Patents by Inventor Andreas Drechsler

Andreas Drechsler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11890623
    Abstract: A bucket insert for use in a centrifuge is disclosed. The bucket insert comprises an insert body, the insert body comprising a plurality of elongated receptacles for receiving elongated sample vessels. The bucket insert is configured for orienting the elongated sample vessels in a tilted orientation. In the tilted orientation, at least some of the elongated sample vessels are oriented in a non-parallel fashion.
    Type: Grant
    Filed: November 20, 2020
    Date of Patent: February 6, 2024
    Assignee: ROCHE DIAGNOSTICS OPERATIONS, INC.
    Inventors: Claudio Cherubini, Andreas Drechsler
  • Patent number: 11759888
    Abstract: According to the present invention, a system (1; 1?) for processing at least one substrate (2) containing a dried fluid sample (21) is provided, the system (1; 1?) comprising a support (12) configured to position the substrate (2), a laser device (3) for directing a laser beam (31) to the substrate (2), configured to cut at least one area of the substrate (2) containing the dried fluid sample (21) by means of the laser beam (31), a container holder (4; 4?) configured to hold and position a container (5) for receiving the cut area, the container holder (4; 4?) being arranged below the substrate (2), and an extraction subsystem (6) for extracting fume and/or dust generated when laser cutting the substrate (2), wherein the extraction subsystem (6) consists of at least two extraction components (61, 62) sandwiching the substrate (2) there between. Furthermore, a method for automated processing at least one substrate (2) containing a dried fluid (21) sample by means of such a system (1; 1?) is provided.
    Type: Grant
    Filed: May 27, 2021
    Date of Patent: September 19, 2023
    Assignee: Roche Molecular Systems, Inc.
    Inventors: Claudio Cherubini, Andreas Drechsler, Reto Huesser, Emad Sarofim
  • Publication number: 20230258680
    Abstract: A system and method for treatment of biological samples is disclosed. In some embodiments, an automated biological sample staining system (100), comprising at least one microfluidic reagent applicator (118); at least one bulk fluid applicator (116); at least one fluid aspirator; at least one sample substrate holder; at least one relative motion system; and a control system (102) that is programmed to execute at least one staining protocol on a sample mounted on a substrate that is held in the at least one sample substrate holder.
    Type: Application
    Filed: April 20, 2023
    Publication date: August 17, 2023
    Inventors: Andreas Drechsler, Oliver Gutmann, Melis Hazar, Reto Huesser, Raymond T. Kozikowski, III, Daniel Mueller, Chris Steinert
  • Patent number: 11668726
    Abstract: A system and method for treatment of biological samples is disclosed. In some embodiments, an automated biological sample staining system (100), comprising at least one microfluidic reagent applicator (118); at least one bulk fluid applicator (116); at least one fluid aspirator; at least one sample substrate holder; at least one relative motion system; and a control system (102) that is programmed to execute at least one staining protocol on a sample mounted on a substrate that is held in the at least one sample substrate holder.
    Type: Grant
    Filed: April 18, 2019
    Date of Patent: June 6, 2023
    Assignees: Ventana Medical Systems, Inc., Roche Diagnostics Operations, Inc.
    Inventors: Andreas Drechsler, Oliver Gutmann, Melis Hazar, Reto Huesser, Raymond T. Kozikowski, III, Daniel Mueller, Chris Steinert
  • Patent number: 11226348
    Abstract: A storage module for a laboratory automation system, a method of operating a laboratory automation system, and a laboratory automation system are presented. Items used by laboratory stations are stored centrally in a storage module and can be transported to the laboratory stations using a laboratory sample distribution system.
    Type: Grant
    Filed: December 15, 2017
    Date of Patent: January 18, 2022
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Urs Vollenweider, Gottlieb Schacher, Goran Savatic, Marco Maetzler, Christoph Ludwig, Christian Loewenstein, Yves Laloux, Rik Harbers, Matthias Edelmann, Andreas Drechsler
  • Patent number: 11204361
    Abstract: A laboratory automation system for processing sample containers containing laboratory samples and/or for processing the samples is presented. The laboratory automation system comprises a digital camera configured to take an image of the sample container together with a calibration element. The image comprises image data related to the sample container and image data related to the calibration element. The laboratory automation system also comprises an image processing device configured to determine geometrical properties of the sample container depending on the image data related to the sample container and the image data related to the calibration element.
