Abstract: The invention relates to devices and methods for desorption scanning of analyte material deposited on a sample support, which can comprise the following mode of operation: (a) setting a position of the support to approach an impingement region onto which a beam is directed for local desorption of analyte material; (b) determining an actual position of the support after setting the position; (c) comparing the determined actual position with a target position of the support to determine any deviation; (d) adjusting a beam orientation, if a deviation is detected, so that the beam is directed onto the impingement region on the support that results when there is no deviation; (e) applying the beam to the impingement region to locally desorb analyte material and deliver it to an analyzer; and (f) checking whether a predetermined end condition is satisfied and, if not, repeating steps (a)-(e) for a subsequent non-congruent impingement region.

Abstract: A basket device for arrangement in a washing compartment of a dishwasher includes: a main body movable out of a washing position in the washing compartment into a loading position moved out at least partially of the washing compartment and vice versa; and a pull-out arranged on the main body so as to be displaceable in a movement direction of the main body, the pull-out being accommodating a first dish rack. The main body carries a second dish rack. The second dish rack is arranged on the main body so as to be displaceable both in the movement direction of the main body and transversely thereto in a vertical direction of the washing compartment.

Abstract: The present invention includes a ladder step extender that when in place on a ladder extends the area where a ladder user can place his feet, providing increased stability and comfort for the user. The ladder extender comprises two hanging arms, a horizontal stepping platform, and two ladder rung holders. The extender is secured to the ladder rungs by the hanging rods placed on an upper ladder rung while the rung holders engage a lower rung. When the extender is secured to a ladder, the horizontal stepping platform extends towards the interior or toe side of the ladder and extends the area where the ladder user's foot or feet may be placed.

Abstract: Disclosed is a method for analytically measuring sample material deposited on a sample support surface, comprising: (a) defining a plurality of regions on the surface, several of which are in contact with sample material, (b1) sampling sections of sample on a region using a desorbing beam to generate desorbed molecules, which are ionized and transferred to an analyzer, (b2) in so doing, sweeping the region by changing an orientation setting of the beam relative to the surface along a non-rectilinear trajectory on the region selected from a plurality of predefined, non-rectilinear trajectories while keeping the support in one position, (c) transitioning from a swept region to a region to be swept next using spatial adjustment of the support, and (d) repeating steps (b1), (b2), and (c) until a predetermined termination condition is fulfilled. A system for analyzing ions, having an ion generation device and a control unit is also disclosed.

Abstract: The invention relates to a test bed and a method for testing a real test object in driving operation, wherein the test object has at least one real component of a vehicle which is capable of applying torque to a wheel hub. The test bed comprises a load machine configured to be connected to the wheel hub so as to transmit torque, an actuator configured to generate a relative movement between the wheel hub on the one hand and a vehicle frame supporting the wheel hub on the other, simulation means for simulating the driving operation, wherein the simulation means is configured to simulate a virtual wheel and dynamics of the virtual wheel as if it were arranged on the wheel hub, and control means configured to operate the real test object in consideration of the simulated dynamics of the virtual wheel on the test bed.

Abstract: The disclosure relates to a method of operating a secondary-electron multiplier in the ion detector of a mass spectrometer so as to prolong the service life, wherein the secondary-electron multiplier is supplied with an operating voltage in such a way that an amplification of less than 106 secondary electrons per impinging ion results, while the output current of the secondary-electron multiplier is amplified using an electronic preamplifier mounted close to the secondary-electron multiplier with such a low noise level that the current pulses of individual ions impinging on the ion detector are detected above the noise at the input of a digitizing unit. Further disclosed are the use of the methods for imaging mass spectrometric analysis of a thin tissue section or mass spectrometric high-throughput analysis/massive-parallel analysis, and a time-of-flight mass spectrometer whose control unit is programmed to execute such methods.

Abstract: A device for coupling to a spindle of a machine tool includes a holder for coupling to the spindle of the machine tool, a conveyor element configured to convey a filament and rotatable about an axis of rotation, and a material processing unit. The material processing unit includes a gear which includes a force-receiving element configured to receive a mechanical force from the spindle and rotatable about an axis of rotation which extends substantially orthogonal to the axis of rotation of the conveyor element, and a force-delivery element configured to deliver to the conveyor element the mechanical force transmitted purely mechanically from the force-receiving element, with the force-receiving element being configured separately from the force-delivery element.

