Patents by Inventor Andreas Eckelt

Andreas Eckelt has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Enrichment and identification of fetal cells in maternal blood and ligands for such use
    Patent number: 9429520
    Abstract: The present invention relates to enrichment and/or identification of fetal cells of a maternal blood sample using fetal cell specific ligands and/or fetal cell specific hybridization probes wherein the ligand or probes are directed to an endothelial/mesenchymal marker, e.g. CD105, CD146 or CD141, in a first round of enrichment and the ligand or probes, in a second round of enrichment, are directed to an epithelial marker, e.g. a cytokeratin, such as CK7, CK8, CK18 or CK19. Enriched or identified fetal cells may be subjected to steps of detection or diagnosis, wherefore the present invention enables non-invasive 5 prenatal diagnostics.
    Type: Grant
    Filed: November 9, 2011
    Date of Patent: August 30, 2016
    Assignee: Arcedi Biotech ApS
    Inventors: Andreas Eckelt, Britta Christensen, Steen Kolvraa, Marie Brinch, Ripudaman Singh, Lotte Hatt
  • ENRICHMENT AND IDENTIFICATION OF FETAL CELLS IN MATERNAL BLOOD AND LIGANDS FOR SUCH USE
    Publication number: 20130331284
    Abstract: The present invention relates to enrichment and/or identification of fetal cells of a maternal blood sample using fetal cell specific ligands and/or fetal cell specific hybridization probes wherein the ligand or probes are directed to an endothelial/mesenchymal marker, e.g. CD105, CD146 or CD141, in a first round of enrichment and the ligand or probes, in a second round of enrichment, are directed to an epithelial marker, e.g. a cytokeratin, such as CK7, CK8, CK18 or CK19. Enriched or identified fetal cells may be subjected to steps of detection or diagnosis, wherefore the present invention enables non-invasive 5 prenatal diagnostics.
    Type: Application
    Filed: November 9, 2011
    Publication date: December 12, 2013
    Inventors: Andreas Eckelt, Marie Brinch, Britta Christensen, Ripudaman Singh, Steen Kølvraa, Lotte Hatt
  • ENRICHMENT AND IDENTIFICATION OF FETAL CELLS IN MATERNAL BLOOD AND LIGANDS FOR SUCH USE
    Publication number: 20120003643
    Abstract: The present invention relates to enrichment and/or identification of fetal cells of a maternal blood sample using fetal cell specific ligands and/or fetal cell specific hybridization probes. Enriched or identified fetal cells may be subjected to steps of detection or diagnosis, wherefore the present invention enables non-invasive prenatal diagnostics.
    Type: Application
    Filed: January 7, 2010
    Publication date: January 5, 2012
    Applicant: FCMB APS
    Inventors: Britta Christensen, Steen Kølvraa, Andreas Eckelt, Marie Brinch, Ripudaman Singh, Lotte Hatt