    Type: Grant
    Filed: January 19, 2018
    Date of Patent: December 21, 2021
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Armin Birrer, Andreas Drechsler, Rik Harbers
  • Publication number: 20210373042
    Abstract: A module for an automated laboratory system is disclosed. The module comprises a module connector configured to releasably connect to a component of the automated laboratory system, a detector at least configured to detect at least one component marker located at the component so as to obtain position data of the module indicating an actual position of the module, a processor configured to calculate a position deviation of the module from a target position defined by the component based on the position data and to calculate position alignment data based on the position deviation, and a alignment device configured to align the module to the target position based on the position alignment data. Further, an automated laboratory system and a method for aligning a module are disclosed.
    Type: Application
    Filed: May 24, 2021
    Publication date: December 2, 2021
    Applicant: Roche Diagnostics Operations, Inc.
    Inventors: Claudio Cherubini, Andreas Drechsler, Reto Huesser, Ivan Heinzer
  • Patent number: 11130710
    Abstract: A roofing tile composed of concrete material and a method for producing such a roofing tile. The concrete material contains a binder, a gravel, a light-weight aggregate, and added water. The roofing tile has at least one watercourse and a lateral interlocking joint having a covering fold and a water fold. The ratio of water to binder is less than 0.3, the light-weight aggregate is composed of a material that is hydrophobic and/or not hygroscopic, and the roofing tile has a density in the range of 1.6 g/cm3 to 1.9 g/cm3 after the hardening. The roofing tile has a thickness of 5 mm to 9 mm, preferably 7 mm to 8 mm, in the highly loaded regions, preferably in the region of the watercourse.
    Type: Grant
    Filed: February 14, 2018
    Date of Patent: September 28, 2021
    Inventors: Andreas Drechsler, Michael Friedrich, Michael Heise, Jürgen Klein, Stephan Westphal, Ben Cranfield
  • Publication number: 20210283714
    Abstract: According to the present invention, a system (1; 1?) for processing at least one substrate (2) containing a dried fluid sample (21) is provided, the system (1; 1?) comprising a support (12) configured to position the substrate (2), a laser device (3) for directing a laser beam (31) to the substrate (2), configured to cut at least one area of the substrate (2) containing the dried fluid sample (21) by means of the laser beam (31), a container holder (4; 4?) configured to hold and position a container (5) for receiving the cut area, the container holder (4; 4?) being arranged below the substrate (2), and an extraction subsystem (6) for extracting fume and/or dust generated when laser cutting the substrate (2), wherein the extraction subsystem (6) consists of at least two extraction components (61, 62) sandwiching the substrate (2) there between. Furthermore, a method for automated processing at least one substrate (2) containing a dried fluid (21) sample by means of such a system (1; 1?) is provided.
    Type: Application
    Filed: May 27, 2021
    Publication date: September 16, 2021
    Inventors: Claudio Cherubini, Andreas Drechsler, Reto Huesser, Emad Sarofim
  • Patent number: 11112419
    Abstract: A laboratory distribution system is presented. The system comprises diagnostic laboratory container carriers and a conveyor. The conveyor comprises an endless drive defining a closed-loop conveyor pathway. The system comprises supporting elements attached to the endless drive. The supporting elements receive a container carrier and transport the container carrier in an upright position along a pathway section. The supporting elements are mounted pivotally about a horizontal pivot axis to the drive and structured such that a center of gravity of the supporting element with or without an empty or loaded container carrier is arranged below and vertically aligned with the pivot axis when the supporting element is in an upright position such that each supporting element is free to pivot about the associated pivot axis under the effect of gravitational forces acting on the supporting element for maintaining the supporting elements in an upright position while travelling along the path.
