Abstract: Arrangements are described for evaluating characteristics of target molecules. A biochip is received which includes a substrate to which charged probe molecules are attached. The probe molecules have a marker to allow generating signals indicative of the distance of a portion of the probe molecule from the substrate. The signals are detected and means for an external electric field is generated to which the probe molecules are exposed. A control means acts to: (A) apply an external electric field causing the portion of the probe molecule to approach the substrate, and (B) apply an external electric field causing the portion of the probe molecule to move away from the substrate. The signal is recorded as a function of time during step (A) and/or step (B). Steps (A) and (B) are repeated for a predetermined number of times and the recorded signals are combined.

Abstract: Arrangements are described for evaluating characteristics of target molecules. A biochip is received which includes a substrate to which charged probe molecules are attached. The probe molecules have a marker to allow generating signals indicative of the distance of a portion of the probe molecule from the substrate. The signals are detected and means for an external electric field is generated to which the probe molecules are exposed. A control means acts to: (A) apply an external electric field causing the portion of the probe molecule to approach the substrate, and (B) apply an external electric field causing the portion of the probe molecule to move away from the substrate. The signal is recorded as a function of time during step (A) and/or step (B). Steps (A) and (B) are repeated for a predetermined number of times and the recorded signals are combined.

Abstract: Arrangements are described for evaluating characteristics of target molecules. A biochip is received which includes a substrate to which charged probe molecules are attached. The probe molecules have a marker to allow generating signals indicative of the distance of a portion of the probe molecule from the substrate. The signals are detected and means for an external electric field is generated to which the probe molecules are exposed. A control means acts to: (A) apply an external electric field causing the portion of the probe molecule to approach the substrate, and (B) apply an external electric field causing the portion of the probe molecule to move away from the substrate. The signal is recorded as a function of time during step (A) and/or step (B). Steps (A) and (B) are repeated for a predetermined number of times and the recorded signals are combined.

Abstract: The invention relates to a valve arrangement with a pressure limiting valve and a flow regulator valve, which comprises a flow regulator piston, having at least one first hydraulic resistor, distinguished in that the flow regulator valve's (5) flow regulator piston (15) has a split pressure return surface and in that the first part (ring surface (45)) of the pressure return surface is capable of working at a pressure p1 and a second part (annulus surface (31)) of the pressure return surface is capable of working at a pressure p2.

Abstract: The invention relates to a valve arrangement with a pressure limiting valve and a flow regulator valve, which comprises a flow regulator piston, having at least one first hydraulic resistor, distinguished in that the flow regulator valve's (5) flow regulator piston (15) has a split pressure return surface and in that the first part (ring surface (45)) of the pressure return surface is capable of working at a pressure p1 and a second part (annulus surface (31)) of the pressure return surface is capable of working at a pressure p2.

Abstract: The invention relates to a valve arrangement with a pressure limiting valve and a flow regulator valve, which comprises a flow regulator piston, having at least one first hydraulic resistor, distinguished in that the flow regulator valve's (5) flow regulator piston (15) has a split pressure return surface and in that the first part (ring surface (45)) of the pressure return surface is capable of working at a pressure p1 and a second part (annulus surface (31)) of the pressure return surface is capable of working at a pressure p2.