides an in-vitro method for analyzing a cell composition comprising human floorplate mesDA progenitor cells, the method comprising a) contacting the cells of said cell composition or the cells of a sample thereof with antigen binding molecules specific for the antigens FOXA2, OTX2, PAX6, and NKX6.1, thereby labeling the cells of said cell composition or of said sample, b) determining the percentage of said cells that are labelled with said antigen binding molecules for each of said antigens, and wherein the cells of said cell composition qualify as human floorplate mesDA progenitor cells if the protein expression profile of said cells is: 80-100% of said cells are positive for FOXA2, 80-100% of said cells are positive for OTX2, less than 10% of said cells are positive for PAX6, and less than 10% of said cells are positive for NKX6.1. A kit comprising said antigen binding molecules for use in said method is also provided.
    Type: Application
    Filed: February 16, 2024
    Publication date: July 25, 2024
    Applicant: Miltenyi Biotec B.V. & Co. KG
    Inventors: Melanie Jungblut, Andreas Bosic, Sebastian Knobel, Agnete Kirkeby, Malin Parmar