Patents by Inventor Andreas Drechsler
Andreas Drechsler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11890623Abstract: A bucket insert for use in a centrifuge is disclosed. The bucket insert comprises an insert body, the insert body comprising a plurality of elongated receptacles for receiving elongated sample vessels. The bucket insert is configured for orienting the elongated sample vessels in a tilted orientation. In the tilted orientation, at least some of the elongated sample vessels are oriented in a non-parallel fashion.Type: GrantFiled: November 20, 2020Date of Patent: February 6, 2024Assignee: ROCHE DIAGNOSTICS OPERATIONS, INC.Inventors: Claudio Cherubini, Andreas Drechsler
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Patent number: 11759888Abstract: According to the present invention, a system (1; 1?) for processing at least one substrate (2) containing a dried fluid sample (21) is provided, the system (1; 1?) comprising a support (12) configured to position the substrate (2), a laser device (3) for directing a laser beam (31) to the substrate (2), configured to cut at least one area of the substrate (2) containing the dried fluid sample (21) by means of the laser beam (31), a container holder (4; 4?) configured to hold and position a container (5) for receiving the cut area, the container holder (4; 4?) being arranged below the substrate (2), and an extraction subsystem (6) for extracting fume and/or dust generated when laser cutting the substrate (2), wherein the extraction subsystem (6) consists of at least two extraction components (61, 62) sandwiching the substrate (2) there between. Furthermore, a method for automated processing at least one substrate (2) containing a dried fluid (21) sample by means of such a system (1; 1?) is provided.Type: GrantFiled: May 27, 2021Date of Patent: September 19, 2023Assignee: Roche Molecular Systems, Inc.Inventors: Claudio Cherubini, Andreas Drechsler, Reto Huesser, Emad Sarofim
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Publication number: 20230258680Abstract: A system and method for treatment of biological samples is disclosed. In some embodiments, an automated biological sample staining system (100), comprising at least one microfluidic reagent applicator (118); at least one bulk fluid applicator (116); at least one fluid aspirator; at least one sample substrate holder; at least one relative motion system; and a control system (102) that is programmed to execute at least one staining protocol on a sample mounted on a substrate that is held in the at least one sample substrate holder.Type: ApplicationFiled: April 20, 2023Publication date: August 17, 2023Inventors: Andreas Drechsler, Oliver Gutmann, Melis Hazar, Reto Huesser, Raymond T. Kozikowski, III, Daniel Mueller, Chris Steinert
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Patent number: 11668726Abstract: A system and method for treatment of biological samples is disclosed. In some embodiments, an automated biological sample staining system (100), comprising at least one microfluidic reagent applicator (118); at least one bulk fluid applicator (116); at least one fluid aspirator; at least one sample substrate holder; at least one relative motion system; and a control system (102) that is programmed to execute at least one staining protocol on a sample mounted on a substrate that is held in the at least one sample substrate holder.Type: GrantFiled: April 18, 2019Date of Patent: June 6, 2023Assignees: Ventana Medical Systems, Inc., Roche Diagnostics Operations, Inc.Inventors: Andreas Drechsler, Oliver Gutmann, Melis Hazar, Reto Huesser, Raymond T. Kozikowski, III, Daniel Mueller, Chris Steinert
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Patent number: 11226348Abstract: A storage module for a laboratory automation system, a method of operating a laboratory automation system, and a laboratory automation system are presented. Items used by laboratory stations are stored centrally in a storage module and can be transported to the laboratory stations using a laboratory sample distribution system.Type: GrantFiled: December 15, 2017Date of Patent: January 18, 2022Assignee: Roche Diagnostics Operations, Inc.Inventors: Urs Vollenweider, Gottlieb Schacher, Goran Savatic, Marco Maetzler, Christoph Ludwig, Christian Loewenstein, Yves Laloux, Rik Harbers, Matthias Edelmann, Andreas Drechsler
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Patent number: 11204361Abstract: A laboratory automation system for processing sample containers containing laboratory samples and/or for processing the samples is presented. The laboratory automation system comprises a digital camera configured to take an image of the sample container together with a calibration element. The image comprises image data related to the sample container and image data related to the calibration element. The laboratory automation system also comprises an image processing device configured to determine geometrical properties of the sample container depending on the image data related to the sample container and the image data related to the calibration element.Type: GrantFiled: January 19, 2018Date of Patent: December 21, 2021Assignee: Roche Diagnostics Operations, Inc.Inventors: Armin Birrer, Andreas Drechsler, Rik Harbers
