Patents by Inventor Andreas D. Christ

Andreas D. Christ has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted piperidines as somatostatin receptor subtype 5 (SSTR5) antagonists
    Patent number: 8026255
    Abstract: This invention is concerned with compounds of the formula and pharmaceutically acceptable salts thereof. The invention further relates to pharmaceutical compositions containing such compounds, to a process for their preparation and to their use for the treatment and/or prevention of diseases which are associated with the modulation of SST receptors subtype 5.
    Type: Grant
    Filed: May 10, 2010
    Date of Patent: September 27, 2011
    Assignee: Hoffman-La Roche Inc.
    Inventors: Alfred Binggeli, Andreas D. Christ, Hans P. Maerki, Rainer E. Martin
  • Substituted piperidine derivatives as SST5 modulators
    Patent number: 7968568
    Abstract: This invention is concerned with compounds of the formula wherein A, R1 to R5 and G are as defined in the description and claims, and pharmaceutically acceptable salts thereof. The invention further relates to pharmaceutical compositions containing such compounds, to a process for their preparation and to their use for the treatment and/or prevention of diseases which are associated with the modulation of SST receptors subtype 5.
    Type: Grant
    Filed: November 19, 2009
    Date of Patent: June 28, 2011
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Andreas D. Christ, Rainer E. Martin
  • Pyridine, quinoline and pyrimidine derivatives
    Patent number: 7939661
    Abstract: This invention is concerned with compounds of the formula wherein A, R1 to R5 are as defined in the specification and G is a pyridine, quinoline or pyrimidine group as defined in the specification, and pharmaceutically acceptable salts thereof. The invention further relates to pharmaceutical compositions containing such compounds, to a process for their preparation and to their use for the treatment and/or prevention of diseases which are associated with the modulation of SST receptors subtype 5.
    Type: Grant
    Filed: August 30, 2007
    Date of Patent: May 10, 2011
    Assignee: Hoffman-La Roche Inc.
    Inventors: Andreas D. Christ, Rainer E. Martin, Peter Mohr
  • Substituted n-benzyl piperidines as somatostatin receptor modulators
    Patent number: 7799806
    Abstract: This invention relates to compounds of the formula wherein A, R1 to R3 are as defined in the claims and G is benzoimidazole, quinoxaline, benzotriazole, dihydro-imidazo[4,5-c]pyridinone and dihydro-isoindolone group as defined in the specification, and pharmaceutically acceptable salts thereof. The invention further relates to pharmaceutical compositions containing such compounds, to a process for their preparation and to their use for the treatment and/or prevention of diseases which are associated with the modulation of SST receptors subtype 5 such as diabetes mellitus.
    Type: Grant
    Filed: March 24, 2008
    Date of Patent: September 21, 2010
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Konrad Bleicher, Andreas D. Christ, Rainer E. Martin, Peter Mohr
  • PHENYL, PYRIDINE, QUINOLINE, ISOQUINOLINE, NAPHTHYRIDINE AND PYRAZINE DERIVATIVES
    Publication number: 20100222350
    Abstract: This invention is concerned with compounds of the formula and pharmaceutically acceptable salts thereof. The invention further relates to pharmaceutical compositions containing such compounds, to a process for their preparation and to their use for the treatment and/or prevention of diseases which are associated with the modulation of SST receptors subtype 5.
    Type: Application
    Filed: May 10, 2010
    Publication date: September 2, 2010
    Inventors: Alfred Binggeli, Andreas D. Christ, Hans P. Maerki, Rainer E. Martin
  • Substituted piperidinamines as somatostatin receptor subtype 5 (SSTR5) antagonists
    Patent number: 7754744
    Abstract: This invention is concerned with compounds of the formula and pharmaceutically acceptable salts thereof. The invention further relates to pharmaceutical compositions containing such compounds, to a process for their preparation and to their use for the treatment and/or prevention of diseases which are associated with the modulation of SST receptors subtype 5.
    Type: Grant
    Filed: August 6, 2007
    Date of Patent: July 13, 2010
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Alfred Binggeli, Andreas D. Christ, Hans P. Maerki, Rainer E. Martin
  • Pyrimidine and Quinazoline Derivatives
    Publication number: 20100069413
    Abstract: This invention is concerned with compounds of the formula wherein A, R1 to R5 and G are as defined in the description and claims, and pharmaceutically acceptable salts thereof. The invention further relates to pharmaceutical compositions containing such compounds, to a process for their preparation and to their use for the treatment and/or prevention of diseases which are associated with the modulation of SST receptors subtype 5.
