Patents by Inventor Andreas G. GRILL

Andreas G. GRILL has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PHARMACEUTICALLY ACCEPTABLE SALTS OF BETA-GUANIDINOPROPIONIC ACID WITH IMPROVED PROPERTIES AND USES THEREOF
    Publication number: 20200138759
    Abstract: The present invention relates to new pharmaceutical salts of ?-GPA which exhibit improved physical properties. In particular, the invention relates to salts of ?-GPA with improved flow properties (e.g., improved Carr's index and/or Hausner ratio) such as fumarate salts, succinate salts, and oxalate salts. The invention also relates to pharmaceutical compositions including a pharmaceutically effective amount of one or more salts of ?-GPA, as well as methods of treating cancer including administration of a formulation including a ?-GPA salt of the invention to a subject in need thereof.
    Type: Application
    Filed: November 6, 2019
    Publication date: May 7, 2020
    Inventors: Eduardo J. MARTINEZ, Andreas G. GRILL, Aniruddh SINGH, Padmini KAVURU
  • Pharmaceutically acceptable salts of B-Guanidinopropionic acid with improved properties and uses thereof
    Patent number: 10512623
    Abstract: The present invention relates to new pharmaceutical salts of ?-GPA which exhibit improved physical properties. In particular, the invention relates to salts of ?-GPA with improved flow properties (e.g., improved Carr's index and/or Hausner ratio) such as fumarate salts, succinate salts, and oxalate salts. The invention also relates to pharmaceutical compositions including a pharmaceutically effective amount of one or more salts of ?-GPA, as well as methods of treating cancer including administration of a formulation including a ?-GPA salt of the invention to a subject in need thereof.
    Type: Grant
    Filed: October 27, 2017
    Date of Patent: December 24, 2019
    Assignee: Rgenix, Inc.
    Inventors: Eduardo J. Martinez, Andreas G. Grill, Aniruddh Singh, Padmini Kavuru
  • PHARMACEUTICALLY ACCEPTABLE SALTS OF B-GUANIDINOPROPIONIC ACID WITH IMPROVED PROPERTIES AND USES THEREOF
    Publication number: 20180243248
    Abstract: The present invention relates to new pharmaceutical salts of ?-GPA which exhibit improved physical properties. In particular, the invention relates to salts of ?-GPA with improved flow properties (e.g., improved Carr's index and/or Hausner ratio) such as fumarate salts, succinate salts, and oxalate salts. The invention also relates to pharmaceutical compositions including a pharmaceutically effective amount of one or more salts of ?-GPA, as well as methods of treating cancer including administration of a formulation including a ?-GPA salt of the invention to a subject in need thereof.
    Type: Application
    Filed: October 27, 2017
    Publication date: August 30, 2018
    Inventors: Eduardo J. MARTINEZ, Andreas G. GRILL, Aniruddh SINGH, Padmini KAVURU
  • Pharmaceutically acceptable salts of B-guanidinopropionic acid with improved properties and uses thereof
    Patent number: 9884813
    Abstract: The present invention relates to new pharmaceutical salts of ?-GPA which exhibit improved physical properties. In particular, the invention relates to salts of ?-GPA with improved flow properties (e.g., improved Carr's index and/or Hausner ratio) such as fumarate salts, succinate salts, and oxalate salts. The invention also relates to pharmaceutical compositions including a pharmaceutically effective amount of one or more salts of ?-GPA, as well as methods of treating cancer including administration of a formulation including a ?-GPA salt of the invention to a subject in need thereof.
    Type: Grant
    Filed: March 3, 2017
    Date of Patent: February 6, 2018
    Assignee: Rgenix, Inc.
    Inventors: Eduardo J. Martinez, Andreas G. Grill, Aniruddh Singh, Padmini Kavuru, Nicholas D. Paschalides, Stephen A. Wald
  • Pharmaceutically acceptable salts of B-guanidinopropionic acid with improved properties and uses thereof
    Patent number: 9827217
    Abstract: The present invention relates to new pharmaceutical salts of ?-GPA which exhibit improved physical properties. In particular, the invention relates to salts of ?-GPA with improved flow properties (e.g., improved Carr's index and/or Hausner ratio) such as fumarate salts, succinate salts, and oxalate salts. The invention also relates to pharmaceutical compositions including a pharmaceutically effective amount of one or more salts of ?-GPA, as well as methods of treating cancer including administration of a formulation including a ?-GPA salt of the invention to a subject in need thereof.
    Type: Grant
    Filed: September 30, 2016
    Date of Patent: November 28, 2017
    Assignee: Rgenix, Inc.
    Inventors: Eduardo J. Martinez, Andreas G. Grill, Aniruddh Singh, Padmini Kavuru
  • PHARMACEUTICALLY ACCEPTABLE SALTS OF ss-GUANIDINOPROPIONIC ACID WITH IMPROVED PROPERTIES AND USES THEREOF
    Publication number: 20170056353
    Abstract: The present invention relates to new pharmaceutical salts of ?-GPA which exhibit improved physical properties. In particular, the invention relates to salts of ?-GPA with improved flow properties (e.g., improved Carr's index and/or Hausner ratio) such as fumarate salts, succinate salts, and oxalate salts. The invention also relates to pharmaceutical compositions including a pharmaceutically effective amount of one or more salts of ?-GPA, as well as methods of treating cancer including administration of a formulation including a ?-GPA salt of the invention to a subject in need thereof.
    Type: Application
    Filed: September 30, 2016
    Publication date: March 2, 2017
    Inventors: Eduardo J. MARTINEZ, Andreas G. GRILL, Aniruddh SINGH, Padmini KAVURU
  • PHARMACEUTICALLY ACCEPTABLE SALTS OF beta-GUANIDINOPROPIONIC ACID WITH IMPROVED PROPERTIES AND USES THEREOF
    Publication number: 20170056352
    Abstract: The present invention relates to new pharmaceutical salts of ?-GPA which exhibit improved physical properties. In particular, the invention relates to salts of ?-GPA with improved flow properties (e.g., improved Carr's index and/or Hausner ratio) such as fumarate salts, succinate salts, and oxalate salts. The invention also relates to pharmaceutical compositions including a pharmaceutically effective amount of one or more salts of ?-GPA, as well as methods of treating cancer including administration of a formulation including a ?-GPA salt of the invention to a subject in need thereof.
    Type: Application
    Filed: August 24, 2016
    Publication date: March 2, 2017
    Inventors: Eduardo J. MARTINEZ, Andreas G. GRILL, Aniruddh SINGH, Padmini KAVURU