Abstract: The present invention relates to a computer implemented method for determining a weld integrity test result performed by a system configured to aseptically transferring cells to a container (BR), the method comprising welding (710) a vial to a connector to obtain a fluid-tight seal between the vial (V) and a connector (C), the connector being provided with a pair of conduits each having one end protruding through the connector and into the vial, sealing (720) an opposite end of one of the conduits, generating (730) a fluid pressure different to an ambient fluid pressure at an opposite end of the other conduit, measuring (740) a fluid pressure within at least one of the conduits, determining (750) a fluid pressure change based on the ambient pressure and the measured fluid pressure, determining (760) the weld integrity test result as pass or as fail based on the fluid pressure change.

Abstract: A pressure plate assembly for a friction clutch with automatic wear compensation, including a housing which can be attached to a flywheel for rotation in common; a pressure plate installed in the housing and movable axially with respect to the housing; and an energy storage device supported against the housing and the pressure plate and exerting a force along a support path between the energy storage device and the pressure plate. A wear take-up device installed in the support path includes a wear take-up element which is preloaded to move in a wear take-up direction. An anti-reset device includes at least one clamping element which can be blocked to generate clamping contact with the wear take-up element, thereby preventing movement of the wear take-up element relative to the pressure plate in a direction opposite to the wear take-up direction.

Abstract: A friction clutch arrangement includes a clutch housing mounted to a flywheel, a pressure plate, a clutch disk mounted on a transmission shaft, and a diaphragm spring which loads the pressure plate toward the flywheel to engage the clutch. A disengagement device includes a sliding sleeve which is axially displaceable on the shaft to introduce a disengagement force to the clutch spring via an force action point, thereby producing a characteristic curve of disengagement force versus disengagement travel of the sleeve. During disengagement, a compensation device introduces a compensation force counter to the pressing force in a predefined section of the characteristic curve, thereby reducing the disengagement force in the predefined section. A switchable force transmission device changes the effective force transmission ratio of the pressing force and the disengagement force during disengagement in a predetermined manner, thereby optimizing the disengagement stroke of the pressure plate.

Abstract: The present invention provides calixpyrrole, calixpyridinopyrrole, and calixpyridine macrocycles, having 4, 5, 6, 7, or 8 heterocyclic rings, as well as syntheses, derivatives, conjugates, multimers, and solid supports thereof. Such macrocycles have proved to be effective and selective ion- and neutral molecule-binding agents forming supramolecular ensembles, and ion- and neutral molecule-separation agents. The macrocycles are fully meso-non-hydrogen-substituted porphyrinogens, a few molecules of which were previously known but not recognized as possessing anion- or molecule-binding properties. The binding mode is noncovalent, primarily that of hydrogen-bonding, thereby providing a new mode for liquid chromatography, that of Hydrogen Bonding Liquid Chromatography. Further useful applications of the macrocycles provided herein include environmental remediation by removal of undesired ions or neutral molecules, and removal of phosphate for kidney dialysis.

Abstract: A friction clutch arrangement includes a clutch housing mounted to a flywheel, a pressure plate, a clutch disk mounted on a transmission shaft, and a diaphragm spring which loads the pressure plate toward the flywheel to engage the clutch. A disengagement device includes a sliding sleeve which is axially displaceable on the shaft to introduce a disengagement force to the clutch spring via an force action point, thereby producing a characteristic curve of disengagement force versus disengagement travel of the sleeve. During disengagement, a compensation device introduces a compensation force counter to the pressing force in a predefined section of the characteristic curve, thereby reducing the disengagement force in the predefined section. A switchable force transmission device changes the effective force transmission ratio of the pressing force and the disengagement force during disengagement in a predetermined manner, thereby optimizing the disengagement stroke of the pressure plate.

Abstract: The present invention provides calixpyrrole, calixpyridinopyrrole, and calixpyridine macrocycles, having 4, 5, 6, 7, or 8 heterocyclic rings, as well as syntheses, derivatives. conjugates, multimers, and solid supports thereof. Such macrocycles have proved to be effective and selective ion- and neutral molecule-binding agents forming supramolecular ensembles, and ion- and neutral molecule-separation agents. The macrocycles are fully meso-non-hydrogen-substituted porphyrinogens, a few molecules of which were previously known but not recognized as possessing anion- or molecule-binding properties. The binding mode is noncovalent, primarily that of hydrogen-bonding, thereby providing a new mode for liquid chromatography, that of Hydrogen Bonding Liquid Chromatography. Further useful applications of the macrocycles provided herein include environmental remediation by removal of undesired ions or neutral molecules, and removal of phosphate for kidney dialysis.

Abstract: The present invention provides calixpyrrole, calixpyridinopyrrole, and calixpyridine macrocycles, having 4, 5, 6, 7, or 8 heterocyclic rings, as well as syntheses, derivatives, conjugates, multimers, and solid supports thereof. Such macrocycles have proved to be effective and selective ion- and neutral molecule-binding agents forming supramolecular ensembles, and ion- and neutral molecule-separation agents. The macrocycles are fully meso-non-hydrogen-substituted porphyrinogens, a few molecules of which were previously known but not recognized as possessing anion- or molecule-binding properties. The binding mode is noncovalent, primarily that of hydrogen-bonding, thereby providing a new mode for liquid chromatography, that of Hydrogen Bonding Liquid Chromatography. Further useful applications of the macrocycles provided herein include environmental remediation by removal of undesired ions or neutral molecules, and removal of phosphate for kidney dialysis.

Abstract: A flywheel assembly has a first flywheel which is detachably connected to the crankshaft of a combustion engine, a second flywheel which can be rotated relative to the first, and a torque transformer, such as a hub disc, which is located in a chamber between the two flywheels, which chamber is filled with a viscous medium and which torque transformer is equipped with a torsion damping unit. The chamber is defined on that side facing the second flywheel by a cover plate, which encloses an air channel between it and the second flywheel, which air channel extends radially outward from a ventilation opening in the second flywheel. The torque transformer is provided radially outward from the ventilation opening with an annular surface, which annular surface extends preferably in the axial direction.

Abstract: A system of fastening a flywheel on an output end of a crankshaft of an internal combustion engine, the flywheel being combined into a single component with a clutch plate unit and a clutch disc. The fastening can be achieved with essentially axial joint surfaces on the output end on one hand, and on the flywheel on the other hand, wherein the joint surfaces are designed as tapered or cylindrical surfaces which are self-locking in the axial direction.

Abstract: The invention relates to a process for producing polyacrylic acids and copolymers of acrylic acid with up to 50 mol-% of comonomers. These compounds have a molecular weight of less than 100,000, measured at a pH-value of 8, and 10 to 60 mol-% are neutralized with calcium hydroxide. The invention also relates to the use of these products as grinding and dispersing aids for calcium carbonate.

Abstract: The invention relates to a process for producing polyacrylic acids and copolymers of acrylic acid with up to 50 mol-% of comonomers. These compounds have a molecular weight of less than 100,000, measured at a pH-value of 8, and 10 to 60 mol-% are neutralized with calcium hydroxide. The invention also relates to the use of these products as grinding and dispersing aids for calcium carbonate.