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Publication number: 20210373042Abstract: A module for an automated laboratory system is disclosed. The module comprises a module connector configured to releasably connect to a component of the automated laboratory system, a detector at least configured to detect at least one component marker located at the component so as to obtain position data of the module indicating an actual position of the module, a processor configured to calculate a position deviation of the module from a target position defined by the component based on the position data and to calculate position alignment data based on the position deviation, and a alignment device configured to align the module to the target position based on the position alignment data. Further, an automated laboratory system and a method for aligning a module are disclosed.Type: ApplicationFiled: May 24, 2021Publication date: December 2, 2021Applicant: Roche Diagnostics Operations, Inc.Inventors: Claudio Cherubini, Andreas Drechsler, Reto Huesser, Ivan Heinzer
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Patent number: 11130710Abstract: A roofing tile composed of concrete material and a method for producing such a roofing tile. The concrete material contains a binder, a gravel, a light-weight aggregate, and added water. The roofing tile has at least one watercourse and a lateral interlocking joint having a covering fold and a water fold. The ratio of water to binder is less than 0.3, the light-weight aggregate is composed of a material that is hydrophobic and/or not hygroscopic, and the roofing tile has a density in the range of 1.6 g/cm3 to 1.9 g/cm3 after the hardening. The roofing tile has a thickness of 5 mm to 9 mm, preferably 7 mm to 8 mm, in the highly loaded regions, preferably in the region of the watercourse.Type: GrantFiled: February 14, 2018Date of Patent: September 28, 2021Inventors: Andreas Drechsler, Michael Friedrich, Michael Heise, Jürgen Klein, Stephan Westphal, Ben Cranfield
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Publication number: 20210283714Abstract: According to the present invention, a system (1; 1?) for processing at least one substrate (2) containing a dried fluid sample (21) is provided, the system (1; 1?) comprising a support (12) configured to position the substrate (2), a laser device (3) for directing a laser beam (31) to the substrate (2), configured to cut at least one area of the substrate (2) containing the dried fluid sample (21) by means of the laser beam (31), a container holder (4; 4?) configured to hold and position a container (5) for receiving the cut area, the container holder (4; 4?) being arranged below the substrate (2), and an extraction subsystem (6) for extracting fume and/or dust generated when laser cutting the substrate (2), wherein the extraction subsystem (6) consists of at least two extraction components (61, 62) sandwiching the substrate (2) there between. Furthermore, a method for automated processing at least one substrate (2) containing a dried fluid (21) sample by means of such a system (1; 1?) is provided.Type: ApplicationFiled: May 27, 2021Publication date: September 16, 2021Inventors: Claudio Cherubini, Andreas Drechsler, Reto Huesser, Emad Sarofim
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Patent number: 11112419Abstract: A laboratory distribution system is presented. The system comprises diagnostic laboratory container carriers and a conveyor. The conveyor comprises an endless drive defining a closed-loop conveyor pathway. The system comprises supporting elements attached to the endless drive. The supporting elements receive a container carrier and transport the container carrier in an upright position along a pathway section. The supporting elements are mounted pivotally about a horizontal pivot axis to the drive and structured such that a center of gravity of the supporting element with or without an empty or loaded container carrier is arranged below and vertically aligned with the pivot axis when the supporting element is in an upright position such that each supporting element is free to pivot about the associated pivot axis under the effect of gravitational forces acting on the supporting element for maintaining the supporting elements in an upright position while travelling along the path.Type: GrantFiled: July 10, 2018Date of Patent: September 7, 2021Assignee: Roche Diagnostics Operations, Inc.Inventors: Hans van Mierlo, Gottlieb Schacher, Marcel Kaeppeli, Reto Huesser, Andreas Drechsler, Matthias Goetz, Nenad Milicevic