    Type: Grant
    Filed: July 10, 2018
    Date of Patent: September 7, 2021
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Hans van Mierlo, Gottlieb Schacher, Marcel Kaeppeli, Reto Huesser, Andreas Drechsler, Matthias Goetz, Nenad Milicevic
  • Patent number: 11067565
    Abstract: A device is described including a lid, a collection portion support, and a collection portion with a surface for receiving a biological sample, the lid includes a window and a window holder, the surface defines a first plane, the collection portion includes a first, a second, and a third position markers, each position marker indicates a center point marker, the center points define a second plane that has a line of intersection with the first plane, the device has an interior volume defined partially by the collection portion support, the collection portion, the window, and the window holder, the window allows visual inspection of the position markers, the collection portion support has a fluid inlet and a fluid outlet with a fluid path from the fluid inlet to the fluid outlet via the interior volume.
    Type: Grant
    Filed: March 16, 2018
    Date of Patent: July 20, 2021
    Assignee: Roche Molecular Systems, Inc.
    Inventors: Andreas Drechsler, Edwin Oosterbroek, Emad Sarofim, Heiko Schwertner
  • Publication number: 20210213450
    Abstract: A method to process a laboratory carrier in a laboratory system based on a feature of a test liquid in the laboratory carrier is presented. The laboratory system comprises the laboratory carrier comprising the test liquid, a terahertz wave source, a terahertz detector, a laboratory carrier processing device, and a control unit. Using terahertz technology and data analysis, the feature of the test liquid in the laboratory carrier can be determined. In addition, the control unit controls the laboratory carrier processing device based on the determined feature of the test liquid.
    Type: Application
    Filed: January 5, 2021
    Publication date: July 15, 2021
    Applicant: Roche Diagnostics Operations, Inc.
    Inventors: Andreas Drechsler, Darko Klinec, Michael Koehler, Alexander Jakob, Michael Zeder
  • Patent number: 11052484
    Abstract: According to the present invention, a system (1; 1?) for processing at least one substrate (2) containing a dried fluid sample (21) is provided, the system (1; 1?) comprising a support (12) configured to position the substrate (2), a laser device (3) for directing a laser beam (31) to the substrate (2), configured to cut at least one area of the substrate (2) containing the dried fluid sample (21) by means of the laser beam (31), a container holder (4; 4?) configured to hold and position a container (5) for receiving the cut area, the container holder (4; 4?) being arranged below the substrate (2), and an extraction subsystem (6) for extracting fume and/or dust generated when laser cutting the substrate (2), wherein the extraction subsystem (6) consists of at least two extraction components (61, 62) sandwiching the substrate (2) there between. Furthermore, a method for automated processing at least one substrate (2) containing a dried fluid (21) sample by means of such a system (1; 1?) is provided.
    Type: Grant
    Filed: May 17, 2018
    Date of Patent: July 6, 2021
    Assignee: Roche Molecular Systems, Inc.
    Inventors: Claudio Cherubini, Andreas Drechsler, Reto Huesser, Emad Sarofim
  • Publication number: 20210154684
    Abstract: A bucket insert for use in a centrifuge is disclosed. The bucket insert comprises an insert body, the insert body comprising a plurality of elongated receptacles for receiving elongated sample vessels. The bucket insert is configured for orienting the elongated sample vessels in a tilted orientation. In the tilted orientation, at least some of the elongated sample vessels are oriented in a non-parallel fashion.
    Type: Application
    Filed: November 20, 2020
    Publication date: May 27, 2021
    Applicant: Roche Diagnostics Operations, Inc.
    Inventors: Claudio Cherubini, Andreas Drechsler
  • Publication number: 20190242921
    Abstract: A system and method for treatment of biological samples is disclosed. In some embodiments, an automated biological sample staining system (100), comprising at least one microfluidic reagent applicator (118); at least one bulk fluid applicator (116); at least one fluid aspirator; at least one sample substrate holder; at least one relative motion system; and a control system (102) that is programmed to execute at least one staining protocol on a sample mounted on a substrate that is held in the at least one sample substrate holder.
    Type: Application
    Filed: April 18, 2019
    Publication date: August 8, 2019
    Inventors: Andreas Drechsler, Oliver Gutmann, Melis Hazar, Reto Huesser, Raymond T. Kozikowski, III, Daniel Mueller, Chris Steinert
  • Patent number: 10329198
    Abstract: A roofing tile composed of concrete material and a method for producing such a roofing tile. The concrete material contains a binder, a gravel, a light-weight aggregate, and added water. The roofing tile has at least one watercourse and a lateral interlocking joint having a covering fold and a water fold. The ratio of water to binder is less than 0.3, the light-weight aggregate is composed of a material that is hydrophobic and/or not hygroscopic, and the roofing tile has a density in the range of 1.6 g/cm3 to 1.9 g/cm3 after the hardening. The roofing tile has a thickness of 5 mm to 9 mm, preferably 7 mm to 8 mm, in the highly loaded regions, preferably in the region of the watercourse.
