Abstract: The present disclosure relates to methods for treating or preventing or delaying progression or reducing or inhibiting or hindering development of a complication associated with sickle cell disease in a subject suffering from sickle cell disease, the method comprising administering to the subject a compound that inhibits granulocyte colony stimulating factor (G-CSF) signaling and/or G-CSF activity.

Abstract: Reconstituted HDL formulations, methods of treatment comprising same and uses thereof are provided for treating patients after an acute myocardial infarction (MI) event. The reconstituted HDL formulations comprise an apo lipoprotein, a lipid, a detergent and a stabilizer such as sucrose. Treatment of MI patients with repeated infusions of rHDL enhance cholesterol efflux capacity and do not produce significant alterations in liver or kidney function. The MI patient may have normal kidney function or moderate renal impairment.

Abstract: Reconstituted HDL formulations, methods of treatment comprising same and uses thereof are provided for treating patients after an acute myocardial infarction (MI) event. The reconstituted HDL formulations comprise an apo lipoprotein, a lipid, a detergent and a stabilizer such as sucrose. Treatment of MI patients with repeated infusions of rHDL enhance cholesterol efflux capacity and do not produce significant alterations in liver or kidney function. The MI patient may have normal kidney function or moderate renal impairment.

Abstract: The invention relates to oxazolopyrimidine compounds of formula (I), where A, R1, R2, R3, R4, X and Y are defined as stated in the claims. The compounds of formula I are suitable, for example, for wound healing.

Abstract: The invention relates to oxazolopyrimidine compounds of formula (I), where A, R1, R2 and R3 are defined as stated in the claims. The compounds of formula (I) are suitable, for example, for wound healing.

Abstract: The invention relates to oxazolopyrimidine compounds of formula (I), where A, R1, R2, R3, R4 and X are defined as stated in the claims. The compounds of formula I are suitable, for example, for wound healing.

Abstract: The invention relates to oxazolopyrimidine compounds of formula (I), where A, R1, R2, R3, R4, X and Y are defined as stated in the claims. The compounds of formula I are suitable, for example, for wound healing.

Abstract: The invention relates to oxazolopyrimidine compounds of formula (I), where A, R1, R2 and R3 are defined as stated in the claims. The compounds of formula (I) are suitable, for example, for wound healing.

Abstract: The invention relates to oxazolopyrimidine compounds of formula (I), where A, R1, R2, R3, R4 and X are defined as stated in the claims. The compounds of formula I are suitable, for example, for wound healing.

Abstract: The invention relates to a medical device for infusion of an active ingredient or removal of a body tissue or body liquid comprising: a outlet device for infusion of an active ingredient to a body tissue; a receptacle for storing the active ingredient to which the outlet device is attachable; a sensor device for measuring a parameter which is related to a physical state in the body tissue; a drive device for effectuating at least an infusion of the active ingredient; characterized by a control unit functionally connected to the sensor device for receiving a sensor signal, which corresponds to the state of the body tissue, wherein the control unit is adapted for controlling a flow rate.

Abstract: Light-sensitive sensor unit, especially for the automatic switching of illuminating equipment, preferably in motor vehicles, which includes at least two light-sensitive sensors, at least a first sensor and a second sensor detecting the light conditions in predetermined directions. For this purpose, all light-conducting elements allocated to the sensors are to be connected in one piece as a light-conducting member and integrated into the light-conducting member of a rain sensor.

Abstract: A sensor arrangement for detecting a wetting, in particular a precipitation and dirt accumulation, on a window (13) is proposed, with at least one transmitter (14) and at least one receiver (15) for the transmitter light (17) emitted by the transmitters (14), where the transmitters (14) and receivers (15) are disposed on the vertex points of an imaginary trapezoid. As a result, the external dimensions of the sensor are reduced, the ratio of sensitive area (19) and base area (18) of the sensor is improved, and a coherent sensitive area is produced, where there is also space available for a receiving element of an automatic light control.