Patents by Inventor Andreas Ebneth

Andreas Ebneth has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MODIFIED OLIGONUCLEOTIDES FOR USE IN TREATMENT OF TAUOPATHIES
    Publication number: 20240011029
    Abstract: Oligonucleotides comprising modifications at the 2? and/or 3? positions(s) along with methods of making and use against Alzheimer disease and other tauopathies are disclosed.
    Type: Application
    Filed: September 26, 2022
    Publication date: January 11, 2024
    Inventors: Andreas EBNETH, Constantin VAN OUTRYVE D'YDEWALLE, Sergei GRYAZNOV, Saúl MARTINEZ MONTERO, Leonid BEIGELMAN, Vivek Kumar RAJWANSHI
  • Modified oligonucleotides for use in treatment of tauopathies
    Patent number: 11453881
    Abstract: Oligonucleotides comprising modifications at the 2? and/or 3? positions(s) along with methods of making and use against Alzheimer disease and other tauopathies are disclosed.
    Type: Grant
    Filed: March 13, 2019
    Date of Patent: September 27, 2022
    Assignee: Janssen Pharmaceutica NV
    Inventors: Andreas Ebneth, Constantin Van Outryve D'Ydewalle, Sergei Gryaznov, Saúl Martinez Montero, Leonid Beigelman, Vivek Kumar Rajwanshi
  • MODIFIED OLIGONUCLEOTIDES FOR USE IN TREATMENT OF TAUOPATHIES
    Publication number: 20210095284
    Abstract: Oligonucleotides comprising modifications at the 2 and/or 3? positions(s) along with methods of making and use against Alzheimer disease and other tauopathies are disclosed.
    Type: Application
    Filed: March 13, 2019
    Publication date: April 1, 2021
    Inventors: Andreas EBNETH, Constantin VAN OUTRYVE D'YDEWALLE, Sergei GRYAZNOV, Saúl MARTINEZ MONTERO, Leonid BEIGELMAN, Vivek Kumar RAJWANSHI
  • Method for Examining the Activity of Ion Channels
    Publication number: 20070281330
    Abstract: The present invention relates to a method for examining the activity of ion channels, comprising the following steps: providing a sample comprising ion channels; and determining a value of a measuring parameter as an indicator of the activity of the ion channels; characterized in that said determining of the value of the measuring parameter is performed at a temperature of ? about 10° C.
    Type: Application
    Filed: January 14, 2005
    Publication date: December 6, 2007
    Inventors: Andreas Ebneth, Rainer Netzer, Ulrike Hahn
  • Diagnostic and Therapeutic Use of the Human Dax-1 Gene and Protein for Neurodegenerative Diseases
    Publication number: 20070271619
    Abstract: The present invention discloses the differential expression of a cytosolic sulfotransferase in specific brain regions of Alzheimer's disease patients. Based on this finding, this invention provides a method for diagnosing or prognosticating a neurodegenerative disease, in particular Alzheimer's disease, in a subject, or for determining whether a subject is at increased risk of developing such a disease. Furthermore, this invention provides therapeutic and prophylactic methods for treating or preventing Alzheimer's disease and related neurodegenerative disorders using a gene coding for DAX-1. A method of screening for modulating agents of neurodegenerative diseases and recombinant animal models are also disclosed.
    Type: Application
    Filed: October 28, 2004
    Publication date: November 22, 2007
    Inventors: Heinz Von Der Kammer, Johannes Pohlner, Thomas Hesterkamp, Andreas Ebneth