Abstract: A liquid-dispensing pad has a perforated generally elastic film forming a front wall, a liquid-impervious plastic rear wall, a weld peripherally securing the front wall to the rear wall, and a liquid-retaining core between the front and rear walls. The perforated film is a coextruded film having an elastic inner layer turned toward the core and an inelastic outer cover layer turned away from the core. This cover layer forms an outer face of the liquid-dispensing pad and is composed of polyolefin. A thickness of the cover layer is less than 15 ?m, and a thickness ratio of the elastic inner layer to the inelastic outer cover layer is at least 10:1.

Abstract: A liquid-dispensing pad has a perforated generally elastic film forming a front wall, a liquid-impervious plastic rear wall, a weld peripherally securing the front wall to the rear wall, and a liquid-retaining core between the front and rear walls. The perforated film is a coextruded film having an elastic inner layer turned toward the core and an inelastic outer cover layer turned away from the core. This cover layer forms an outer face of the liquid-dispensing pad and is composed of polyolefin. A thickness of the cover layer is less than 15 ?m, and a thickness ratio of the elastic inner layer to the inelastic outer cover layer is at least 10:1.

Abstract: The present invention provides a process for identifying substances that modulate the activity of hyperpolarization-activated cation channels, and the use of this process.

Abstract: The present invention relates to a novel human K+ ion channel, to nucleic acid molecules encoding the same and to vectors comprising said nucleic acid molecules. The invention additionally relates to antibodies specifically directed to the novel K+ ion channel and to pharmaceutical compositions and diagnostic kits containing at least one of the above-mentioned components. Furthermore, the present invention relates to methods of treating a disease caused by malfunction of the polypeptide of the present invention or by the (over)expression of the nucleic acid molecule of the invention comprising administering an inhibitor of said (over)expression or of ion channel function or an inhibitor abolishing said malfunction to a patient in need thereof. Methods of devising drugs for treating or preventing the above-mentioned disease, methods of inhibiting cell proliferation and methods of prognosing cancer are additional embodiments comprised by the present invention.