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Patent number: 11067565Abstract: A device is described including a lid, a collection portion support, and a collection portion with a surface for receiving a biological sample, the lid includes a window and a window holder, the surface defines a first plane, the collection portion includes a first, a second, and a third position markers, each position marker indicates a center point marker, the center points define a second plane that has a line of intersection with the first plane, the device has an interior volume defined partially by the collection portion support, the collection portion, the window, and the window holder, the window allows visual inspection of the position markers, the collection portion support has a fluid inlet and a fluid outlet with a fluid path from the fluid inlet to the fluid outlet via the interior volume.Type: GrantFiled: March 16, 2018Date of Patent: July 20, 2021Assignee: Roche Molecular Systems, Inc.Inventors: Andreas Drechsler, Edwin Oosterbroek, Emad Sarofim, Heiko Schwertner
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Publication number: 20210213450Abstract: A method to process a laboratory carrier in a laboratory system based on a feature of a test liquid in the laboratory carrier is presented. The laboratory system comprises the laboratory carrier comprising the test liquid, a terahertz wave source, a terahertz detector, a laboratory carrier processing device, and a control unit. Using terahertz technology and data analysis, the feature of the test liquid in the laboratory carrier can be determined. In addition, the control unit controls the laboratory carrier processing device based on the determined feature of the test liquid.Type: ApplicationFiled: January 5, 2021Publication date: July 15, 2021Applicant: Roche Diagnostics Operations, Inc.Inventors: Andreas Drechsler, Darko Klinec, Michael Koehler, Alexander Jakob, Michael Zeder
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Patent number: 11052484Abstract: According to the present invention, a system (1; 1?) for processing at least one substrate (2) containing a dried fluid sample (21) is provided, the system (1; 1?) comprising a support (12) configured to position the substrate (2), a laser device (3) for directing a laser beam (31) to the substrate (2), configured to cut at least one area of the substrate (2) containing the dried fluid sample (21) by means of the laser beam (31), a container holder (4; 4?) configured to hold and position a container (5) for receiving the cut area, the container holder (4; 4?) being arranged below the substrate (2), and an extraction subsystem (6) for extracting fume and/or dust generated when laser cutting the substrate (2), wherein the extraction subsystem (6) consists of at least two extraction components (61, 62) sandwiching the substrate (2) there between. Furthermore, a method for automated processing at least one substrate (2) containing a dried fluid (21) sample by means of such a system (1; 1?) is provided.Type: GrantFiled: May 17, 2018Date of Patent: July 6, 2021Assignee: Roche Molecular Systems, Inc.Inventors: Claudio Cherubini, Andreas Drechsler, Reto Huesser, Emad Sarofim
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Publication number: 20210154684Abstract: A bucket insert for use in a centrifuge is disclosed. The bucket insert comprises an insert body, the insert body comprising a plurality of elongated receptacles for receiving elongated sample vessels. The bucket insert is configured for orienting the elongated sample vessels in a tilted orientation. In the tilted orientation, at least some of the elongated sample vessels are oriented in a non-parallel fashion.Type: ApplicationFiled: November 20, 2020Publication date: May 27, 2021Applicant: Roche Diagnostics Operations, Inc.Inventors: Claudio Cherubini, Andreas Drechsler
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Publication number: 20190242921Abstract: A system and method for treatment of biological samples is disclosed. In some embodiments, an automated biological sample staining system (100), comprising at least one microfluidic reagent applicator (118); at least one bulk fluid applicator (116); at least one fluid aspirator; at least one sample substrate holder; at least one relative motion system; and a control system (102) that is programmed to execute at least one staining protocol on a sample mounted on a substrate that is held in the at least one sample substrate holder.Type: ApplicationFiled: April 18, 2019Publication date: August 8, 2019Inventors: Andreas Drechsler, Oliver Gutmann, Melis Hazar, Reto Huesser, Raymond T. Kozikowski, III, Daniel Mueller, Chris Steinert