Abstract: The invention relates to aprocess for producing a catalyst comprising an intermetallic com-pound comprisingmixing of a salt comprising a metal selected from the group consisting of Co, Rh, Ir, Ni, Pd, Pt, Cu, Ag, Auand Ru, a salt comprising a metal selected from the group consist-ing of Li, Na, K, Rb, Cs, Be, Mg, Ca, Sr, Ba,Sc, Y, La and the lanthanides, and a reducing agentcomprising a salt,wherein the mixing is carried out at a temperature where all compo-nents are solid; reacting the mixture obtained to form an intermetallic compound by heating said to a temperature in the range between the melting temperature of thereducing agent and the melting temperature of the intermetallic compound and holdingthe temperaturefor1 minute to 600 minutes; and washing the mixture to removeby-products andremainders of the salt of the cations of the reducing agent and at least one of the anions of the salts used in the first step. The invention further relates to a catalyst obtained by the process.

Abstract: A package that includes an integrated device, a substrate coupled to the integrated device, and an encapsulation layer coupled to the substrate. The encapsulation layer encapsulates the integrated device. The substrate includes at least one dielectric layer, a plurality of interconnects located in the at least one dielectric layer, a buffer dielectric layer coupled to the at least one dielectric layer, and a buffer interconnect located at least in the buffer dielectric layer.

Abstract: The invention relates to imaging mass spectrometry on thin sample sections, in particular using MALDI, where a high lateral image resolution means that a plethora of mass spectra has to be acquired and the image acquisition runs over many hours. The quality of the mass spectra deteriorates considerably over time in such cases. The invention is based on the finding that the decrease in spectral quality of continuous measurement series over many hours is only partially caused by a decrease in detector gain, and that another significant cause is a decrease in the number of usable ions per ion generating pulse, which is attributable to several phenomena that are difficult to regulate. The invention now proposes to instead regulate only the detector gain, and such that not only the decrease in the detector gain is compensated, but also the decrease in the number of usable ions per ion generating pulse.

Abstract: The disclosure relates to a method of operating a secondary-electron multiplier in the ion detector of a mass spectrometer so as to prolong the service life, wherein the secondary-electron multiplier is supplied with an operating voltage in such a way that an amplification of less than 106 secondary electrons per impinging ion results, while the output current of the secondary-electron multiplier is amplified using an electronic preamplifier mounted close to the secondary-electron multiplier with such a low noise level that the current pulses of individual ions impinging on the ion detector are detected above the noise at the input of a digitizing unit. Further disclosed are the use of the methods for imaging mass spectrometric analysis of a thin tissue section or mass spectrometric high-throughput analysis/massive-parallel analysis, and a time-of-flight mass spectrometer whose control unit is programmed to execute such methods.

Abstract: The invention relates to the operation of an energy-focusing and solid-angle-focusing reflector for time-of-flight mass spectrometers with pulsed ion acceleration into a flight tube, e.g. from an ion source with ionization by matrix-assisted laser desorption (MALDI). The objective of the invention is to generate high mass resolution in wide mass ranges up to high masses above eight kilodaltons by varying at least one operating voltage on one of the diaphragms of the reflector which can be varied according to a suitable time function during the spectrum acquisition. It may also be advantageous to adapt the operation of the accelerating voltages in the starting region of the ions accordingly. These measures make it possible to achieve a mass resolution much higher than R=100,000 in a wide mass range extending up to and above eight kilodaltons.

Abstract: A mixer for mixing an exhaust gas flow with a fluid injected into an exhaust gas line comprises means for generating a swirl effecting a rotating flow and means for a radial displacement in the exhaust gas flow admixed with the fluid and flowing axially through the mixer. In this respect, the swirl generation means and the radial displacement means are arranged and designed such that, viewed over the cross-section of the mixer perpendicular to the axial exhaust gas flow, at least two separate swirl regions result which are built up via tangentially acting vane-like swirl elements and at least one respective radial displacement region results which is arranged between two separate swirl regions.

