Patents by Inventor Andreas Ehlich

Andreas Ehlich has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Assay for drug discovery based on in vitro differentiated cells
    Patent number: 9726662
    Abstract: Provided are assay systems for determining the therapeutic or toxic effect of a putative drug based on assaying its activity in cells which have been differentiated in vitro from stem cells, and induced to display a phenotype that resembles a disease to be treated.
    Type: Grant
    Filed: January 15, 2016
    Date of Patent: August 8, 2017
    Assignee: AXIOGENESIS AG
    Inventors: Heribert Bohlen, Kristina Jönsson, Andreas Ehlich, Silke Schwengberg
  • TISSUE MODELING IN EMBRYONIC STEM (ES) CELL SYSTEM
    Publication number: 20170160259
    Abstract: Provided are embryonic stem (ES) cell-derived tissue modeling systems. In particular, systems for the de novo generation of tissue by parallel drug selection of cell types constituting the tissue of interest in one culture of differentiating ES cells is described as well as the use of such systems in transplantation and drug development.
    Type: Application
    Filed: February 18, 2016
    Publication date: June 8, 2017
    Applicant: AXIOGENESIS AG
    Inventors: EUGEN KOLOSSOV, Jürgen Hescheler, Heribert Bohlen, Bernd Fleischmann, Wilhelm Röll, Andreas Ehlich, Jessica Königsmann
  • ASSAY FOR DRUG DISCOVERY BASED ON IN VITRO DIFFERENTIATED CELLS
    Publication number: 20160209399
    Abstract: Provided are assay systems for determining the therapeutic or toxic effect of a putative drug based on assaying its activity in cells which have been differentiated in vitro from stem cells, and induced to display a phenotype that resembles a disease to be treated.
    Type: Application
    Filed: January 15, 2016
    Publication date: July 21, 2016
    Applicant: AXIOGENESIS AG
    Inventors: Heribert Bohlen, Kristina Jönsson, Andreas Ehlich, Silke Schwengberg
  • Tissue modeling in embryonic stem (ES) cell system
    Patent number: 9321997
    Abstract: Provided are embryonic stem (ES) cell-derived tissue modeling systems. In particular, systems for the de novo generation of tissue by parallel drug selection of cell types constituting the tissue of interest in one culture of differentiating ES cells is described as well as the use of such systems in transplantation and drug development.
    Type: Grant
    Filed: June 21, 2004
    Date of Patent: April 26, 2016
    Assignee: AXIOGENESIS AG
    Inventors: Eugen Kolossov, Jürgen Hescheler, Heribert Bohlen, Bernd Fleischmann, Wilhelm Röll, Andreas Ehlich, Jessica Königsmann
  • Assay for drug discovery based on in vitro differentiated cells
    Patent number: 8318488
    Abstract: Provided are assay systems for determining the therapeutic or toxic effect of a putative drug based on assaying its activity in cells which have been differentiated in vitro from stem cells, and induced to display a phenotype that resembles a disease to be treated.
    Type: Grant
    Filed: May 11, 2005
    Date of Patent: November 27, 2012
    Assignee: Axiogenesis AG
    Inventors: Heribert Bohlen, Kristina Jönsson, Andreas Ehlich, Silke Schwengberg
  • Secreted proteins as markers for cell differentiation
    Publication number: 20090328243
    Abstract: Provided are means and methods for in vitro and in vivo detection of chemically induced effects on embryonic development and differentiation for the purpose of embryotoxicity/teratogenicity screening as well as for the identification of pharmaceuticals such as growth and tissue promoting factors based on differentiating pluripotent embryonic stem (ES) cells. The assays are based on the use of transgenic ES cells and non-human animals comprising such ES cells or derivatives thereof, wherein said ES cells are characterized by the differentiation-dependent expression of a secreted reporter protein; in particular secreted embryonic alkaline phosphatase (SEAP).
    Type: Application
    Filed: July 8, 2004
    Publication date: December 31, 2009
    Inventor: Andreas Ehlich
  • Tissue Modeling in Embryonic Stem (Es) Cell System
    Publication number: 20070258948
    Abstract: Provided are embryonic stem (ES) cell-derived tissue modeling systems. In particular, systems for the de novo generation of tissue by parallel drug selection of cell types constituting the tissue of interest in one culture of differentiating ES cells is described as well as the use of such systems in transplantation and drug development.
    Type: Application
    Filed: June 21, 2004
    Publication date: November 8, 2007
    Applicant: Axiogenesis AG
    Inventors: Eugen Kolossov, Jurgen Hescheler, Heribert Bohlen, Bernd Fleischmann, Wilhelm Roll, Andreas Ehlich, Jessica Konigsmann