    Type: Grant
    Filed: February 15, 2016
    Date of Patent: June 25, 2019
    Assignee: Monier Roofing GmbH
    Inventors: Andreas Drechsler, Michael Friedrich, Michael Heise, Jürgen Klein, Stephan Westphal, Ben Cranfield
  • Publication number: 20180333806
    Abstract: According to the present invention, a system (1; 1?) for processing at least one substrate (2) containing a dried fluid sample (21) is provided, the system (1; 1?) comprising a support (12) configured to position the substrate (2), a laser device (3) for directing a laser beam (31) to the substrate (2), configured to cut at least one area of the substrate (2) containing the dried fluid sample (21) by means of the laser beam (31), a container holder (4; 4?) configured to hold and position a container (5) for receiving the cut area, the container holder (4; 4?) being arranged below the substrate (2), and an extraction subsystem (6) for extracting fume and/or dust generated when laser cutting the substrate (2), wherein the extraction subsystem (6) consists of at least two extraction components (61, 62) sandwiching the substrate (2) there between. Furthermore, a method for automated processing at least one substrate (2) containing a dried fluid (21) sample by means of such a system (1; 1?) is provided.
    Type: Application
    Filed: May 17, 2018
    Publication date: November 22, 2018
    Inventors: Claudio Cherubini, Andreas Drechsler, Reto Huesser, Emad Sarofim
  • Publication number: 20180224476
    Abstract: A laboratory automation system for processing sample containers containing laboratory samples and/or for processing the samples is presented. The laboratory automation system comprises a digital camera configured to take an image of the sample container together with a calibration element. The image comprises image data related to the sample container and image data related to the calibration element. The laboratory automation system also comprises an image processing device configured to determine geometrical properties of the sample container depending on the image data related to the sample container and the image data related to the calibration element.
    Type: Application
    Filed: January 19, 2018
    Publication date: August 9, 2018
    Applicant: Roche Diagnostics Operations, Inc.
    Inventors: Armin Birrer, Andreas Drechsler, Rik Harbers
  • Publication number: 20180209964
    Abstract: A device is described including a lid, a collection portion support, and a collection portion with a surface for receiving a biological sample, the lid includes a window and a window holder, the surface defines a first plane, the collection portion includes a first, a second, and a third position markers, each position marker indicates a center point marker, the center points define a second plane that has a line of intersection with the first plane, the device has an interior volume defined partially by the collection portion support, the collection portion, the window, and the window holder, the window allows visual inspection of the position markers, the collection portion support has a fluid inlet and a fluid outlet with a fluid path from the fluid inlet to the fluid outlet via the interior volume.
    Type: Application
    Filed: March 16, 2018
    Publication date: July 26, 2018
    Applicant: Roche Molecular Systems, Inc.
    Inventors: Andreas Drechsler, Edwin Oosterbroek, Emad Sarofim, Heiko Schwertner
  • Publication number: 20180170809
    Abstract: A roofing tile composed of concrete material and a method for producing such a roofing tile. The concrete material contains a binder, a gravel, a light-weight aggregate, and added water. The roofing tile has at least one watercourse and a lateral interlocking joint having a covering fold and a water fold. The ratio of water to binder is less than 0.3, the light-weight aggregate is composed of a material that is hydrophobic and/or not hygroscopic, and the roofing tile has a density in the range of 1.6 g/cm3 to 1.9 g/cm3 after the hardening. The roofing tile has a thickness of 5 mm to 9 mm, preferably 7 mm to 8 mm, in the highly loaded regions, preferably in the region of the watercourse.
    Type: Application
    Filed: February 14, 2018
    Publication date: June 21, 2018
    Inventors: Andreas DRECHSLER, Michael FRIEDRICH, Michael HEISE, Jürgen KLEIN, Stephan WESTPHAL, Ben CRANFIELD