Abstract: The invention relates to a mass spectrometer with laser-desorption ion source, particularly for MALDI. A laser system with optical laser spot control is proposed in which the laser spot shift brought about by means of a temporally variable angular deflection at a mirror system is performed on the laser beam before or during the energy multiplication. The laser beam, which is deflected through a small angle by the mirror system, is converted by a suitable flat-field optical system into a parallel-shifted laser beam, which then passes through a multiplier crystal. After exiting the multiplier crystal system, the parallel-shifted beam is converted back into a slightly angled beam by a flat-field optical system, this latter beam then bringing about the spot shift on the sample. The multiplier crystal is conserved by the continuously temporally changed parallel shift of the laser beam in the multiplier crystal, thus prolonging its service life.

Abstract: The invention relates to the operation of an energy-focusing and solid-angle-focusing reflector for time-of-flight mass spectrometers with pulsed ion acceleration into a flight tube, e.g. from an ion source with ionization by matrix-assisted laser desorption (MALDI). The objective of the invention is to generate high mass resolution in wide mass ranges up to high masses above eight kilodaltons by varying at least one operating voltage on one of the diaphragms of the reflector which can be varied according to a suitable time function during the spectrum acquisition. It may also be advantageous to adapt the operation of the accelerating voltages in the starting region of the ions accordingly. These measures make it possible to achieve a mass resolution much higher than R=100,000 in a wide mass range extending up to and above eight kilodaltons.

Abstract: The present invention relates to a catalyst composition, comprising tin oxide particles which are at least partially coated by a noble metal oxide layer, wherein the composition contains iridium and ruthenium in a total amount of from 10 wt % to 38 wt %, and all iridium and ruthenium is oxidized, has a BET surface area of from 5 to 95 m2/g, and has an electrical conductivity at 25° C. of at least 7 S/cm.

Abstract: The invention relates to a process for producing a catalyst comprising an intermetallic compound comprising following steps: (a) Dissolving a metal selected from the group consisting of Li, Na, Ca, Sr, Ba, Eu and Yb in liquid ammonia, (b) Adding nanoparticles comprising a metal selected from the group consisting of Co, Rh, Ir, Ni, Pd, Pt, Cu, Ag, Au and Ru or a halide of at least one of these metals and an inorganic salt to the solution obtained in step (a), (c) Removing the liquid ammonia, (d) Annealing the mixture of step (c) at a temperature in the range between 200° C. and the melting temperature of the intermetallic compound wherein the intermetallic compound is formed, (e) Washing the intermetallic compound achieved in step (d). The invention further relates to a catalyst obtained by the process.

Abstract: The subject of the invention is a method for regulating the operation of a stripping device on a conveyor belt (1) of a conveyor belt system for transported material (6), wherein, in order to strip transported material (6) adhering to the conveyor belt (1), a stripping segment (9) of the stripping device (8) is advanced onto the conveyor belt (1) with its stripping edge (10) by an advancing drive (13) and at least the advancing force with which the advancing drive (13) advances the at least one stripping segment (9) onto the conveyor belt (1) is regulated as a regulating variable by an electronic controller (14) on the basis of the value, determined by at least one sensor (15), of at least one guide variable.

Abstract: The invention relates to mass spectrometers with optically pumped lasers, whose laser light can be used for ionization by laser desorption, for the fragmentation of ions by photodissociation (PD), for the initiation of ion reactions, and for other purposes. The invention provides a laser system for a mass spectrometer, with which at least two laser beams of different wavelengths can be generated for use at different points along an ion path from an ion source to an ion detector in the mass spectrometer.

Abstract: A mixer device for introducing and distributing a liquid into a gas flow comprises a mixing chamber which can be flowed through by the gas flow, an overflow pipe which is arranged at least partly in the mixing chamber and which has a jacket surface and a first and a second pipe end, and at least one injector associated with the first pipe end of the overflow pipe to inject the liquid into the overflow pipe. The jacket surface of the overflow pipe has at least one inflow opening through which gas can flow from the mixing chamber into the overflow pipe for a subsequent mixing with the injected fluid. The overflow pipe is configured such that inflowing gas in its interior can have two swirl components of opposite senses imparted onto it.