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Patent number: 10329198Abstract: A roofing tile composed of concrete material and a method for producing such a roofing tile. The concrete material contains a binder, a gravel, a light-weight aggregate, and added water. The roofing tile has at least one watercourse and a lateral interlocking joint having a covering fold and a water fold. The ratio of water to binder is less than 0.3, the light-weight aggregate is composed of a material that is hydrophobic and/or not hygroscopic, and the roofing tile has a density in the range of 1.6 g/cm3 to 1.9 g/cm3 after the hardening. The roofing tile has a thickness of 5 mm to 9 mm, preferably 7 mm to 8 mm, in the highly loaded regions, preferably in the region of the watercourse.Type: GrantFiled: February 15, 2016Date of Patent: June 25, 2019Assignee: Monier Roofing GmbHInventors: Andreas Drechsler, Michael Friedrich, Michael Heise, Jürgen Klein, Stephan Westphal, Ben Cranfield
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Publication number: 20180333806Abstract: According to the present invention, a system (1; 1?) for processing at least one substrate (2) containing a dried fluid sample (21) is provided, the system (1; 1?) comprising a support (12) configured to position the substrate (2), a laser device (3) for directing a laser beam (31) to the substrate (2), configured to cut at least one area of the substrate (2) containing the dried fluid sample (21) by means of the laser beam (31), a container holder (4; 4?) configured to hold and position a container (5) for receiving the cut area, the container holder (4; 4?) being arranged below the substrate (2), and an extraction subsystem (6) for extracting fume and/or dust generated when laser cutting the substrate (2), wherein the extraction subsystem (6) consists of at least two extraction components (61, 62) sandwiching the substrate (2) there between. Furthermore, a method for automated processing at least one substrate (2) containing a dried fluid (21) sample by means of such a system (1; 1?) is provided.Type: ApplicationFiled: May 17, 2018Publication date: November 22, 2018Inventors: Claudio Cherubini, Andreas Drechsler, Reto Huesser, Emad Sarofim
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Publication number: 20180224476Abstract: A laboratory automation system for processing sample containers containing laboratory samples and/or for processing the samples is presented. The laboratory automation system comprises a digital camera configured to take an image of the sample container together with a calibration element. The image comprises image data related to the sample container and image data related to the calibration element. The laboratory automation system also comprises an image processing device configured to determine geometrical properties of the sample container depending on the image data related to the sample container and the image data related to the calibration element.Type: ApplicationFiled: January 19, 2018Publication date: August 9, 2018Applicant: Roche Diagnostics Operations, Inc.Inventors: Armin Birrer, Andreas Drechsler, Rik Harbers
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Publication number: 20180209964Abstract: A device is described including a lid, a collection portion support, and a collection portion with a surface for receiving a biological sample, the lid includes a window and a window holder, the surface defines a first plane, the collection portion includes a first, a second, and a third position markers, each position marker indicates a center point marker, the center points define a second plane that has a line of intersection with the first plane, the device has an interior volume defined partially by the collection portion support, the collection portion, the window, and the window holder, the window allows visual inspection of the position markers, the collection portion support has a fluid inlet and a fluid outlet with a fluid path from the fluid inlet to the fluid outlet via the interior volume.Type: ApplicationFiled: March 16, 2018Publication date: July 26, 2018Applicant: Roche Molecular Systems, Inc.Inventors: Andreas Drechsler, Edwin Oosterbroek, Emad Sarofim, Heiko Schwertner
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Publication number: 20180170809Abstract: A roofing tile composed of concrete material and a method for producing such a roofing tile. The concrete material contains a binder, a gravel, a light-weight aggregate, and added water. The roofing tile has at least one watercourse and a lateral interlocking joint having a covering fold and a water fold. The ratio of water to binder is less than 0.3, the light-weight aggregate is composed of a material that is hydrophobic and/or not hygroscopic, and the roofing tile has a density in the range of 1.6 g/cm3 to 1.9 g/cm3 after the hardening. The roofing tile has a thickness of 5 mm to 9 mm, preferably 7 mm to 8 mm, in the highly loaded regions, preferably in the region of the watercourse.Type: ApplicationFiled: February 14, 2018Publication date: June 21, 2018Inventors: Andreas DRECHSLER, Michael FRIEDRICH, Michael HEISE, Jürgen KLEIN, Stephan WESTPHAL, Ben CRANFIELD