    Type: Application
    Filed: November 19, 2009
    Publication date: March 18, 2010
    Inventors: Andreas D. Christ, Rainer E. Martin
  • Pyrimidine and quinazoline derivatives as SST5 modulators
    Patent number: 7674804
    Abstract: This invention is concerned with compounds of the formula wherein A, R1 to R5 and G are as defined in the description and claims, and pharmaceutically acceptable salts thereof. The invention further relates to pharmaceutical compositions containing such compounds, to a process for their preparation and to their use for the treatment and/or prevention of diseases which are associated with the modulation of SST receptors subtype 5.
    Type: Grant
    Filed: June 21, 2007
    Date of Patent: March 9, 2010
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Andreas D. Christ, Rainer E Martin
  • ARYLOXAZOLE, ARYLOXADIAZOLE AND BENZIMIDAZOLE DERIVATIVES
    Publication number: 20080306116
    Abstract: This invention relates to compounds of the formula wherein X is O or NR8, Y is CR7 or N, and R1 to R8 are as defined in the specification, and pharmaceutically acceptable salts thereof. The invention further relates to pharmaceutical compositions containing such compounds, to a process for their preparation and to their use for the treatment and/or prevention of diseases which are associated with the modulation of SST receptors subtype 5.
    Type: Application
    Filed: May 20, 2008
    Publication date: December 11, 2008
    Inventors: Andreas D. Christ, Rainer E. Martin, Peter Mohr
  • 4,4-DISUBSTITUTED PIPERIDINE DERIVATIVES
    Publication number: 20080293756
    Abstract: This invention relates to 4,4-disubstituted piperidine derivatives of the formula wherein A and R1 to R5 are as defined in the specification, and pharmaceutically acceptable salts thereof. The invention further relates to pharmaceutical compositions containing such compounds, to a process for their preparation and to their use for the treatment and/or prevention of diseases which are associated with the modulation of SST receptors subtype 5.
    Type: Application
    Filed: April 29, 2008
    Publication date: November 27, 2008
    Inventors: Andreas D. Christ, Rainer E. Martin, Peter Mohr
  • BENZOIMIDAZOLE, TETRAHYDRO-QUINOXALINE, BENZOTRIAZOLE, DIHYDRO-IMIDAZO[4,5-c] PYRIDINONE AND DIHYDRO-ISOINDOLONE DERIVATIVES
    Publication number: 20080249101
    Abstract: This invention relates to compounds of the formula wherein A, R1 to R3 are as defined in the specification and G is benzoimidazole, quinoxaline, benzotriazole, dihydro-imidazo[4,5-c]pyridine and dihydro-isoindolone group as defined in the specification, and pharmaceutically acceptable salts thereof. The invention further relates to pharmaceutical compositions containing such compounds, to a process for their preparation and to their use for the treatment and/or prevention of diseases which are associated with the modulation of SST receptors subtype 5.
    Type: Application
    Filed: March 24, 2008
    Publication date: October 9, 2008
    Inventors: Konrad Bleicher, Andreas D. Christ, Rainer E. Martin, Peter Mohr
  • Pyrimidine and quinazoline derivatives
    Publication number: 20080045550
    Abstract: This invention is concerned with compounds of the formula wherein A, R1 to R5 and G are as defined in the description and claims, and pharmaceutically acceptable salts thereof. The invention further relates to pharmaceutical compositions containing such compounds, to a process for their preparation and to their use for the treatment and/or prevention of diseases which are associated with the modulation of SST receptors subtype 5.
    Type: Application
    Filed: June 21, 2007
    Publication date: February 21, 2008
    Inventors: Andreas D. Christ, Rainer E. Martin
  • Phenyl, Pyridine, Quinoline, Isoquinoline, Naphthyridine and Pyrazine Derivatives
    Publication number: 20080045544
    Abstract: This invention is concerned with compounds of the formula and pharmaceutically acceptable salts thereof. The invention further relates to pharmaceutical compositions containing such compounds, to a process for their preparation and to their use for the treatment and/or prevention of diseases which are associated with the modulation of SST receptors subtype 5.
    Type: Application
    Filed: August 6, 2007
    Publication date: February 21, 2008
    Inventors: Alfred Binggeli, Andreas D. Christ, Hans P. Maerki, Rainer E. Martin